1. Articles from Martine Mauget-Faÿsse

    1-11 of 11
    1. Morphological Predictive Features on Spectral-Domain Optical Coherence Tomography for Visual Outcomes in Neovascular Age-Related Macular Degeneration Treated with Ranibizumab

      Morphological Predictive Features on Spectral-Domain Optical Coherence Tomography for Visual Outcomes in Neovascular Age-Related Macular Degeneration Treated with Ranibizumab

      Purpose . To identify spectral-domain optical coherence tomography (SD-OCT) predictive morphological features for the outcome of Ranibizumab therapy for neovascular age-related macular degeneration (AMD). Methods . This is a retrospective multicentric study that involved 64 eyes with naïve AMD. Patients who received three monthly intravitreal injections of Ranibizumab were stratified into (1) “responders” [≥ 5 letters gain on Early Treatment Diabetic Retinopathy Study (ETDRS) scale] and (2) “nonresponders” (< 5 letters gain). Best-corrected visual acuity (BCVA) and SD-OCT morphological features were compared at baseline and one month after three consecutive injections of Ranibizumab. Univariate and multivariate analyses were carried out to correlate these ...

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    2. Dark and white lesions observed in central serous chorioretinopathy on optical coherence tomography angiography

      Dark and white lesions observed in central serous chorioretinopathy on optical coherence tomography angiography

      Dark and white lesions observed in central serous chorioretinopathy on optical coherence tomography angiography Show all authors Flore De Bats , Pierre-Loïc Cornut , Benjamin Wolff , ... First Published March 19, 2018 Research Article Download PDF Article information Abstract Purpose: To describe abnormal dark (hyposignal) and white (hypersignal) lesions observed on optical coherence tomography angiography in central serous chorioretinopathy. Methods: Prospective, multicenter, and descriptive study including patients with active or quiescent central serous chorioretinopathy. All patients had undergone a complete ophthalmic examination. Results: Abnormal dark lesions were detected as “dark spots” and “dark areas” on optical coherence tomography angiography. A “dark spot ...

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    3. Pachychoroid neovasculopathy: aspect on optical coherence tomography angiography

      Pachychoroid neovasculopathy: aspect on optical coherence tomography angiography

      Purpose To describe and interpret the features of pachychoroid neovasculopathy (PNV) using optical coherence tomography angiography (OCTA) technique. Methods This is an observational case series of patients who presented with PNV. Best-corrected visual acuity (BCVA), anterior segment examination, dilated funduscopic examination, infrared and autofluorescence fundus images and spectral-domain optical coherence tomography (SD-OCT; B-scan, ‘en-face’ and OCTA) were carried out for all patients. Choroid thickness was measured using enhanced depth imaging (EDI) mode. Colour fundus photographs, fundus fluorescein angiography (FFA) and indocyanine green angiography (ICGA) were not performed systematically. Optical coherence tomography angiography (OCTA) features of PNV are described and interpreted ...

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    4. Expanded Clinical Spectrum Of Multiple Evanescent White Dot Syndrome With Multimodal Imaging

      Expanded Clinical Spectrum Of Multiple Evanescent White Dot Syndrome With Multimodal Imaging

      Purpose: To evaluate and characterize multiple evanescent white dot syndrome abnormalities with modern multimodal imaging modalities. Methods: This retrospective cohort study evaluated fundus photography, fluorescein angiography, indocyanine green angiography, optical coherence tomography, enhanced depth imaging optical coherence tomography, short-wavelength autofluorescence, and near-infrared autofluorescence.

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    5. "EN FACE" OPTICAL COHERENCE TOMOGRAPHY IMAGING IN TYPE 2 IDIOPATHIC MACULAR TELANGIECTASIA

      "EN FACE" OPTICAL COHERENCE TOMOGRAPHY IMAGING IN TYPE 2 IDIOPATHIC MACULAR TELANGIECTASIA

      Purpose: To comprehensively evaluate the retinal and choroidal changes in eyes with Type 2 idiopathic macular telangiectasia using “en face” and B-scan spectral domain optical coherence tomography (OCT), and to compare their respective contributions to this evaluation. Methods: Eyes with a diagnosis of proliferative or nonproliferative Type 2 macular telangiectasia were prospectively studied. All patients underwent an extensive ophthalmologic examination including biomicroscopic fundus examination, color photography, fundus autofluorescence, fluorescein angiography, B-scan and en face spectral domain OCT. Results: Twenty eyes of 10 patients were included in this study. En face OCT C-scans and conventional B-scans were both able to show ...

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    6. “En-Face” Spectral-Domain Optical Coherence Tomography Findings in Multiple Evanescent White Dot Syndrome

      “En-Face” Spectral-Domain Optical Coherence Tomography Findings in Multiple Evanescent White Dot Syndrome

      Purpose . The recent use of “en-face” enhanced-depth imaging spectral-domain optical coherence tomography (EDI SD-OCT) helps distinguish the retinal layers involved in the physiopathology of multiple evanescent white dot syndrome (MEWDS). Methods . Four patients presenting with MEWDS underwent a comprehensive ocular examination including C-scan (“en-face”) EDI SD-OCT at the initial visit and during follow-up. Results . C-scans combined with the other multimodal imaging enabled the visualization of retinal damage. Acute lesions appeared as diffuse and focal disruptions occurring in the ellipsoid and interdigitation zones. The match between autofluorescence imaging, indocyanine green angiography, and “en-face” OCT helped identify the acute microstructural damages in ...

