1. Articles from Ramesh Venkatesh

    1-16 of 16
    1. Utility of multimodal imaging in amelanotic choroidal nevus

      Utility of multimodal imaging in amelanotic choroidal nevus

      An asymptomatic woman presented for a routine eye evaluation with a corrected distance visual acuity of 20/20 in both eyes. Her right ocular examination was within normal limits. Left eye anterior examination was normal and dilated fundus examination showed a well-defined circular flat yellow lesion measuring a 1-disc diameter in size located infero-temporal to the macula possibly at the level of the retinal pigment epithelium (RPE) ( figure 1A ). An enface composite multicolour image showed a dark green coloured region corresponding to the lesion and it appears as a well-defined dark area on the infrared reflectance channel ( figure 1B,C ...

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    2. Spectral domain OCT features in type 2 macular telangiectasia (type 2 MacTel): its relevance with clinical staging and visual acuity

      Spectral domain OCT features in type 2 macular telangiectasia (type 2 MacTel): its relevance with clinical staging and visual acuity

      Background: To report spectral domain optical coherence tomography (SDOCT) imaging findings in type 2 macular telangiectasia (MacTel) and correlate them with clinical stages and visual acuity. Methods: This retrospective, cross-sectional study included type 2 MacTel cases who underwent SDOCT imaging with Spectralis machine. Macular SDOCT images were analysed. Imaging features were tested for correlation with different clinicals stages and visual acuity. Results: 212 eyes of 108 type 2 MacTel patients were included. Hyperreflective middle retinal layer (87%) was the most frequently detected abnormality. This was followed by inner retinal cavities (49%), outward bending of inner retinal layers (35%), retinal pigment ...

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    3. Regression patterns of central serous chorioretinopathy using en face optical coherence tomography

      Regression patterns of central serous chorioretinopathy using en face optical coherence tomography

      Purpose To study the regression patterns of subretinal fluid (SRF) in central serous chorioretinopathy (CSCR) on sequential en face optical coherence tomography (OCT) and its relationship to leak locations. Methods Retrospective study on patients with acute CSCR. Inclusion criteria were (i) availability of data, sequential OCT and OCT angiography (B scan and en face OCT) every 2 weeks until resolution of SRF or 6 months, whichever is earlier; (ii) single active leak. Exclusion criteria were (i) presence of macular neovascularization or atypical CSCR, (ii) diffuse pigment epitheliopathy, (iii) multiple leaks. Serial en face OCT scans were evaluated and the area ...

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    4. Visual function correlates with foveal slope, retinal and choroidal thickness on optical coherence tomography in type 2 Macular Telangiectasia

      Visual function correlates with foveal slope, retinal and choroidal thickness on optical coherence tomography in type 2 Macular Telangiectasia

      Purpose: To correlate the foveal slope angle (FSA), retinal (RT) and choroidal (CT) thickness measured using optical coherence tomography (OCT) across different stages of type 2 macular telangiectasia (MacTel) with best-corrected visual acuity (BCVA). Methods: A cross-sectional study of 182 gradable quality macular OCT images of 49 patients with type 2 MacTel was carried out. RT was measured on the Spectralis OCT machine from ETDRS (Early Treatment Diabetic Retinopathy Study) retinal thickness map and later used for calculating FSA. RT and CT were measured at 500-µm intervals up to 1500 µm from foveal centre manually. The change in RT ...

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    5. Bacillary layer detachment on optical coherence tomography in exudative age-related macular degeneration

      Bacillary layer detachment on optical coherence tomography in exudative age-related macular degeneration

      Purpose: To report the bacillary layer detachment on optical coherence tomography in exudative age-related macular degeneration. Methods: Retrospective, observational cases. Case descriptions: Two cases of exudative age-related macular degeneration, one diagnosed as polypoidal choroidal vasculopathy following exudative age-related macular degeneration and other as wet age-related macular degeneration with choroidal neovascular membrane showed separation of myoid and ellipsoid zones of photoreceptor layer on optical coherence tomography. This is termed as BALAD. Other associated features noted were the presence of subretinal hyperreflective material, submacular hemorrhage and subretinal fluid. Both cases were treated with monthly intravitreal injections of Inj. Ranibizumab (0.5 mg ...

