1. Articles from Ke Xu

    1-3 of 3
    1. Measurement of a multi-layered tear film phantom using optical coherence tomography and statistical decision theory

      Measurement of a multi-layered tear film phantom using optical coherence tomography and statistical decision theory

      To extend our understanding of tear film dynamics for the management of dry eye disease, we propose a method to optically sense the tear film and estimate simultaneously the thicknesses of the lipid and aqueous layers. The proposed method, SDT-OCT, combines ultra-high axial resolution optical coherence tomography (OCT) and a robust estimator based on statistical decision theory (SDT) to achieve thickness measurements at the nanometer scale. Unlike conventional Fourier-domain OCT where peak detection of layers occurs in Fourier space, in SDT-OCT thickness is estimated using statistical decision theory directly on the raw spectra acquired with the OCT system. In this ...

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    2. Optical Coherence Tomographic Evaluation of Transplant Coronary Artery Vasculopathy With Correlation to Cellular Rejection

      Optical Coherence Tomographic Evaluation of Transplant Coronary Artery Vasculopathy With Correlation to Cellular Rejection

      Background— Cardiac allograft vasculopathy is an accelerated fibroproliferative process that affects the coronary arteries of transplant ed hearts. Intra coronary imaging with optical coherence to mography enables detection of subangiographic cardiac allograft vasculopathy . Methods and Results— At the time of routine surveillance coronary angiography, 48 consecutive heart transplant recipients underwent optical coherence tomographic imaging of 1 coronary artery . Imaging findings were compared per rejection his to ry that was graded according to the International Society of Heart and Lung Transplant ation classification as none/mild (International Society of Heart and Lung Transplant ation 0, 1A/1B, or 2) or high-grade ...

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    3. Nondestructive metrology of layered polymeric optical materials using optical coherence tomography

      Nondestructive metrology of layered polymeric optical materials using optical coherence tomography

      In recent years, there has been an ever-growing interest in exploring novel, highly efficient optical materials to develop compact and effective optical components. The design and fabrication of high-performance optics require nondestructive metrology techniques to inspect the samples. We have investigated the capability of optical coherence tomography (OCT) to nondestructively characterize layered polymeric materials. Using a swept-source OCT system with a wavelength range of 1.25 - 1.41 μm, we achieved micron-scale three-dimensional visualization of the interior structures and details of the layered polymers. The 3D OCT imaging also enabled accurate identification of the locations of defects within the samples ...

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    1-3 of 3
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  2. Topics in the News

    1. (3 articles) Ke Xu
    2. (2 articles) Zhejiang University
    3. (2 articles) Jannick P. Rolland
    4. (2 articles) Massachusetts General Hospital
    5. (2 articles) Harvard University
    6. (2 articles) Guillermo J. Tearney
    7. (1 articles) Cardiovascular Research Foundation
    8. (1 articles) Columbia University
    9. (1 articles) University of Arizona
    10. (1 articles) University of Rochester
    11. (1 articles) Gary S. Mintz
    12. (1 articles) Panomsak Meemon
    13. (1 articles) Kye-Sung Lee
    14. (1 articles) University of São Paulo
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    Nondestructive metrology of layered polymeric optical materials using optical coherence tomography Optical Coherence Tomographic Evaluation of Transplant Coronary Artery Vasculopathy With Correlation to Cellular Rejection Measurement of a multi-layered tear film phantom using optical coherence tomography and statistical decision theory Postdoctoral Research Fellowships (Optical Coherence Tomography) at Massachusetts General Hosptial Postdoctoral Research Fellowships (In Vivo Microscopy) At Massachusetts General Hospital Circumpapillary and macular vessel density assessment by optical coherence tomography angiography in eyes with temporal hemianopia from chiasmal compression. Correlation with retinal neural and visual field loss Miniaturizing medical imaging, sensing technology On-chip tunable photonic delay line Canon Xephilio OCT-A1 Optical Coherence Tomography Device Receives FDA 510(k) Clearance Subintimal Versus Intraplaque Recanalization of Coronary Chronic Total Occlusions: Mid-Term Angiographic and OCT Findings From the ISAR-OCT-CTO Registry Review of methods and applications of attenuation coefficient measurements with optical coherence tomography Techniques in Optical Coherence and Resonance for Sensing (Thesis)