1. Articles from Dong Myung Kim

    1-24 of 28 1 2 »
    1. Assessment of Optical Coherence Tomography Color Probability Codes in Myopic Glaucoma Eyes After Applying a Myopic Normative Database

      Assessment of Optical Coherence Tomography Color Probability Codes in Myopic Glaucoma Eyes After Applying a Myopic Normative Database

      We thank Drs Qiu and Zhang for their interest in our article. 1 Their comments focused on the possible influence of age, axial length, and disc size on the diagnostic performance of peripapillary retinal nerve fiber layer (RNFL) measurements. In this correspondence, we would like to expand our discussion in response to the comments raised by Drs Qiu and Zhang.

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    2. Assessment of OCT color probability codes in myopic glaucoma eyes after applying a myopic normative database

      Assessment of OCT color probability codes in myopic glaucoma eyes after applying a myopic normative database

      Purpose To evaluate the optical coherence tomography (OCT) color probability codes based on a myopic normative database and to investigate whether the implementation of the myopic normative database can improve the OCT diagnostic ability in myopic glaucoma. Design Comparative validity study. Methods In this study, 305 eyes (154 myopic healthy eyes and 151 myopic glaucoma eyes) were included. A myopic normative database was obtained based on myopic healthy eyes. We evaluated the agreement between OCT color probability codes after applying the built-in and myopic normative databases, respectively. Another 120 eyes (60 myopic healthy eyes and 60 myopic glaucoma eyes) were ...

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    3. Glaucoma Diagnostic Ability of Layer-by-Layer Segmented Ganglion Cell Complex by Spectral-Domain Optical Coherence Tomography

      Glaucoma Diagnostic Ability of Layer-by-Layer Segmented Ganglion Cell Complex by Spectral-Domain Optical Coherence Tomography

      Purpose : To evaluate the diagnostic ability of layer-by-layer segmented macular ganglion cell complex (GCC) using spectral-domain optical coherence tomography (OCT) for detection of glaucoma and to analyze the topographic patterns of the segmented thicknesses in open-angle glaucoma. Methods : Seventy-seven open-angle glaucoma patients and 59 healthy subjects were enrolled in this cross-sectional study. Spectral-domain OCT with automated segmentation was used to measure the separate thicknesses of macular retinal nerve fiber layer (mRNFL), ganglion cell layer (GCL), and inner plexiform layer (IPL). We compared the specific diagnostic abilities of the GCC (RNFL+GCL+IPL), ganglion cell–inner plexiform layer (GCIPL: GCL+IPL ...

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    4. Spectral-domain optical coherence tomography in manifest glaucoma: its additive role in structural diagnosis

      Spectral-domain optical coherence tomography in manifest glaucoma: its additive role in structural diagnosis

      Purpose To investigate the additive role of spectral-domain optical coherence tomography (SD-OCT) in the structural diagnosis in glaucoma. Design Reliability and validity analysis. Methods Structural examinations from 109 eyes of 109 healthy individuals and 151 eyes of 151 glaucoma patients with different severities were included. Four structural-diagnostic examination sets were prepared using stereo optic disc photography (SDP), red-free retinal nerve fiber layer photography (RNFLP), and SD-OCT: (1) SDP (S), (2) SDP and SD-OCT (SO), (3) SDP and RNFLP (SR), and (4) SDP, RNFLP, and SD-OCT (SRO). Five glaucoma specialists were instructed to classify subjects as normal or glaucoma using each ...

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    5. Macular Ganglion Cell Imaging Study: Covariate Effects on the Spectral Domain Optical Coherence Tomography for Glaucoma Diagnosis

      Macular Ganglion Cell Imaging Study: Covariate Effects on the Spectral Domain Optical Coherence Tomography for Glaucoma Diagnosis

      Purpose To evaluate the effect of multiple covariates on the diagnostic performance of the Cirrus high-definition optical coherence tomography (HD-OCT) for glaucoma detection. Methods A prospective case-control study was performed and included 173 recently diagnosed glaucoma patients and 63 unaffected individuals from the Macular Ganglion Cell Imaging Study. Regression analysis of receiver operating characteristic were conducted to evaluate the influence of age, spherical equivalent, axial length, optic disc size, and visual field index on the macular ganglion cell-inner plexiform layer (GCIPL) and peripapillary retinal nerve fiber layer (RNFL) measurements. Results Disease severity, as measured by visual field index, had a ...