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    6. Internal limiting membrane detachment in acute central retinal artery occlusion: a novel prognostic sign seen on OCT

      Internal limiting membrane detachment in acute central retinal artery occlusion: a novel prognostic sign seen on OCT

      ackground: To present a series of acute central retinal artery occlusion (CRAO) cases showing internal limiting membrane detachment (ILMD) on optical coherence tomography (OCT) and to describe the possible etiopathogenesis and outcomes associated with it. Methods: Demographic and OCT features of patients with acute CRAO were analysed retrospectively. OCT parameters noted were posterior vitreous opacities, ILMD, inner retinal layer stratification, hyperreflectivity and thickening, cystoid macular edema, neurosensory detachment. Eyes were grouped into Group (1) CRAO with ILMD; Group (2) CRAO with no ILMD. Results: A total of 28 eyes of acute CRAO who had undergone OCT scans at the time ...

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    7. Utility of enface optical coherence tomography in intraocular lymphoma

      Utility of enface optical coherence tomography in intraocular lymphoma

      Purpose: To report the enface optical coherence tomography (OCT) features of intraocular lymphoma. Methods: Retrospective, observational case report Case description A 59-year-old man, a known case of primary testicular carcinoma complained of right eye blurred vision since 1-week. He had undergone systemic intravenous chemotherapy (R-CHOP regime), orchiectomy and external beam radiotherapy for the primary malignancy previously. His right eye vision was 20/30, 6/6 RS. The right eye anterior segment examination was normal. Fundus examination showed vitreous cells 1+ and a large, bumpy, sub retinal dull-yellow lesion sparing the fovea with multiple discrete yellow retinal lesions at the posterior ...

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    8. Study of retinal structural–functional relationship in choroideremia using fundus autofluorescence and optical coherence tomography

      Study of retinal structural–functional relationship in choroideremia using fundus autofluorescence and optical coherence tomography

      Objective The objective of this study was to assess the structural–functional relationship in choroideremia (CHM) patients using optical coherence tomography (OCT) and autofluorescence (AF) images. Methods In this study, 53 eyes of 28 CHM patients were included. Demographic, ocular and clinical fundus features were recorded. Fundus AF and OCT images were analysed. Patients were classified into two groups based on AF features: group 1, CHM patients where the foveal island was present and group 2, CHM patients where the foveal island was absent. Inner and outer retinal layer thicknesses, retinal pigment epithelium (RPE) and subfoveal choroidal thickness (SFCT) were ...

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    9. Association between sleep apnoea risk score and retinal microvasculature using optical coherence tomography angiography

      Association between sleep apnoea risk score and retinal microvasculature using optical coherence tomography angiography

      Purpose To investigate the retinal vessel changes at peripapillary and parafoveal regions using optical coherence tomography angiography in patients with varying obstructive sleep apnoea syndrome (OSAS) risk, identified by the STOP-BANG questionnaire. Design Prospective, hospital-based cross-sectional study. Methods Participants were divided into 3 groups based on the OSAS risk score. Flow areas and vessel densities were calculated at peripapillary and parafoveal regions using optical coherence tomography angiography. Microvasculature changes between the 3 groups and correlation between OSAS risk score and vascular changes were calculated. Results Six hundred and six eyes of 303 patients were included in groups 1 (n=96 ...

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    10. Hyporeflective micro-elevations and irregularity of the ellipsoid layer: 2 novel optical coherence tomography features in commotio retinae

      Hyporeflective micro-elevations and irregularity of the ellipsoid layer: 2 novel optical coherence tomography features in commotio retinae

      Objective To report on the anatomical changes at the macula in patients with commotio retinae (CR) and not accompanied by any other types of traumatic maculopathy. Design Retrospective, observational case series. Participants In this study, individuals with history of blunt ocular trauma and having CR involving the macula without any other type of traumatic maculopathy were included. Methods Participants were evaluated with ophthalmic examination, visual acuity testing, and spectral domain optical coherence tomography (OCT) at presentation and further follow-up visits. Results On colour fundus photography, grey-white retinal discolouration was identified in all 16 patients and 1 patient had accompanying inferior ...

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    11. Structural-functional correlation using adaptive optics, visual fields, optical coherence tomography and multifocal electroretinogram in a case of torpedo maculopathy

      Structural-functional correlation using adaptive optics, visual fields, optical coherence tomography and multifocal electroretinogram in a case of torpedo maculopathy

      A 37-year-old man, diagnosed previously as a 'chorioretinal scar' in the macula, came for follow-up examination at our retina clinic. He had no ocular symptoms. Systemic history was normal. Eye examination revealed vision of 20/20 in both eyes. Anterior segment examination was normal in both eyes. Dilated fundus examination revealed pink and healthy optic nerves with normal physiologic cupping in each eye. Right eye macular examination revealed a classical, torpedo-shaped, hypopigmented chorioretinal lesion. Left eye macula was unremarkable. Peripheral retina was normal in both eyes. Multimodal imaging of the torpedo lesion was done with fundus autofluoroscence, fundus fluorescein angiography ...

