1. Articles from Giulio Barteselli

    1-16 of 16
    1. In Vivo Evidence of Inner Retinal Neurodegeneration in Retinitis Pigmentosa Using Spectral-Domain Optical Coherence Tomography

      In Vivo Evidence of Inner Retinal Neurodegeneration in Retinitis Pigmentosa Using Spectral-Domain Optical Coherence Tomography

      BACKGROUND AND OBJECTIVE: To investigate the topographic changes in macular ganglion cell inner plexiform layer (GCIPL) thickness in eyes with retinitis pigmentosa (RP). PATIENTS AND METHODS: Forty-five eyes of 25 subjects with RP who underwent spectral-domain optical coherence tomography (SD-OCT) using the Cirrus HD-OCT (Carl Zeiss Meditec, Dublin, CA) were analyzed retrospectively. A control group of 67 eyes of 48 age-matched healthy volunteers was also included for comparison. Average, minimum, and sectoral macular GCIPL, as well as retinal nerve fiber layer (RNFL) and outer retinal (OR) thicknesses, were collected and compared between RP and control groups. RESULTS: The average and ...

      Read Full Article
    2. Comparison Between Full-Depth Imaging Spectral Domain Optical Coherence Tomography and Swept-Source Optical Coherence Tomography

      Comparison Between Full-Depth Imaging Spectral Domain Optical Coherence Tomography and Swept-Source Optical Coherence Tomography

      Purpose: To compare the real-time visualization of vitreoretino-choroidal structures using full-depth imaging (FDI) spectral domain optical coherence tomography (SD-OCT) and swept-source (SS)-OCT. Methods: Foveal scans using both FDI SD-OCT (Heidelberg Spectralis) and SS-OCT (Topcon Deep Range Imaging-OCT-1) were obtained in 40 normal eyes, 40 eyes with macular pathologies, and 40 eyes with glaucoma. Full-depth imaging SD-OCT images were obtained by manually enhancing the vitreoretinal interface first and then the choroid while averaging each OCT B-scan 100 times. Swept-source-OCT images were obtained by averaging each B-scan 96 times. After masking and randomly mixing the original OCT images, two independent physicians ...

      Read Full Article
    3. REAL-TIME FULL-DEPTH VISUALIZATION OF POSTERIOR OCULAR STRUCTURES: Comparison Between Full-Depth Imaging Spectral Domain Optical Coherence Tomography and Swept-Source Optical Coherence Tomography

      REAL-TIME FULL-DEPTH VISUALIZATION OF POSTERIOR OCULAR STRUCTURES: Comparison Between Full-Depth Imaging Spectral Domain Optical Coherence Tomography and Swept-Source Optical Coherence Tomography

      Purpose: To compare the real-time visualization of vitreoretino-choroidal structures using full-depth imaging (FDI) spectral domain optical coherence tomography (SD-OCT) and swept-source (SS)-OCT. Methods: Foveal scans using both FDI SD-OCT (Heidelberg Spectralis) and SS-OCT (Topcon Deep Range Imaging-OCT-1) were obtained in 40 normal eyes, 40 eyes with macular pathologies, and 40 eyes with glaucoma. Full-depth imaging SD-OCT images were obtained by manually enhancing the vitreoretinal interface first and then the choroid while averaging each OCT B-scan 100 times. Swept-source-OCT images were obtained by averaging each B-scan 96 times. After masking and randomly mixing the original OCT images, two independent physicians ...

      Read Full Article
    4. Neurodegeneration in Type 2 Diabetes: Evidence From Spectral-Domain Optical Coherence Tomography

      Neurodegeneration in Type 2 Diabetes: Evidence From Spectral-Domain Optical Coherence Tomography

      Purpose : The purpose of this study was to assess changes in the neural retina in eyes with different stages of diabetic retinopathy (DR) in comparison to age-matched healthy subjects. Methods : Retrospective analysis of spectral-domain optical coherence tomography (SD-OCT) scans of 76 naïve eyes of 62 subjects with diabetes was performed. Key exclusion criteria included presence of diabetic macular edema, any other retinal disease, history of any treatment for DR, or incorrect segmentation of the retinal layers on SD-OCT scans. Eyes from diabetic patients were divided into three groups, including no DR, nonproliferative DR (NPDR), and proliferative DR (PDR). A ...

