1. Articles from Suzan Dziennis

    1-4 of 4
    1. Changes in cochlear blood flow in mice due to loud sound exposure measured with Doppler optical microangiography and laser Doppler flowmetry

      Changes in cochlear blood flow in mice due to loud sound exposure measured with Doppler optical microangiography and laser Doppler flowmetry

      In this work we determined the contributions of loud sound exposure (LSE) on cochlear blood flow (CoBF) in an in vivo anesthetized mouse model. A broadband noise system (20 kHz bandwidth) with an intensity of 119 dB SPL, was used for a period of one hour to produce a loud sound stimulus. Two techniques were used to study the changes in blood flow, a Doppler optical microangiography (DOMAG) system; which can measure the blood flow within individual cochlear vessels, and a laser Doppler flowmetry (LDF) system; which averages the blood flow within a volume (a hemisphere of ~1.5 mm ...

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    2. High quality optical microangiography of ocular microcirculation and measurement of total retinal blood flow in mouse eye

      High quality optical microangiography of ocular microcirculation and measurement of total retinal blood flow in mouse eye

      Visualization and measurement of retinal blood flow (RBF) is important to the diagnosis and management of different eye diseases, including diabetic retinopathy. Optical microangiography (OMAG) is developed for generating 3D dynamic microcirculation image and later refined into ultra-high sensitive OMAG (UHS-OMAG) for true capillary vessels imaging. Here, we present the application of OMAG imaging technique for visualization of depth-resolved vascular network within retina and choroid as well as measurement of total retinal blood flow in mice. A fast speed spectral domain OCT imaging system at 820nm with a line scan rate of 140 kHz was developed to image mouse posterior ...

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    3. Variable-range Doppler optical microangiography using stabilized step scanning and phase variance binarized mask

      Variable-range Doppler optical microangiography using stabilized step scanning and phase variance binarized mask

      Skipping various numbers of A-lines is effective to obtain multi-range velocimetry using Doppler optical coherence tomography (DOCT). High correlation between A-lines is a fundamental prerequisite for DOCT processing. Therefore, high oversampling is normally necessary, especially when skipping A-lines. That requires quite a long time of imaging, which might not be acceptable on some occasions. Step-scanning protocol, which captures repeated A-scans, has been employed for multi-range DOCT previously. We develop it by waiting for the scanner to stabilize, but not capturing continuously. In this way the cross-correlation of step scanning maintains almost constant for all the captured A-lines, and is higher ...

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    4. Quantifying Optical Microangiography Images Obtained from a Spectral Domain Optical Coherence Tomography System

      Quantifying Optical Microangiography Images Obtained from a Spectral Domain Optical Coherence Tomography System

      The blood vessel morphology is known to correlate with several diseases, such as cancer, and is important for describing several tissue physiological processes, like angiogenesis. Therefore, a quantitative method for characterizing the angiography obtained from medical images would have several clinical applications. Optical microangiography (OMAG) is a method for obtaining three-dimensional images of blood vessels within a volume of tissue. In this study we propose to quantify OMAG images obtained with a spectral domain optical coherence tomography system. A technique for determining three measureable parameters (the fractal dimension, the vessel length fraction, and the vessel area density) is proposed and ...

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    1-4 of 4
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  2. Topics in the News

    1. (4 articles) University of Washington
    2. (4 articles) Ruikang K. Wang
    3. (4 articles) Suzan Dziennis
    4. (3 articles) Zhongwei Zhi
    5. (2 articles) Roberto Reif
    6. (2 articles) Massachusetts General Hospital
    7. (1 articles) Oregon Health & Science University
    8. (1 articles) Lin An
    9. (1 articles) Arthur Ho
    10. (1 articles) Alfred L. Nuttall
    11. (1 articles) Xin Yin
    12. (1 articles) Harvard University
    13. (1 articles) The Chinese University of Hong Kong
    14. (1 articles) University of Miami
    15. (1 articles) VU University Amsterdam
    16. (1 articles) David A. Boas
    17. (1 articles) Brett E. Bouma
    18. (1 articles) Johannes F. de Boer
    19. (1 articles) Frank D. Verbraak
    20. (1 articles) Apollo Medical Optics
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    Quantifying Optical Microangiography Images Obtained from a Spectral Domain Optical Coherence Tomography System Variable-range Doppler optical microangiography using stabilized step scanning and phase variance binarized mask High quality optical microangiography of ocular microcirculation and measurement of total retinal blood flow in mouse eye Changes in cochlear blood flow in mice due to loud sound exposure measured with Doppler optical microangiography and laser Doppler flowmetry Optical Coherence Tomography: Critical Tool to Manage Expectations after Cataract Extraction Improving the characterization of ex vivo human brain optical properties using high numerical aperture optical coherence tomography by spatially constraining the confocal parameters Choroidal, macular and ganglion cell layer thickness assessment in Caucasian children measured with spectral domain optical coherence tomography Examination of retinal vascular density changes via optical coherence tomography angiography in patients with glaucoma 3D reconstruction of coronary artery bifurcations from coronary angiography and optical coherence tomography: feasibility, validation, and reproducibility Age- and refraction-related changes in anterior segment anatomical structures measured by swept-source anterior segment OCT The evaluation of juvenile ocular hypertension by optical coherence tomography angiography Superficial capillary perfusion on optical coherence tomography angiography differentiates moderate and severe nonproliferative diabetic retinopathy