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    6. Clinical Use of an Optical Coherence Tomography Linear Discriminant Function for Differentiating Glaucoma From Normal Eyes

      Clinical Use of an Optical Coherence Tomography Linear Discriminant Function for Differentiating Glaucoma From Normal Eyes

      Purpose: To determine and validate the diagnostic ability of a linear discriminant function (LDF) based on retinal nerve fiber layer (RNFL) and ganglion cell-inner plexiform layer (GCIPL) thickness obtained using high-definition optical coherence tomography (Cirrus HD-OCT) for discriminating between healthy controls and early glaucoma subjects. Methods: We prospectively selected 214 healthy controls and 152 glaucoma subjects (teaching set) and another independent sample of 86 healthy controls and 71 glaucoma subjects (validating set). Two scans, including 1 macular and 1 peripapillary RNFL scan, were obtained. After calculating the LDF in the teaching set using the binary logistic regression analysis, receiver operating ...

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    7. Additive Diagnostic Role of Imaging in Glaucoma: Optical Coherence Tomography and Retinal Nerve Fiber Layer Photography

      Additive Diagnostic Role of Imaging in Glaucoma: Optical Coherence Tomography and Retinal Nerve Fiber Layer Photography

      Purpose: To investigate the additive diagnostic role of spectral-domain optical coherence tomography (SD-OCT) and red-free retinal nerve fiber layer photography (RNFLP) in making clinical glaucoma diagnosis. Methods: Four diagnostic combination sets, including the most recent image from each measurement of 196 glaucoma eyes (including the 44 preperimetric glaucoma eyes) and 101 healthy eyes, were prepared: (1) stereo disc photography and Humphrey visual field (SH); (2) SH and SD-OCT (SHO); (3) SH and RNFLP (SHR); 4) SHR and SD-OCT (SHRO). Each randomly sorted set was serially presented at one-month intervals to five glaucoma specialists who were asked to evaluate them in ...

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    8. Combination of optic disc rim area and retinal nerve fiber layer thickness for early glaucoma detection by using spectral domain OCT

      Combination of optic disc rim area and retinal nerve fiber layer thickness for early glaucoma detection by using spectral domain OCT

      BACKGROUND: To compare the diagnostic ability of optic disc rim area (RA), retinal nerve fiber layer thickness (RNFLT), and their combination on sector-based analysis of spectral domain optical coherence tomography (Cirrus OCT) in discriminating subjects with early-stage open angle glaucoma (OAG) from normal subjects. METHODS: RA and RNFLT of 78 early OAG and 80 normal subjects were measured on Cirrus OCT at the global area, 4 quadrants, 12 clock hours, and 7 + 11 o'clock (a sector that includes 7 and 11 o'clock). A new parameter, RR (a multiplication of the RA and RNFLT) was derived to identify the ...

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    9. Comparison of ability of time-domain and spectral-domain optical coherence tomography to detect diffuse retinal nerve fiber layer atrophy

      Comparison of ability of time-domain and spectral-domain optical coherence tomography to detect diffuse retinal nerve fiber layer atrophy

      Purpose Our aim was to evaluate and compare diagnostic capabilities of time-domain (Stratus) and spectral-domain (Cirrus) optical coherence tomography (OCT) to detect diffuse retinal nerve fiber layer (RNFL) atrophy. Methods This study assessed 101 eyes from 101 glaucoma patients with diffuse RNFL atrophy and 101 eyes from 101 age-matched healthy individuals. Two experienced glaucoma specialists graded red-free RNFL photographs of eyes with diffuse RNFL atrophy using a four-level grading system. The area under the receiver operating characteristic curves (AUC) of normal eyes was compared with that of eyes with diffuse atrophy. Sensitivity and specificity of each OCT device were calculated ...

