1. Articles from Sabine Kling

    1-3 of 3
    1. Observation of sound-induced corneal vibrational modes by optical coherence tomography

      Observation of sound-induced corneal vibrational modes by optical coherence tomography

      The mechanical stability of the cornea is critical for maintaining its normal shape and refractive function. Here, we report an observation of the mechanical resonance modes of the cornea excited by sound waves and detected by using phase-sensitive optical coherence tomography. The cornea in bovine eye globes exhibited three resonance modes in a frequency range of 50-400 Hz. The vibration amplitude of the fundamental mode at 80-120 Hz was ~8 µm at a sound pressure level of 100 dB (2 Pa). Vibrography allows the visualization of the radially symmetric profiles of the resonance modes. A dynamic finite-element analysis supports our ...

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    2. Numerical model of optical coherence tomographic vibrography imaging to estimate corneal biomechanical properties

      Numerical model of optical coherence tomographic vibrography imaging to estimate corneal biomechanical properties

      Most techniques measuring corneal biomechanics in vivo are biased by side factors. We demonstrate the ability of optical coherence tomographic (OCT) vibrography to determine corneal material parameters, while reducing current prevalent restrictions of other techniques (such as intraocular pressure (IOP) and thickness dependency). Modal analysis was performed in a finite-element (FE) model to study the oscillation response in isolated thin corneal flaps/eye globes and to analyse the dependency of the frequency response function on: corneal elasticity, viscoelasticity, geometry (thickness and curvature), IOP and density. The model was verified experimentally in flaps from three bovine corneas and in two enucleated ...

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    3. Dynamic OCT measurement of corneal deformation by an air puff in normal and cross-linked corneas

      Dynamic OCT measurement of corneal deformation by an air puff in normal and cross-linked corneas

      A new technique is presented for the non-invasive imaging of the dynamic response of the cornea to an air puff inducing a deformation. A spectral OCT instrument combined with an air tonometer in a non-collinear configuration was used to image the corneal deformation over full corneal cross-sections, as well as to obtain high speed measurements of the temporal evolution of the corneal apex. The entire deformation process can be dynamically visualized. A quantitative analysis allows direct extraction of several deformation parameters, such as amplitude, diameter and volume of the maximum deformation, as well as duration and speed of the increasing ...

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    1-3 of 3
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  2. Topics in the News

    1. (3 articles) Spanish National Research Council
    2. (3 articles) Susana Marcos
    3. (2 articles) Harvard University
    4. (2 articles) Massachusetts General Hospital
    5. (2 articles) B. Imran Akca
    6. (2 articles) Seok-Hyun Yun
    7. (2 articles) Ernest W. Chang
    8. (1 articles) University of Maryland
    9. (1 articles) Duke University
    10. (1 articles) UCLA
    11. (1 articles) Nippon Medical School
    12. (1 articles) Anthony N. Kuo
    13. (1 articles) Srinivas R. Sadda
    14. (1 articles) Masamichi Takano
    15. (1 articles) Joseph A. Izatt
    16. (1 articles) Oscar Carrasco-Zevallos
    17. (1 articles) Mark Draelos
    18. (1 articles) Heidelberg Spectralis
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    Dynamic OCT measurement of corneal deformation by an air puff in normal and cross-linked corneas Numerical model of optical coherence tomographic vibrography imaging to estimate corneal biomechanical properties Observation of sound-induced corneal vibrational modes by optical coherence tomography Feature of the Week 06/23/2018: Real-time visualization and interaction with static and live optical coherence tomography volumes in immersive virtual reality Automatic Detection and Characterization of Biomarkers in OCT Images Innovative Endoscopies to Be Clinically Used in the Near Future OCT for early quality evaluation of tooth–composite bond in clinical trials A robust model of an OCT signal in a spectral domain Clinical efficacy of aspirin with identification of intimal morphology by optical coherence tomography in preventing event recurrence in patients with vasospasm-induced acute coronary syndrome Retinal Nerve Fiber Layer Thickness Measured by Spectral Domain Optical Coherence Tomography in Healthy Koreans Optical coherence tomography (OCT) angiography of central retinal artery occlusion in the patent cilioretinal artery: a case report Common-path Optical Coherence Tomography using Bessel Beam from Negative Axicon Optical Fiber Tip