      Read Full Article
    5. Sudden occurrence of Roth spots and retinal hemorrhages following endoscopic adhesiolysis: an SD-OCT evaluation

      Sudden occurrence of Roth spots and retinal hemorrhages following endoscopic adhesiolysis: an SD-OCT evaluation

      To document the occurrence of Roth spots and retinal hemorrhages by spectral-domain optical coherence tomography (SD-OCT) following endoscopic adhesiolysis for failed back surgery syndrome. Case report. A 47-year-old patient noted progressive and bilateral visual loss immediately after epidural endoscopy and endoscopic adhesiolysis. Funduscopic examination showed multiple Roth spots and retinal hemorrhages at the posterior pole and the retinal midperiphery in both eyes. Spectral-domain optical coherence tomography demonstrated that Roth spots involved the inner retina, while dot hemorrhages involved the outer retina. Most retinal hemorrhages and Roth spots resolved over 6 weeks, with complete functional recovery in both eyes. However, SD-OCT ...

      Read Full Article
    6. Longitudinal modifications of the Ozurdex intravitreal implant as imaged by SD-OCT

      Longitudinal modifications of the Ozurdex intravitreal implant as imaged by SD-OCT

      To describe in vivo longitudinal modifications of the Ozurdex intravitreal implant using spectral-domain optical coherence tomography (SD-OCT) over a 6-month period in an eye treated for retinal vein occlusion (RVO). Case report. An 82-year-old woman with severe macular edema secondary to branch RVO received an Ozurdex intravitreal implant in the left eye. At day 1, SD-OCT showed that the implant was completely filled with highly reflective dexamethasone. At day 30, complete resolution of macular edema on SD-OCT was noted. At day 60, macular edema started to relapse; SD-OCT scans over the implant showed highly reflective borders that appeared irregular and ...

      Read Full Article
    7. Fundus autofluorescence and optical coherence tomography findings in pigmented paravenous retinochoroidal atrophy

      Fundus autofluorescence and optical coherence tomography findings in pigmented paravenous retinochoroidal atrophy

      Pigmented paravenous retinochoroidal atrophy (PPRCA) is a rare ocular disease with unknown etiology characterized by bilateral retinal pigment epithelium (RPE) and choroidal atrophy along retinal veins usually found incidentally during an eye examination. 1 In the past, fluorescein angiography (FA), electrophysiologic tests, and visual field testing have helped in the diagnosis. 1–3 Noninvasive imaging techniques including fundus autofluorescence (FAF) and spectral-domain optical coherence tomography (SD-OCT) are now available to assist retina specialists in the diagnosis of retinal degenerations, dystrophies, 4,5 and also drug toxicity.

      Read Full Article
    8. Optical Coherence Tomography Findings of the Vitreoretinal Interface in Asymptomatic Fellow Eyes of Patients With Acute Posterior Vitreous Detachment

      Optical Coherence Tomography Findings of the Vitreoretinal Interface in Asymptomatic Fellow Eyes of Patients With Acute Posterior Vitreous Detachment

      Purpose: To describe the vitreoretinal interface of the asymptomatic fellow eyes of patients with acute unilateral posterior vitreous detachment (PVD) based on biomicroscopic examination and spectral domain optical coherence tomography. Methods: Sixty-five eyes of 65 consecutive patients with acute unilateral PVD were examined by slit-lamp, indirect ophthalmoscopy, and spectral domain optical coherence tomography. The state of PVD in different retinal locations and premacular pocket were assessed and graded using spectral domain optical coherence tomography. Results: Nine eyes (13.85%) had no PVD, 15 (23.08%) had extrafoveal vitreous separation (Stage 1), 18 (27.69%) had partial foveal vitreous separation (Stage ...

      Read Full Article
      Mentions: UCSD
    9. Safety and Efficacy of Oral Fluorescein Angiography in Detecting Macular Edema in Comparison With Spectral-Domain Optical Coherence Tomography

      Safety and Efficacy of Oral Fluorescein Angiography in Detecting Macular Edema in Comparison With Spectral-Domain Optical Coherence Tomography

      Purpose: To evaluate the safety of oral fluorescein angiography (FA) and to compare its efficacy in detection of macular edema (ME) with spectral-domain optical coherence tomography (SD-OCT). Methods: Results of imaging studies for 1,928 eyes of 1,019 patients who had simultaneously undergone both oral FA and SD-OCT by a confocal laser ophthalmoscope were reviewed. Sensitivity in detecting ME, discrepancy rate, and "kappa" agreement were determined for both the techniques and with eyes stratified by disease diagnosis. Results: No allergic reactions occurred after oral FA. Mild gastric discomfort was noted in <1% of the patients; 1,840 eyes (95 ...

      Read Full Article
    10. Combined Depth Imaging Technique on Spectral-Domain Optical Coherence Tomography

      Combined Depth Imaging Technique on Spectral-Domain Optical Coherence Tomography

      Purpose To describe a technique to obtain combined images of vitreoretinal and choroidal structures using spectral-domain (SD) optical coherence tomography (OCT) and to evaluate applicability in normal eyes and limitations in eyes with cataract. Design Prospective, observational case series. Methods Three different foveal scans, including conventional SD OCT, enhanced depth imaging OCT and the novel method called combined depth imaging (CDI) OCT, were obtained in 42 eyes of healthy volunteers and in 26 eyes with cataract using the Heidelberg Spectralis HRA (Heidelberg Engineering). The CDI OCT images were obtained manually using an image modification process that enhances the vitreoretinal interface ...

