1. Articles from Hicham Tahri

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    1. Optical coherence tomography aspect of crystalline macular dystrophy in Sjögren–Larsson syndrome

      Optical coherence tomography aspect of crystalline macular dystrophy in Sjögren–Larsson syndrome

      Sjögren–Larsson syndrome is an autosomal-recessive disease caused by a deficiency of the microsomal fatty aldehyde dehydrogenase enzyme. The syndrome is defined by congenital ichthyosis, spasticity, mental retardation and ocular features. We report the case of a 10-year-old boy presenting with bilateral visual impairment and photophobia. Fundus examination showed a mark of yellow–white refractile, perifoveal crystals in each eye. Optical coherence tomography (OCT) detected focal reflective structures corresponding to clinically visible intraretinal crystals and macular macrocystoids space. This case is presented to highlight the ocular findings and to evaluate the contribution of OCT in the study of the ...

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    1. (3 articles) National Institutes of Health
    2. (1 articles) Massachusetts Eye and Ear Infirmary
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