1. Articles from Kevin P. Thompson

    1-10 of 10
    1. Volumetric rendering and metrology of spherical gradient refractive index lens imaged by angular scan optical coherence tomography system

      Volumetric rendering and metrology of spherical gradient refractive index lens imaged by angular scan optical coherence tomography system

      In this paper, we develop the methodology, including the refraction correction, geometrical thickness correction, coordinate transformation, and layer segmentation algorithms, for 3D rendering and metrology of a layered spherical gradient refractive index (S-GRIN) lens based on the imaging data collected by an angular scan optical coherence tomography (OCT) system. The 3D mapping and rendering enables direct 3D visualization and internal defect inspection of the lens. The metrology provides assessment of the surface geometry, the lens thickness, the radii of curvature of the internal layer interfaces, and the misalignment of the internal S-GRIN distribution with respect to the lens surface. The ...

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    2. MEMS-based handheld scanning probe with pre-shaped input signals for distortion-free images in Gabor-domain optical coherence microscopy

      MEMS-based handheld scanning probe with pre-shaped input signals for distortion-free images in Gabor-domain optical coherence microscopy

      High-speed scanning in optical coherence tomography (OCT) often comes with either compromises in image quality, the requirement for post-processing of the acquired images, or both. We report on distortion-free OCT volumetric imaging with a dual-axis micro-electro-mechanical system (MEMS)-based handheld imaging probe. In the context of an imaging probe with optics located between the 2D MEMS and the sample, we report in this paper on how pre-shaped open-loop input signals with tailored non-linear parts were implemented in a custom control board and, unlike the sinusoidal signals typically used for MEMS, achieved real-time distortion-free imaging without post-processing. The MEMS mirror was ...

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    3. Optical Coherence Tomography Enabling Non Destructive Metrology of Layered Polymeric GRIN Material

      Optical Coherence Tomography Enabling Non Destructive Metrology of Layered Polymeric GRIN Material

      Gradient Refractive INdex (GRIN) optical components have historically fallen short of theoretical expectations. A recent breakthrough is the manufacturing of nanolayered spherical GRIN (S-GRIN) polymer optical elements, where the construction method yields refractive index gradients that exceed 0.08. Here we report on the application of optical coherence tomography (OCT), including micron-class axial and lateral resolution advances, as effective, innovative methods for performing nondestructive diagnostic metrology on S-GRIN. We show that OCT can be used to visualize and quantify characteristics of the material throughout the manufacturing process. Specifically, internal film structure may be revealed and data are processed to extract ...

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    4. Broadband astigmatism-corrected 
Czerny–Turner spectrometer

      Broadband astigmatism-corrected 
Czerny–Turner spectrometer
      e report an optical design for a low-cost optics, broadband, astigmatism-corrected practical spectrometer. An off-the-shelf cylindrical lens is used to remove astigmatism over the full bandwidth. Results show that better than 0.1 nm spectral resolution and more than 50% throughput were achieved over a bandwidth of 400 nm centered at 800 nm.
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    5. Liquid lens enabled optical coherence microscope with Gabor fusion

      Liquid lens enabled optical coherence microscope with Gabor fusion
      A custom optical microscope with an integrated liquid lens to enable an extended depth imaging in biological tissue has been fabricated and shown to provide subcellular resolution using Gabor image fusion in an optical coherence tomography setup. In this paper, we report on the development and assessment path of this technology over the last few years. Specifically, we report on the optical design as well as the MTF prediction and experimental measurements of the new optical microscope head. The microscope head was integrated in a custom optical coherence microscopy setup that is presented. Images of an African frog tadpole, ex ...
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    6. Assessment of a liquid lens enabled in vivo optical coherence microscope

      Assessment of a liquid lens enabled in vivo optical coherence microscope
      The optical aberrations induced by imaging through skin can be predicted using formulas for Seidel aberrations of a plane-parallel plate. Knowledge of these aberrations helps to guide the choice of numerical aperture (NA) of the optics we can use in an implementation of Gabor domain optical coherence microscopy (GD-OCM), where the focus is the only aberration adjustment made through depth. On this basis, a custom-designed, liquid-lens enabled dynamic focusing optical coherence microscope operating at 0.2 NA is analyzed and validated experimentally. As part of the analysis, we show that the full width at half-maximum metric, as a characteristic descriptor ...
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    7. Gabor-based fusion technique for Optical Coherence Microscopy

