1. Articles from Xiao Yang

    1-5 of 5
    1. The developmental changes of retinal microvasculature in children: a quantitative analysis using OCT angiography

      The developmental changes of retinal microvasculature in children: a quantitative analysis using OCT angiography

      Purpose To quantify the macular microvasculature in healthy children of various ages using optical coherence tomography angiography (OCTA) Design Prospective cross-sectional study. Methods 333 normal children aged from 4 to 16 years old were included. OCTA was performed on a 3 X 3 mm area centered on the macular region. Vascular density, perfusion density, fovea avascular zone (FAZ) area, FAZ perimeter and FAZ acircularity index (AI) were measured and adjusted for axial length. The differences were compared among various ages. Results Among the different age groups, macular vascular density and perfusion density both increased with age. (P<0.0001 and ...

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    2. Detecting human articular cartilage degeneration in its early stage with polarization-sensitive optical coherence tomography

      Detecting human articular cartilage degeneration in its early stage with polarization-sensitive optical coherence tomography

      Detecting articular cartilage (AC) degeneration in its early stage plays a critical role in the diagnosis and treatment of osteoarthritis (OA). Polarization-sensitive optical coherence tomography (PS-OCT) is sensitive to the alteration and disruption of collagen organization that happens during OA progression. This study proposes an effective OA evaluating method based on PS-OCT imaging. A slope-based analysis is applied on the phase retardation images to segment articular cartilage into three zones along the depth direction. The boundaries and birefringence coefficients (BRCs) of each zone are quantified. Two parameters, namely phase homogeneity index (PHI) and zonal distinguishability ( D z), are further developed ...

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    3. Features of the Choroidal Structures in Myopic Children Based on Image Binarization of Optical Coherence Tomography

      Features of the Choroidal Structures in Myopic Children Based on Image Binarization of Optical Coherence Tomography

      Purpose : To evaluate the features of the choroidal structures in the eyes of myopic children obtained by enhanced depth imaging optical coherence tomography (EDI-OCT). Methods : Ninety-six myopic children with low to moderate myopia (spherical equivalent refractive error [SER], –5.75 to –1.00 diopter) were included in this cross-sectional study. Ocular biometrics were measured using an optical low-coherence reflectometry device. Data of the choroidal structures extracted from a 7500-µm cross-sectional arc of the choroid extending from the temporal optic disc margin, including the total choroidal area, luminal area, stromal area, and choroidal vascularity index, were determined by image binarization ...

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    4. Impact of Ticagrelor and Aspirin versus Clopidogrel and Aspirin in Symptomatic Patients with Peripheral Arterial Disease: Thrombus Burden Assessed by Optical Coherence Tomography

      Impact of Ticagrelor and Aspirin versus Clopidogrel and Aspirin in Symptomatic Patients with Peripheral Arterial Disease: Thrombus Burden Assessed by Optical Coherence Tomography

      Purpose To compare OCT identified white thrombus decline, neointimal hyperplasia and clinical outcomes of patients treated with ticagrelor plus aspirin with those patients treated with clopidogrel plus aspirin after peripheral interventions. Background Ticagrelor is a potent platelet inhibitor. In patients with coronary artery disease, ticagrelor and aspirin demonstrated reduced rates of stent thrombosis, compared to aspirin and clopidogrel. The clinical importance of potent antiplatelet inhibition after peripheral endovascular interventions is unknown. Methods We enrolled 18 patients with superficial femoral artery disease and the presence of OCT-detected clot post-stent placement. Patients were randomized to 75 mg clopidogrel once daily for 1 ...

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    5. Characteristics of the macula in amblyopic eyes by optical coherence tomography

      Characteristics of the macula in amblyopic eyes by optical coherence tomography

      AIM: To test the hypothesis that amblyopic neuroretina may have an altered thickness when compared to the normal. METHODS: Twenty-five amblyopic, young patients between the ages of 7 and 11 years old were studied. The interested neuroretina areas are defined into 10 sub-regions according to superior-inferior, nasal-temoral, and peri-para axis, which cross the fovela structure. The thicknesses of ten, defined macular regions were separately measured by optical coherence tomography (OCT) and analyzed by t-test. RESULTS: The average thickness of neuroretina in the exact foveola of the amblyopic eyes is larger than that of normal eyes (P<0.05), but the ...

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    1-5 of 5
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    1. (2 articles) Sun Yat-Sen University
    2. (1 articles) University of Texas at Austin
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    Characteristics of the macula in amblyopic eyes by optical coherence tomography Impact of Ticagrelor and Aspirin versus Clopidogrel and Aspirin in Symptomatic Patients with Peripheral Arterial Disease: Thrombus Burden Assessed by Optical Coherence Tomography Features of the Choroidal Structures in Myopic Children Based on Image Binarization of Optical Coherence Tomography Detecting human articular cartilage degeneration in its early stage with polarization-sensitive optical coherence tomography The developmental changes of retinal microvasculature in children: a quantitative analysis using OCT angiography A case report of a coronary myocardial bridge with impaired full-cycle ratio during dobutamine challenge Diagnosis of chronic stage of hypertensive retinopathy based on spectral domain optical coherence tomography A Cross-sectional Optical Coherence Tomography Study in Patients on Taxane-based Therapy and A Case Report with the Literature Review Determination of peripapillary vessel density in optic disc drusen using EDI-OCT and OCT angiography Optical coherence tomography features of neovascularization in proliferative diabetic retinopathy: a systematic review Retinal microvascular metrics in untreated essential hypertensives using optical coherence tomography angiography Optical coherence tomography angiography findings of fellow eye of proliferative macular telangiectasia type 2: Long term study