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    10. Macular Ganglion Cell Imaging Study: Glaucoma Diagnostic Accuracy of Spectral-Domain Optical Coherence Tomography

      Macular Ganglion Cell Imaging Study: Glaucoma Diagnostic Accuracy of Spectral-Domain Optical Coherence Tomography

      Purpose: To evaluate the diagnostic accuracy of macular ganglion cell-inner plexiform layer (GCIPL) measurements using high-definition optical coherence tomography (Cirrus HD-OCT) ganglion cell analysis algorithm for detecting early and moderate to severe glaucoma. Methods: One hundred and nineteen normal subjects and 306 glaucoma patients (164 patients with early glaucoma and 142 with moderate to severe glaucoma) were enrolled from the Macular Ganglion Cell Imaging Study. Macular GCIPL, peripapillary retinal nerve fiber layer (RNFL) thickness, and optic nerve head (ONH) parameters were measured in each subject. Areas under the receiver operating characteristic curves (AUROCs) were calculated and compared. Based on the ...

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    11. Comparison of two different spectral domain optical coherence tomography devices in the detection of localized retinal nerve fiber layer defects

      Comparison of two different spectral domain optical coherence tomography devices in the detection of localized retinal nerve fiber layer defects

      Purpose To compare the detection of localized retinal nerve fiber layer (RNFL) defects by two different spectral domain optical coherence tomography (SD-OCT) devices. Methods Eyes of 42 normal control subjects and 48 patients with a localized RNFL defect on red-free fundus photographs were imaged by the Cirrus (Carl Zeiss Meditec, Dublin, CA, USA) and 3D OCT (Topcon, Tokyo, Japan) devices. We compared sensitivities, specificities, and area under the receiver operating characteristic curves (AUCs) of circumpapillary RNFL (cpRNFL) thickness and ganglion cell complex (GCC) parameters between the two devices. Results The devices provided different cpRNFL thickness measurements. The highest sensitivities at ...

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    12. Glaucoma Detection Ability of Ganglion Cell-Inner Plexiform Layer Thickness by Spectral-Domain Optical Coherence Tomography in High Myopia

      Glaucoma Detection Ability of Ganglion Cell-Inner Plexiform Layer Thickness by Spectral-Domain Optical Coherence Tomography in High Myopia

      Purpose: To compare the glaucoma detection ability of macular ganglion cell-inner plexiform layer (GCIPL) thickness measured with Cirrus spectral-domain optical coherence tomography (SD-OCT) with that of peripapillary retinal nerve fiber layer (RNFL) thickness in high myopia. Methods: In 49 highly myopic and 54 non-highly myopic glaucoma patients along with 78 healthy myopic subjects, two scans, including one macular scan and one peripapillary RNFL scan, were obtained using Cirrus SD-OCT. For 44 randomly selected glaucoma patients, three macular scans were taken for reproducibility measurements. The glaucoma detection abilities of macular GCIPL and peripapillary RNFL thicknesses were compared between the highly myopic ...

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    13. Diagnostic Ability of Spectral-domain Versus Time-domain Optical Coherence Tomography in Preperimetric Glaucoma

      Diagnostic Ability of Spectral-domain Versus Time-domain Optical Coherence Tomography in Preperimetric Glaucoma

      Purpose: To evaluate and compare the diagnostic abilities of the speckle noise-reduced spectral-domain optical coherence tomography (SD-OCT; Spectralis OCT) and time-domain optical coherence tomography (TD-OCT; Stratus OCT) to detect localized retinal nerve fiber layer (RNFL) defects in patients with preperimetric open-angle glaucoma. Methods: Thirty-five eyes of 35 preperimetric glaucoma patients with localized RNFL defects and 72 normal control eyes were scanned using SD-OCT and TD-OCT. Areas under the receiver-operating characteristic curves (AUROCs), and the sensitivity and specificity for detecting localized RNFL defects based on the internal normative database of each device were calculated and compared. Results: The AUROC for the ...