      Read Full Article
    11. Influence of scanning density on macular choroidal volume measurement using spectral-domain optical coherence tomography

      Influence of scanning density on macular choroidal volume measurement using spectral-domain optical coherence tomography

      Background To evaluate the impact of scanning density on macular choroidal volume measurement using spectral-domain optical coherence tomography (SD-OCT). Methods Thirty eyes of normal subjects underwent consecutive raster choroidal scanning protocols using SD-OCT in enhanced-depth imaging mode. Manual choroidal segmentation was performed using the built-in automated retinal segmentation software to obtain five analyses with different inter-scan distances, including inter-scan distances of 30 μm, 60 μm, 120 μm, 240 μm, and 480 μm. The built-in software of the device automatically generated the choroidal thickness and volume map in the similar manner as for the retinal volume map, using the standardized Early ...

      Read Full Article
    12. Choroidal Volume Variations with Age, Axial Length, and Sex in Healthy Subjects: A Three-Dimensional Analysis

      Choroidal Volume Variations with Age, Axial Length, and Sex in Healthy Subjects: A Three-Dimensional Analysis

      Purpose To demonstrate the 3-dimensional choroidal volume distribution in healthy subjects using enhanced depth imaging (EDI) spectral-domain optical coherence tomography (SD-OCT) and to evaluate its association with age, sex, and axial length. Design Retrospective case series. Participants A total of 176 eyes from 114 subjects with no retinal or choroidal disease. Methods The EDI SD-OCT imaging studies of healthy patients who had undergone a 31-raster scanning protocol on a commercial SD-OCT device were reviewed. Manual segmentation of the choroid was performed by 2 retinal specialists. A macular choroidal volume map and 3-dimensional topography were automatically created by the built-in software ...

      Read Full Article
      Mentions: UCSD
    13. Repeatability and reproducibility of manual choroidal volume measurements using enhanced depth imaging optical coherence tomography

      Repeatability and reproducibility of manual choroidal volume measurements using enhanced depth imaging optical coherence tomography

      Purpose: To evaluate the repeatability and reproducibility of manual choroidal volume (CV) measurements on spectral-domain optical coherence tomography (SD-OCT) using enhanced depth imaging (EDI). Methods: Sixty eyes of 32 patients with or without any ocular chorio-retinal diseases were enrolled prospectively. Thirty-one choroidal scans were performed on each eye centered at the fovea using a raster protocol. Two masked observers demarcated choroidal boundaries using the built-in automated retinal segmentation software on two separate sessions. The observers were masked to each other's and their own previous readings. A standardized grid centered on the fovea was positioned automatically by the Spectralis OCT ...

      Read Full Article
      Mentions: UCSD
    1-16 of 16
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Topics in the News

    1. (8 articles) UCSD
    2. (5 articles) University of Milan
    3. (2 articles) Topcon Medical Systems
    4. (2 articles) Heidelberg Engineering
    5. (1 articles) University of Southern California
    6. (1 articles) L V Prasad Eye Institute
    7. (1 articles) Carl Zeiss Meditec
    8. (1 articles) San Raffaele Scientfic Institute
    9. (1 articles) Carl Zeiss Meditec
  3. Popular Articles

  4. Picture Gallery

    Repeatability and reproducibility of manual choroidal volume measurements using enhanced depth imaging optical coherence tomography Choroidal Volume Variations with Age, Axial Length, and Sex in Healthy Subjects: A Three-Dimensional Analysis Influence of scanning density on macular choroidal volume measurement using spectral-domain optical coherence tomography Combined Depth Imaging Technique on Spectral-Domain Optical Coherence Tomography Safety and Efficacy of Oral Fluorescein Angiography in Detecting Macular Edema in Comparison With Spectral-Domain Optical Coherence Tomography Optical Coherence Tomography Findings of the Vitreoretinal Interface in Asymptomatic Fellow Eyes of Patients With Acute Posterior Vitreous Detachment Fundus autofluorescence and optical coherence tomography findings in pigmented paravenous retinochoroidal atrophy Sudden occurrence of Roth spots and retinal hemorrhages following endoscopic adhesiolysis: an SD-OCT evaluation Neurodegeneration in Type 2 Diabetes: Evidence From Spectral-Domain Optical Coherence Tomography Morphological Appearance of Type III Dalen-Fuchs Nodules by SD-OCT Intraoperative Optical Coherence Tomography in Idiopathic Macular Epiretinal Membrane Surgery Quantitative approaches in multimodal fundus imaging: State of the art and future perspectives