1. Articles from Ke Xu

    1-3 of 3
    1. Measurement of a multi-layered tear film phantom using optical coherence tomography and statistical decision theory

      Measurement of a multi-layered tear film phantom using optical coherence tomography and statistical decision theory

      To extend our understanding of tear film dynamics for the management of dry eye disease, we propose a method to optically sense the tear film and estimate simultaneously the thicknesses of the lipid and aqueous layers. The proposed method, SDT-OCT, combines ultra-high axial resolution optical coherence tomography (OCT) and a robust estimator based on statistical decision theory (SDT) to achieve thickness measurements at the nanometer scale. Unlike conventional Fourier-domain OCT where peak detection of layers occurs in Fourier space, in SDT-OCT thickness is estimated using statistical decision theory directly on the raw spectra acquired with the OCT system. In this ...

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    2. Optical Coherence Tomographic Evaluation of Transplant Coronary Artery Vasculopathy With Correlation to Cellular Rejection

      Optical Coherence Tomographic Evaluation of Transplant Coronary Artery Vasculopathy With Correlation to Cellular Rejection

      Background— Cardiac allograft vasculopathy is an accelerated fibroproliferative process that affects the coronary arteries of transplant ed hearts. Intra coronary imaging with optical coherence to mography enables detection of subangiographic cardiac allograft vasculopathy . Methods and Results— At the time of routine surveillance coronary angiography, 48 consecutive heart transplant recipients underwent optical coherence tomographic imaging of 1 coronary artery . Imaging findings were compared per rejection his to ry that was graded according to the International Society of Heart and Lung Transplant ation classification as none/mild (International Society of Heart and Lung Transplant ation 0, 1A/1B, or 2) or high-grade ...

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    3. Nondestructive metrology of layered polymeric optical materials using optical coherence tomography

      Nondestructive metrology of layered polymeric optical materials using optical coherence tomography

      In recent years, there has been an ever-growing interest in exploring novel, highly efficient optical materials to develop compact and effective optical components. The design and fabrication of high-performance optics require nondestructive metrology techniques to inspect the samples. We have investigated the capability of optical coherence tomography (OCT) to nondestructively characterize layered polymeric materials. Using a swept-source OCT system with a wavelength range of 1.25 - 1.41 μm, we achieved micron-scale three-dimensional visualization of the interior structures and details of the layered polymers. The 3D OCT imaging also enabled accurate identification of the locations of defects within the samples ...

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    1-3 of 3
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  2. Topics in the News

    1. (3 articles) Ke Xu
    2. (2 articles) Zhejiang University
    3. (2 articles) Jannick P. Rolland
    4. (1 articles) Cardiovascular Research Foundation
    5. (1 articles) Columbia University
    6. (1 articles) University of Arizona
    7. (1 articles) University of Rochester
    8. (1 articles) Gary S. Mintz
    9. (1 articles) Panomsak Meemon
    10. (1 articles) Kye-Sung Lee
    11. (1 articles) Pei Ma
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    Nondestructive metrology of layered polymeric optical materials using optical coherence tomography Optical Coherence Tomographic Evaluation of Transplant Coronary Artery Vasculopathy With Correlation to Cellular Rejection Measurement of a multi-layered tear film phantom using optical coherence tomography and statistical decision theory Three-dimensional detection and quantification of defects in SiC by optical coherence tomography University of Illinois at Chicago Receives NIH Grant for Functional Tomography of Neurovascular Coupling Interactions in Healthy and Diseased Retinas Dyad Medical Receives NIH Grant for Software For OCT Analysis of Vascular Stents Oregon Health and Science University Receives NIH Grant for Application of Ultrahigh-Speed Long-Range Wide-Field OCT in Anterior Eye Diseases Optical coherence tomography and fractional flow reserve guided treatment of woven coronary artery anomaly presenting as acute myocardial infarction Impact of manual correction over automated segmentation of spectral domain optical coherence tomography The 360° circumferential opening of Schlemm's canal in normal individuals detected by enhanced depth imaging optical coherence tomography Real-Time Intraoperative Dynamics of White Cataract- Intraoperative Optical Coherence Tomography Guided Classification & Management Quantitative Optical Coherence Tomography Angiography Biomarkers in a Treat-and-Extend Dosing Regimen in Neovascular Age-Related Macular Degeneration