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    14. Long-Term Reproducibility of Cirrus HD Optical Coherence Tomography Deviation Map in Clinically Stable Glaucomatous Eyes

      Long-Term Reproducibility of Cirrus HD Optical Coherence Tomography Deviation Map in Clinically Stable Glaucomatous Eyes

      Objective To determine the long-term reproducibility of the retinal nerve fiber layer (RNFL) thickness deviation map in glaucoma patients. Design Retrospective, longitudinal study. Participants One hundred two eyes of 102 glaucoma patients. Methods From a total of 318 screened glaucoma patients who had undergone at least 3 serial Cirrus HD optical coherence tomography sessions during an 18-month or longer follow-up period, 102 eyes with localized RNFL defects on red-free photographs that did not progress during this period based on stereoscopic disc photography, red-free photography, and standard automated perimetry (SAP) were included. The angular widths from the RNFL thickness deviation maps ...

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    15. Detection of Localized Retinal Nerve Fiber Layer Defects with Posterior Pole Asymmetry Analysis of Spectral-domain Optical Coherence Tomography

      Detection of Localized Retinal Nerve Fiber Layer Defects with Posterior Pole Asymmetry Analysis of Spectral-domain Optical Coherence Tomography

      Purpose:To investigate the diagnostic ability of posterior pole asymmetry analysis (PPAA) with spectral domain optical coherence tomography (Spectralis SD-OCT, Heidelberg Engineering, Heidelberg, Germany) for detecting localized retinal nerve fiber layer (RNFL) defects. Methods:Eighty-four open-angle glaucoma subjects (84 eyes) with localized, wedge-shape RNFL defects by red-free RNFL photography and 122 eyes of normal subjects were enrolled. The subjects were examined by SD-OCT to obtain circumpapillary RNFL (cpRNFL) thickness as well as PPAA. The PPAA provides a corresponding cell to cell comparison between hemispheres within the central 20° and presents the difference using gray scale. Area under the receiver operating ...

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    16. Three-Dimensional Evaluation of the Lamina Cribrosa Using Spectral-Domain Optical Coherence Tomography in Glaucoma

      Three-Dimensional Evaluation of the Lamina Cribrosa Using Spectral-Domain Optical Coherence Tomography in Glaucoma

      Purpose. To introduce a novel, digital, three-dimensional (3D) reconstruction of the optic nerve head (ONH) and to use this method to evaluate the 3D configuration of the lamina cribrosa (LC) in patients with primary open-angle glaucoma. Methods. Optic discs of 137 eyes of 137 patients with open-angle glaucoma were scanned with enhanced depth-imaging spectral domain-optical coherence tomography (SD-OCT). 3D images of the ONH were then reconstructed from B-scan images using maximum intensity projection (MIP) and texture-based volume rendering (VRT). The performance of the threshold segmentation by MIP and VRT was assessed by comparing the distance of the anterior LC surface ...

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    17. 3-Dimensional Evaluation of the Lamina Cribrosa Using Spectral Domain Optical Coherence Tomography in Glaucoma

      3-Dimensional Evaluation of the Lamina Cribrosa Using Spectral Domain Optical Coherence Tomography in Glaucoma
      Purpose: To introduce a novel, digital 3-dimensional (3D) reconstruction of the optic nerve head (ONH) and to evaluate the 3D configuration of the lamina cribrosa (LC) in patients with primary open angle glaucoma using this method. Methods: Optic discs of 137 eyes of 137 patients with open angle glaucoma were scanned with enhanced depth imaging spectral domain-optical coherence tomography (SD-OCT). 3D images of the ONH then were reconstructed from B scan images using maximum intensity projection (MIP) and texture based-volume rendering (VRT). The performance of the threshold segmentation by MIP and VRT was assessed by comparing the distance of the ...
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    18. Diagnostic Accuracy of OCT with a Normative Database to Detect Diffuse Retinal Nerve Fiber Layer Atrophy: Diffuse Atrophy Imaging Study