      Gabor-based fusion technique for Optical Coherence Microscopy
      We recently reported on an Optical Coherence Microscopy technique, whose innovation intrinsically builds on a recently reported - 2 μm invariant lateral resolution by design throughout a 2 mm cubic full-field of view - liquid-lens-based dynamic focusing optical probe [Murali et al.,Optics Letters 34, 145-147, 2009]. We shall report in this paper on the image acquisition enabled by this optical probe when combined with an automatic data fusion method developed and described here to produce an in-focus high resolution image throughout the imaging depth of the sample. An African frog tadpole (Xenopus laevis) was imaged with the novel probe and the ...
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    8. Gabor domain optical coherence microscopy

      Gabor domain optical coherence microscopy
      In this paper, we present a developing technology targeted at clinical imaging, Gabor Domain Optical Coherence Microscopy (GD-OCM), which combines the high resolution imaging of optical coherence microscopy (OCM), high imaging speed of Fourier domain optical coherence tomography (FD-OCT), and invariant lateral resolution of our custom designed dynamic focusing objective. A high lateral resolution optical design of a dynamic-focusing optical probe with no moving parts, which provides an invariant resolution of currently < 3 µm across a 2mm full-field of view and 2mm imaging depth, is presented. Furthermore, an acquisition scheme (using the probe) that is capable of performing automatic real ...
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    9. Three-dimensional adaptive microscopy using embedded liquid lens

      Three-dimensional adaptive microscopy using embedded liquid lens
      We report on the compact optical design of a high-resolution 3D scanning microscope with adaptive optics capability for refocusing with no moving parts designed for clinical research. The optical aberrations arising from refocusing are compensated for as part of the multiconfiguration optical ... [Opt. Lett. 34, 145-147 (2009)]
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    10. Gabor domain optical coherence microscopy

      Gabor domain optical coherence microscopy
      Optical Coherence Microscopy (OCM) is an emerging technology capable of depth sectioning of biological tissue at the micrometer scale. In this paper, we propose a developing technology we call Gabor Domain Optical Coherence Microscopy (GD-OCM), whose innovation is two folds: (1) A high lateral resolution optical design of a dynamic-focusing optical probe with no moving parts, which provides an invariant resolution of currently 3 µm across a 2mm full-field of view and 2mm imaging depth by design; (2) An acquisition scheme (using the probe) that is capable of performing automatic data fusion to render an in-focus high resolution image throughout ...
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    1-10 of 10
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  2. Topics in the News

    1. (10 articles) Kevin P. Thompson
    2. (10 articles) Jannick P. Rolland
    3. (8 articles) University of Rochester
    4. (7 articles) Kye-Sung Lee
    5. (7 articles) Optical Research Associates
    6. (6 articles) University of Central Florida
    7. (6 articles) Supraja Murali
    8. (6 articles) Panomsak Meemon
    9. (1 articles) UCLA
    10. (1 articles) Adrian G. Podoleanu
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    Three-dimensional adaptive microscopy using embedded liquid lens Gabor domain optical coherence microscopy Gabor-based fusion technique for Optical Coherence Microscopy Assessment of a liquid lens enabled in vivo optical coherence microscope Gabor domain optical coherence microscopy Liquid lens enabled optical coherence microscope with Gabor fusion Broadband astigmatism-corrected 
Czerny–Turner spectrometer Optical Coherence Tomography Enabling Non Destructive Metrology of Layered Polymeric GRIN Material MEMS-based handheld scanning probe with pre-shaped input signals for distortion-free images in Gabor-domain optical coherence microscopy Volumetric rendering and metrology of spherical gradient refractive index lens imaged by angular scan optical coherence tomography system Chalcogenide-glass polarization-maintaining photonic crystal fiber for mid-infrared supercontinuum generation Supervised machine learning based multi-task artificial intelligence classification of retinopathies