1. Articles from Sabine Kling

    1-3 of 3
    1. Observation of sound-induced corneal vibrational modes by optical coherence tomography

      Observation of sound-induced corneal vibrational modes by optical coherence tomography

      The mechanical stability of the cornea is critical for maintaining its normal shape and refractive function. Here, we report an observation of the mechanical resonance modes of the cornea excited by sound waves and detected by using phase-sensitive optical coherence tomography. The cornea in bovine eye globes exhibited three resonance modes in a frequency range of 50-400 Hz. The vibration amplitude of the fundamental mode at 80-120 Hz was ~8 µm at a sound pressure level of 100 dB (2 Pa). Vibrography allows the visualization of the radially symmetric profiles of the resonance modes. A dynamic finite-element analysis supports our ...

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    2. Numerical model of optical coherence tomographic vibrography imaging to estimate corneal biomechanical properties

      Numerical model of optical coherence tomographic vibrography imaging to estimate corneal biomechanical properties

      Most techniques measuring corneal biomechanics in vivo are biased by side factors. We demonstrate the ability of optical coherence tomographic (OCT) vibrography to determine corneal material parameters, while reducing current prevalent restrictions of other techniques (such as intraocular pressure (IOP) and thickness dependency). Modal analysis was performed in a finite-element (FE) model to study the oscillation response in isolated thin corneal flaps/eye globes and to analyse the dependency of the frequency response function on: corneal elasticity, viscoelasticity, geometry (thickness and curvature), IOP and density. The model was verified experimentally in flaps from three bovine corneas and in two enucleated ...

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    3. Dynamic OCT measurement of corneal deformation by an air puff in normal and cross-linked corneas

      Dynamic OCT measurement of corneal deformation by an air puff in normal and cross-linked corneas

      A new technique is presented for the non-invasive imaging of the dynamic response of the cornea to an air puff inducing a deformation. A spectral OCT instrument combined with an air tonometer in a non-collinear configuration was used to image the corneal deformation over full corneal cross-sections, as well as to obtain high speed measurements of the temporal evolution of the corneal apex. The entire deformation process can be dynamically visualized. A quantitative analysis allows direct extraction of several deformation parameters, such as amplitude, diameter and volume of the maximum deformation, as well as duration and speed of the increasing ...

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    1-3 of 3
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  2. Topics in the News

    1. (3 articles) Spanish National Research Council
    2. (3 articles) Susana Marcos
    3. (2 articles) Harvard University
    4. (2 articles) Massachusetts General Hospital
    5. (2 articles) B. Imran Akca
    6. (2 articles) Seok-Hyun Yun
    7. (2 articles) Ernest W. Chang
    8. (1 articles) University of Maryland
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