1. Articles from Xin Wen

    1-3 of 3
    1. The vascular densities of the macula and optic disc in normal eyes from children by optical coherence tomography angiography

      The vascular densities of the macula and optic disc in normal eyes from children by optical coherence tomography angiography

      Purpose This study aims to describe the variation and characteristics of vessel density (VD) of the macula and optic disc in the normal eyes of children. Methods This was a retrospective study where subjects aged 5–18 years with normal eyes were enrolled. The macula and optic disc were scanned by optical coherence tomography angiography (OCTA). The influences of age, gender, and axial length (AL) on VD were analyzed. Results A total of 71 normal eyes from 71 subjects were enrolled. For the macula, the mean VD of fovea, parafovea, and perifovea at superficial retina and deep retina were 20 ...

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    2. Do microvascular changes occur preceding neural impairment in early-stage diabetic retinopathy? Evidence based on the optic nerve head using optical coherence tomography angiography

      Do microvascular changes occur preceding neural impairment in early-stage diabetic retinopathy? Evidence based on the optic nerve head using optical coherence tomography angiography

      Aims To evaluate the microvascular and neural differences of the optic nerve head (ONH) between type 2 diabetes mellitus (T2DM) subjects and controls. Methods This was a cross-sectional observational study. One hundred and eight eyes of 108 T2DM subjects with or without diabetic retinopathy (DR) (54 preclinical DR and 54 mild-to-moderate DR) were included. Fifty-two eyes of 52 healthy subjects were included as controls. The 4.5-mm Angio Disc scan mode and the ganglion cell complex scan mode were performed with all participants using AngioVue software 2.0 of the optical coherence tomography angiography (OCTA) device. Results Regarding ONH radial ...

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    3. Spectral Domain Optical Coherence Tomography of Vogt-Koyanagi-Harada Disease: Novel Findings and New Insights into the Pathogenesis

      Spectral Domain Optical Coherence Tomography of Vogt-Koyanagi-Harada Disease: Novel Findings and New Insights into the Pathogenesis

      Objective To provide novel spectral domain optical coherence tomography (SD OCT) findings of Vogt-Koyanagi-Harada (VKH) disease as well as new insights into the pathogenesis of this disease. Methods Detailed SD OCT and fluorescein angiography (FA) findings of 18 consecutive VKH patients (11 women and 7 men) from December 2007 to April 2009 who were in acute uveitic stage at presentation were reviewed. All the patients had been followed up for at least 6 months with reevaluation(s) of SD OCT performed in 10 patients. Results Intraretinal cysts were found to be located in various layers of the outer retina. In ...

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    1-3 of 3
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    1. (2 articles) Sun Yat-Sen University
    2. (1 articles) University College London
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    Spectral Domain Optical Coherence Tomography of Vogt-Koyanagi-Harada Disease: Novel Findings and New Insights into the Pathogenesis Do microvascular changes occur preceding neural impairment in early-stage diabetic retinopathy? Evidence based on the optic nerve head using optical coherence tomography angiography The vascular densities of the macula and optic disc in normal eyes from children by optical coherence tomography angiography Deep iterative vessel segmentation in OCT angiography Subretinal Drusenoid Deposits and Photoreceptor Loss Detecting Global and Local Progression of Geographic Atrophy by SD-OCT Imaging Ultra-high-resolution SD-OCM imaging with a compact polarization-aligned 840 nm broadband combined-SLED source Sparse Domain Gaussianization for Multi-variate Statistical Modeling of Retinal OCT Images Optical reflectance contrast of micro- and nano-structures revealed with intravital micro-OCT (Thesis) In vivo optical biopsy of choroidal osteoma: a swept source optical coherence tomography–based tumor characterization Morphological changes in intraretinal microvascular abnormalities after anti-VEGF therapy visualized on optical coherence tomography angiography SD-OCT peripapillary nerve fibre layer and ganglion cell complex parameters in glaucoma: principal component analysis Accuracy of optical coherence tomography for diagnosing glaucoma: an overview of systematic reviews