1. Articles from Sandra Holgado

    1-6 of 6
    1. OCULAR MANIFESTATIONS OF PORETTI-BOLTSHAUSER SYNDROME: FINDINGS FROM MULTIMODAL IMAGING AND ELECTROPHYSIOLOG

      OCULAR MANIFESTATIONS OF PORETTI-BOLTSHAUSER SYNDROME: FINDINGS FROM MULTIMODAL IMAGING AND ELECTROPHYSIOLOG

      Background/Purpose: Poretti-Boltshauser syndrome is a rare, nonprogressive neurologic syndrome with characteristic cerebellar cysts on neuroimaging due to mutations in LAMA1 . The ophthalmic findings in Poretti-Boltshauser syndrome are not well described. Here, we report the ophthalmic findings from multimodal imaging and electrophysiology of a patient with genetically confirmed Poretti-Boltshauser syndrome . Methods: A 3-year-old boy with confirmed mutations in LAMA1 underwent examination under anesthesia with electroretinography and multimodal imaging including fundus photography, fluorescein angiography , optical coherence tomography , and optical coherence tomography angiography . Results: Dilated fundus examination was notable for retinal vascular anomalies, including a large area of nonperfusion in the temporal ...

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    2. Optical coherence tomography in paediatric glaucoma: time domain versus spectral domain

      Optical coherence tomography in paediatric glaucoma: time domain versus spectral domain

      Background/aims Spectral-domain (SD)- Optical Coherence Tomography (OCT) can track eye movements, has faster acquisition time and higher resolution than time-domain(TD)-OCT. The aim of the study was to assess the utility of SD-OCT in paediatric glaucoma and determine its agreement with TD-OCT. Methods Children who had SD-OCT(Spectralis, Heidelberg-Engineering,Germany) were retrospectively and prospectively identified from Duke paediatric glaucoma clinic. The peripapillary retinal nerve fibre layer (RNFL) and macular thickness and volume (MV) were compared amongst four groups: normal eyes, eyes with physiologic cupping (C:D >0.5 and <0.8, IOP <21), mild glaucomatous eyes (C:D ...

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    3. Optical coherence tomography (OCT) measurements in black and white children with large cup-to-disc ratios

      Optical coherence tomography (OCT) measurements in black and white children with large cup-to-disc ratios
      Children with large optic nerve head cups often pose diagnostic difficulty due to concern over possible glaucoma. This study's purpose was to evaluate optical coherence tomography (OCT) measurement of the peripapillary retinal nerve fiber layer (RNFL) and macular thickness in healthy eyes of black and white children, comparing values for eyes with large cup-to-disc ratios against those with small cup-to-disc ratios (normal controls). Using Stratus OCT (OCT 3) (Carl Zeiss Meditec, Dublin, CA) a fast macular thickness and fast RNFL 3.4 protocol were performed on normal eyes of normal children. Included were children (aged 5-17 years) with normal ...
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    4. Longitudinal reproducibility of optical coherence tomography measurements in children

      Longitudinal reproducibility of optical coherence tomography measurements in children
      Introduction: In healthy eyes of children, optical coherence tomography (OCT) measurements of macular and retinal nerve fiber layer (RNFL) thickness are reproducible within the same day and average RNFL has been correlated with axial length (AL). We evaluated longitudinal reproducibility of OCT measurements in children as AL changed.
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    5. Reproducibility of OCT in children with glaucoma

      Introduction: Optical Coherence Tomography(OCT) has been proven to be a useful clinical tool in the follow-up of adult glaucoma(IOVS2008;49:4886-4892.). Its use in pediatric glaucoma is limited because reproducibility has been assessed only in normal children and on the same visit (AJO,2007;143:484–488). This study's purpose is to evaluate the reproducibility of OCT in children with stable glaucoma in a clinical setting.
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    6. Correlation between Optical Coherence Tomography and glaucomatous optic nerve head damage in children

      Purpose: To compare analysis of macular and nerve fiber layer thickness by optical coherence tomography (OCT), to optic nerve head (ONH) morphology based upon stereophotography. Design: Prospective observational case control series. Methods: Normal and glaucomatous eyes of children (age 4-17 years) were scanned using Stratus OCT (Carl Zeiss Meditec, Dublin, CA). Fast macular and retinal nerve fiber layer (RNFL) thickness map were performed on 372 eyes of 222 children. ONH stereophotographs were taken and evaluated by two masked observers, using a grading system of 0 to 5 based on both cupping ratio and morphology. OCT3 analyses were compared across ONH ...
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    1-6 of 6
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  2. Topics in the News

    1. (5 articles) Duke University
    2. (4 articles) Sanjay G. Asrani
    3. (4 articles) Sharon F. Freedman
    4. (2 articles) Carl Zeiss Meditec
    5. (2 articles) Kyungpook National University
    6. (2 articles) University of Washington
    7. (2 articles) Jeehyun Kim
    8. (2 articles) Ruchire Eranga Wijesinghe
    9. (2 articles) Mansik Jeon
    10. (1 articles) Cynthia A. Toth
    11. (1 articles) Heidelberg Engineering
    12. (1 articles) University of Ulsan
    13. (1 articles) Tokyo Medical & Dental University
    14. (1 articles) University of Toronto
    15. (1 articles) Yasunori Sumi
    16. (1 articles) Ali M. Fard
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    Longitudinal reproducibility of optical coherence tomography measurements in children Optical coherence tomography (OCT) measurements in black and white children with large cup-to-disc ratios Optical coherence tomography in paediatric glaucoma: time domain versus spectral domain OCULAR MANIFESTATIONS OF PORETTI-BOLTSHAUSER SYNDROME: FINDINGS FROM MULTIMODAL IMAGING AND ELECTROPHYSIOLOG A Generic Framework for Fourier-Domain Optical Coherence Tomography Imaging: Software Architecture and Hardware Implementations Vision-Inspection-Synchronized Dual Optical Coherence Tomography for High-Resolution Real-Time Multidimensional Defect Tracking in Optical Thin Film Industry Relative retinal flow velocity detection using optical coherence tomography angiography imaging Comparison of Optical Flow Ratio and Fractional Flow Ratio in Stent-Treated Arteries Immediately After Percutaneous Coronary Intervention Spaceflight Associated Neuro-Ocular Syndrome (SANS): A Systematic Review and Future Directions Retinal Thickness and Microvascular Pattern in Early Parkinson's Disease Artificial Intelligence Algorithms to Diagnose Glaucoma and Detect Glaucoma Progression: Translation to Clinical Practice Multi-directional Morphological Assessment of Single Bacterial Colonies Through Non-invasive Optical Imaging