      Diagnostic Accuracy of OCT with a Normative Database to Detect Diffuse Retinal Nerve Fiber Layer Atrophy: Diffuse Atrophy Imaging Study

      Purpose: To investigate the diagnostic accuracy of Stratus optical coherence tomography (OCT) with its internal normative database to detect diffuse retinal nerve fiber layer (RNFL) atrophy in glaucoma subjects. Methods: One hundred two eyes of 102 glaucoma patients with diffuse RNFL atrophy and 102 healthy eyes of 102 age-matched subjects were enrolled in the Diffuse Atrophy Imaging Study. Two experienced observers graded RNFL photographs of diffuse RNFL atrophy eyes using a four-level grading system. The diagnostic performances for detecting diffuse RNFL atrophy were examined according to the visual field results as well as the RNFL photographs grading. Results: Using a ...

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    19. Glaucoma Progression After the First-detected Optic Disc Hemorrhage by Optical Coherence Tomography

      Glaucoma Progression After the First-detected Optic Disc Hemorrhage by Optical Coherence Tomography

      Purpose: To evaluate the progression of glaucoma after first detected disc hemorrhage (DH) by time-domain optical coherence tomography (OCT). Methods: Forty-four eyes with a unilateral DH were allocated to the DH group and 44 fellow eyes to the non-DH group. OCT signal decrease indicating retinal nerve fiber layer thinning was defined as a decrease beyond the upper 95% limit of test-retest variability defined at the 95% confidence level of 44 control patients. The DH and non-DH groups were compared in terms of OCT-derived glaucoma progressions after the first detected DH. In addition, clock-hour locations of the OCT-derived progression were compared ...

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    20. Visualization of the Lamina Cribrosa Using Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography

      Visualization of the Lamina Cribrosa Using Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography

      Purpose To investigate whether the enhanced depth imaging technique (EDI) may improve the visualization of the lamina cribrosa using spectral-domain optical coherence tomography (SD-OCT). Design Prospective observational case series. Methods Images of the optic nerve were obtained in 10 normal subjects, 7 glaucoma suspects, and 18 glaucoma patients by positioning an SD-OCT in the usual fashion, as well as close enough to the eye to obtain an inverted representation of the fundus (EDI). In addition to these single line scans, approximately 65 sections were obtained within a 10 × 15-degree rectangle covering the optic nerve head using EDI. The “depth of ...

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    21. Changes in Anterior Chamber Configuration after Cataract Surgery as Measured by Anterior Segment Optical Coherence Tomography

      Changes in Anterior Chamber Configuration after Cataract Surgery as Measured by Anterior Segment Optical Coherence Tomography

      Purpose To evaluate the changes in anterior chamber depth (ACD) and angle width induced by phacoemulsification and intraocular lens (IOL) implantation in normal eyes using anterior segment optical coherence tomography (AS-OCT). Methods Forty-five eyes (45 patients) underwent AS-OCT imaging to evaluate anterior chamber configuration before and 2 days after phacoemulsification and IOL implantation. We analyzed the central ACD and angle width using different methods: anterior chamber angle (ACA), trabecular-iris angle (TIA), angle opening distance (AOD), and trabecular iris surface area (TISA) in the nasal and temporal quadrants. Comparison between preoperative and postoperative measurement was done using paired t-tests and each ...

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    22. Trend-based Analysis of Retinal Nerve Fiber Layer Thickness Measured by Optical Coherence Tomography in Eyes with Localized Nerve Fiber Layer Defects