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    7. Retinal and choroidal changes observed with ‘En face’ enhanced-depth imaging OCT in central serous chorioretinopathy

      Retinal and choroidal changes observed with ‘En face’ enhanced-depth imaging OCT in central serous chorioretinopathy

      Aims To describe retinal and choroidal changes in acute and quiescent central serous chorioretinopathy (CSC) observed with ‘En face’ spectral domain optical coherence tomography (SD OCT) combined with enhanced-depth imaging (EDI). Methods A prospective and descriptive study at the Rothschild Ophthalmologic Foundation (Paris, France) between September 2011 and February 2012. Eyes with a clinical diagnosis of CSC were examined using SD OCT with EDI, fluorescein and indocyanine green angiography. 3D reconstruction of 197 transverse sections with SD OCT, spaced of 30 μ, provided a virtual macular brick through which 496 sections in the coronal plane resulted in a C-scan or En ...

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    8. Retinal and choroidal changes observed with 'En face' enhanced-depth imaging OCT in central serous chorioretinopathy

      Retinal and choroidal changes observed with 'En face' enhanced-depth imaging OCT in central serous chorioretinopathy

      Aims To describe retinal and choroidal changes in acute and quiescent central serous chorioretinopathy (CSC) observed with ‘En face’ spectral domain optical coherence tomography (SD OCT) combined with enhanced-depth imaging (EDI). Methods A prospective and descriptive study at the Rothschild Ophthalmologic Foundation (Paris, France) between September 2011 and February 2012. Eyes with a clinical diagnosis of CSC were examined using SD OCT with EDI, fluorescein and indocyanine green angiography. 3D reconstruction of 197 transverse sections with SD OCT, spaced of 30 μ, provided a virtual macular brick through which 496 sections in the coronal plane resulted in a C-scan or En ...

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    9. RETINAL INNER NUCLEAR LAYER MICROCYSTIC CHANGES IN OPTIC NERVE ATROPHY: A Novel Spectral-Domain OCT Finding

      RETINAL INNER NUCLEAR LAYER MICROCYSTIC CHANGES IN OPTIC NERVE ATROPHY: A Novel Spectral-Domain OCT Finding

      Purpose: Optic atrophy constitutes the final stage in the evolution of optic neuropathy. The aim of this study was to describe the presence of macular microcystic changes or pseudocysts in patients with advanced optic atrophy. Methods: The medical records of 24 patients who had retinal pseudocysts in association with optic atrophy have been analyzed. All patients underwent a complete neuro-ophthalmologic assessment; peripapillary retinal nerve fiber layer thickness and macular screening with spectral-domain optical coherence tomography and optical coherence tomography "en face" imaging analysis were also performed. Results: A total of 36 eyes were included in the study. Patients' mean age ...

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    10. En Face OCT Imaging for the Diagnosis of Outer Retinal Tubulations in Age-Related Macular Degeneration

      En Face OCT Imaging for the Diagnosis of Outer Retinal Tubulations in Age-Related Macular Degeneration

      Purpose. "En face" is an emerging imaging technique derived from spectral domain optical coherence tomography (OCT). It produces frontal sections of retinal layers, also called "C-scan OCT." Outer retinal tubulations (ORTs) in age-related macular degeneration (AMD) are a recent finding evidenced by spectral-domain OCT. The aim of this study is to characterize the morphology of ORT according to the form of AMD, using "en-face" spectral domain OCT. Methods. "En face" OCT imaging was prospectively performed in 26 consecutive eyes with AMD that also had ORT. Results. There were 15 neovascular, 8 atrophic, and 3 eyes with a mixed (fibrotic and ...

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    11. Spectral domain optical coherence tomography evolutive features in acute macular neuroretinopathy

      Spectral domain optical coherence tomography evolutive features in acute macular neuroretinopathy

      Purpose. To demonstrate the usefulness of spectral domain optical coherence tomography (SD-OCT) in investigating the evolution of the retinal outer lesions seen in acute macular neuroretinopathy (AMN). Methods. A 32-year-old woman presented with a 1-day history of paracentral dark spot in the left eye, preceded by a flulike illness. A full ophthalmologic examination, color vision, visual field examination, and conventional imaging of the retina were done. Scanning laser ophthalmoscopic infrared imaging and SD-OCT of the macular region were performed. Results. Best-corrected visual acuity was 20/20 in both eyes. Slit-lamp examination as well as retinal photographs were unrevealing. Scanning laser ...

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    1-11 of 11
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    Spectral domain optical coherence tomography evolutive features in acute macular neuroretinopathy En Face OCT Imaging for the Diagnosis of Outer Retinal Tubulations in Age-Related Macular Degeneration RETINAL INNER NUCLEAR LAYER MICROCYSTIC CHANGES IN OPTIC NERVE ATROPHY: A Novel Spectral-Domain OCT Finding Retinal and choroidal changes observed with 'En face' enhanced-depth imaging OCT in central serous chorioretinopathy Retinal and choroidal changes observed with ‘En face’ enhanced-depth imaging OCT in central serous chorioretinopathy “En-Face” Spectral-Domain Optical Coherence Tomography Findings in Multiple Evanescent White Dot Syndrome "EN FACE" OPTICAL COHERENCE TOMOGRAPHY IMAGING IN TYPE 2 IDIOPATHIC MACULAR TELANGIECTASIA Expanded Clinical Spectrum Of Multiple Evanescent White Dot Syndrome With Multimodal Imaging Pachychoroid neovasculopathy: aspect on optical coherence tomography angiography Dark and white lesions observed in central serous chorioretinopathy on optical coherence tomography angiography Three-dimensional detection and quantification of defects in SiC by optical coherence tomography University of Illinois at Chicago Receives NIH Grant for Functional Tomography of Neurovascular Coupling Interactions in Healthy and Diseased Retinas