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      Mentions: Imagine Eyes
    12. Retinal structural-vascular-functional relationship using optical coherence tomography and optical coherence tomography – angiography in myopia

      Retinal structural-vascular-functional relationship using optical coherence tomography and optical coherence tomography – angiography in myopia

      Background To examine the retinal structure–vascular-function relationship using optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) in myopia. Methods This was a prospective cross-sectional study comprising 86 eyes of 45 individuals with varying axial lengths and spherical equivalents and no posterior segment abnormalities. All eyes underwent optical coherence tomography with the Spectralis SD-OCT and OCTA with RTVue-XR Avanti; Optovue. Individual macular retinal layer thicknesses and flow areas and vessel densities were measured on OCT and OCTA, respectively. Linear correlations were made between the macular layer thicknesses, flow areas and vessel densities with axial length, spherical equivalent and ...

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      Mentions: Visionix
    13. Diagnosis of subretinal neovascularization associated with idiopathic juxtafoveal retinal telangiectasia — fluorescein angiography versus spectral-domain optical coherence tomography — can we choose?

      Diagnosis of subretinal neovascularization associated with idiopathic juxtafoveal retinal telangiectasia — fluorescein angiography versus spectral-domain optical coherence tomography — can we choose?

      Dear Editor We read with great interest the article entitled ”Diagnosis of subretinal neovascularization associated with idiopathic juxtafoveal retinal telangiectasia—fluorescein angiography versus spectral-domain optical coherence tomography by Chhablani J et al. [ 1 ]. This article compares the ability of fundus fluorescein angiography (FFA) and spectral-domain optical coherence tomography (SD-OCT) to diagnose subretinal neovascularization (SRNV) secondary to idiopathic juxtafoveal retinal telangiectasia (IJRT) type 2A, and also highlights the pitfalls of FFA and OCT in detecting and confirming SRNV in cases of IJRT type 2. However we have made the following observations

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    14. Optical coherence tomography and autofluorescence findings in photic maculopathy secondary to distant lightning strike

      Optical coherence tomography and autofluorescence findings in photic maculopathy secondary to distant lightning strike

      Ophthalmic injuries due to lightning occur mainly from direct or indirect transmission of electric charge, resistance-induced heat, or heat-induced shock wave.1 Most reports of lightning-induced maculopathy quote direct or indirect electric transmission as the cause and associate maculopathy with oculofacial injuries and sometimes loss of consciousness.1 - 3 However, a high-voltage electric current can also induce photic retinopathy without contribution from the electric charge.4 We report a case of photic retinopathy caused solely by viewing a lightning strike.

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    1-16 of 16
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    Optical coherence tomography and autofluorescence findings in photic maculopathy secondary to distant lightning strike Diagnosis of subretinal neovascularization associated with idiopathic juxtafoveal retinal telangiectasia — fluorescein angiography versus spectral-domain optical coherence tomography — can we choose? Retinal structural-vascular-functional relationship using optical coherence tomography and optical coherence tomography – angiography in myopia Structural-functional correlation using adaptive optics, visual fields, optical coherence tomography and multifocal electroretinogram in a case of torpedo maculopathy Enhanced depth imaging optical coherence tomography and multicolour imaging features in bilateral isolated choroidal melanocytosis Hyporeflective micro-elevations and irregularity of the ellipsoid layer: 2 novel optical coherence tomography features in commotio retinae Association between sleep apnoea risk score and retinal microvasculature using optical coherence tomography angiography Study of retinal structural–functional relationship in choroideremia using fundus autofluorescence and optical coherence tomography Utility of enface optical coherence tomography in intraocular lymphoma Bacillary layer detachment on optical coherence tomography in exudative age-related macular degeneration Postdoctoral Fellows/Research Scientists at University of Washington, Seattle Perimeter Medical Imaging AI Announces Publication of Peer-Reviewed Journal Article Validating Potential Use of Wide-Field Optical Coherence Tomography (WF-OCT) in Head and Neck Surgeries