      Trend-based Analysis of Retinal Nerve Fiber Layer Thickness Measured by Optical Coherence Tomography in Eyes with Localized Nerve Fiber Layer Defects
      Purpose. To evaluate the rate of change in retinal nerve fiber layer (RNFL) thickness measured by optical coherence tomography (OCT) in eyes with stable and progressive localized RNFL defects, and to investigate the diagnostic capability of OCT in the detection of progressive RNFL thinning using a trend-based approach. Methods. The study included 153 glaucomatous eyes with localized RNFL defects. Patients were divided into nonprogressors (n=77) and progressors (n=76), based on evaluation of serial red-free photographs. The rates of progressive thinning in global, quadrant, and clock-hour OCT RNFL thicknesses were determined using linear regression and compared between groups. Areas ...
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    23. Quantitative Assessment of Diffuse Retinal Nerve Fiber Layer Atrophy Using Optical Coherence Tomography: Diffuse Atrophy Imaging Study

      Quantitative Assessment of Diffuse Retinal Nerve Fiber Layer Atrophy Using Optical Coherence Tomography: Diffuse Atrophy Imaging Study

      Purpose To evaluate quantitatively the degree of diffuse retinal nerve fiber layer (RNFL) atrophy using Stratus optical coherence tomography (OCT). Design Prospective, cross-sectional study. Participants One hundred two eyes of 102 patients with diffuse RNFL atrophy and 102 healthy eyes of 102 age-matched subjects were enrolled in the Diffuse Atrophy Imaging Study. Methods Two experienced observers graded RNFL photographs of diffuse RNFL atrophy eyes using a previously reported standardized protocol with a 4-level grading system. Readings were taken from the superior and inferior RNFL areas. The OCT-measured RNFL thickness parameters were compared among normal eyes and diffuse atrophy subgroups. Area ...

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    24. Quantitative Assessment of Diffuse Retinal Nerve Fiber Layer Atrophy Using Optical Coherence Tomography: Diffuse Atrophy Imaging Study

      Quantitative Assessment of Diffuse Retinal Nerve Fiber Layer Atrophy Using Optical Coherence Tomography: Diffuse Atrophy Imaging Study

      Purpose: To evaluate quantitatively the degree of diffuse retinal nerve fiber layer (RNFL) atrophy using Stratus optical coherence tomography (OCT).Design: Prospective, cross-sectional study.Participants: One hundred two eyes of 102 patients with diffuse RNFL atrophy and 102 healthy eyes of 102 age-matched subjects were enrolled in the Diffuse Atrophy Imaging Study.Methods: Two experienced observers graded RNFL photographs of diffuse RNFL atrophy eyes using a previously reported standardized protocol with a 4-level grading system. Readings were taken from the superior and inferior RNFL areas. The OCT-measured RNFL thickness parameters were compared among normal eyes and diffuse atrophy subgroups. Area ...

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    1-24 of 28 1 2 »
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    1. (27 articles) Seoul National University
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    Korean normative database for time domain optical coherence tomography to detect localized retinal nerve fiber layer defects (preliminary study) Quantitative Assessment of Diffuse Retinal Nerve Fiber Layer Atrophy Using Optical Coherence Tomography: Diffuse Atrophy Imaging Study Changes in Anterior Chamber Configuration after Cataract Surgery as Measured by Anterior Segment Optical Coherence Tomography Visualization of the Lamina Cribrosa Using Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography Diagnostic Accuracy of OCT with a Normative Database to Detect Diffuse Retinal Nerve Fiber Layer Atrophy: Diffuse Atrophy Imaging Study Glaucoma Progression After the First-detected Optic Disc Hemorrhage by Optical Coherence Tomography Detection of Localized Retinal Nerve Fiber Layer Defects with Posterior Pole Asymmetry Analysis of Spectral-domain Optical Coherence Tomography A Generic Framework for Fourier-Domain Optical Coherence Tomography Imaging: Software Architecture and Hardware Implementations Vision-Inspection-Synchronized Dual Optical Coherence Tomography for High-Resolution Real-Time Multidimensional Defect Tracking in Optical Thin Film Industry Relative retinal flow velocity detection using optical coherence tomography angiography imaging Comparison of Optical Flow Ratio and Fractional Flow Ratio in Stent-Treated Arteries Immediately After Percutaneous Coronary Intervention Spaceflight Associated Neuro-Ocular Syndrome (SANS): A Systematic Review and Future Directions