1. Articles from Arlie G. Capps

    1-6 of 6
    1. Comparison of amplitude-decorrelation, speckle-variance and phase-variance OCT angiography methods for imaging the human retina and choroid

      Comparison of amplitude-decorrelation, speckle-variance and phase-variance OCT angiography methods for imaging the human retina and choroid

      We compared the performance of three OCT angiography (OCTA) methods: speckle variance, amplitude decorrelation and phase variance for imaging of the human retina and choroid. Two averaging methods, split spectrum and volume averaging, were compared to assess the quality of the OCTA vascular images. All data were acquired using a swept-source OCT system at 1040 nm central wavelength, operating at 100,000 A-scans/s. We performed a quantitative comparison using a contrast-to-noise (CNR) metric to assess the capability of the three methods to visualize the choriocapillaris layer. For evaluation of the static tissue noise suppression in OCTA images we proposed ...

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    2. Feature Of The Week 02/01/2015: Progress on Developing Adaptive Optics OCT for In Vivo Retinal Imaging: Monitoring and Correction of Eye Motion Artifacts (with Audio Narration)

      Feature Of The Week 02/01/2015: Progress on Developing Adaptive Optics OCT for In Vivo Retinal Imaging: Monitoring and Correction of Eye Motion Artifacts (with Audio Narration)

      Recent progress in retinal image acquisition techniques, including optical coherence tomography (OCT) and scanning laser ophthalmoscopy (SLO), combined with improved performance of adaptive optics (AO) instrumentation, has resulted in improvement in the quality of in vivo images of cellular structures in the human retina. Here, we present a short review of progress on developing AO-OCT instruments. Despite significant progress in imaging speed and resolution, eye movements present during acquisition of a retinal image with OCT introduce motion artifacts into the image, complicating analysis and registration. This effect is especially pronounced in high-resolution datasets acquired with AO-OCT instruments. Several retinal tracking ...

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    3. Progress on Developing Adaptive Optics-Optical Coherence Tomography for In Vivo Retinal Imaging: Monitoring and Correction of Eye Motion Artifacts

      Progress on Developing Adaptive Optics-Optical Coherence Tomography for In Vivo Retinal Imaging: Monitoring and Correction of Eye Motion Artifacts

      Recent progress in retinal image acquisition techniques, including optical coherence tomography (OCT) and scanning laser ophthalmoscopy (SLO), combined with improved performance of adaptive optics (AO) instrumentation, has resulted in improvement in the quality of in vivo images of cellular structures in the human retina. Here, we present a short review of progress on developing AO-OCT instruments. Despite significant progress in imaging speed and resolution, eye movements present during acquisition of a retinal image with OCT introduce motion artifacts into the image , complicating analysis and registration. This effect is especially pronounced in high-resolution datasets acquired with AO-OCT instruments. Several retinal tracking ...

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    4. Progress on Developing Adaptive Optics–Optical Coherence Tomography for In Vivo Retinal Imaging: Monitoring and Correction of Eye Motion Artifacts

      Progress on Developing Adaptive Optics–Optical Coherence Tomography for In Vivo Retinal Imaging: Monitoring and Correction of Eye Motion Artifacts

      Recent progress in retinal image acquisition techniques, including optical coherence tomography (OCT) and scanning laser ophthalmoscopy (SLO), combined with improved performance of adaptive optics (AO) instrumentation, has resulted in improvement in the quality of in vivo images of cellular structures in the human retina. Here, we present a short review of progress on developing AO-OCT instruments. Despite significant progress in imaging speed and resolution, eye movements present during acquisition of a retinal image with OCT introduce motion artifacts into the image, complicating analysis and registration. This effect is especially pronounced in high-resolution datasets acquired with AO-OCT instruments. Several retinal tracking ...

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    5. Multimodal assessment of microscopic morphology and retinal function in patients with geographic atrophy

      Multimodal assessment of microscopic morphology and retinal function in patients with geographic atrophy

      Purpose: To correlate retinal function and visual sensitivity with retinal morphology revealed by ultrahigh-resolution imaging with adaptive optics -optical coherence tomography (AO-OCT), on patients with geographic atrophy. Methods: Five eyes from five subjects were tested [4 with geographic atrophy (66.3 ± 6.4 years, mean±1S.D.) and 1 normal (61 years)]. Photopic and scotopic multifocal electroretinograms (mfERGs) were recorded. Visual fields were assessed with microperimetry (mP) combined with a scanning laser ophthalmoscope for high-resolution confocal retinal fundus imaging. The eye tracker of the microperimeter identified the preferred retinal locus that was then used as a reference for precise targeting ...

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    6. In-vivo imaging of inner retinal cellular morphology with adaptive optics-optical coherence tomography: challenges and possible solutions

      In-vivo imaging of inner retinal cellular morphology with adaptive optics-optical coherence tomography: challenges and possible solutions

      Recent progress in retinal image acquisition techniques, including optical coherence tomography (OCT) and scanning laser ophthalmoscopy (SLO), combined with improved performance of adaptive optics (AO) instrumentation, has resulted in improvement in the quality of in vivo images of cellular structures in the outer layers of the human retina. Despite the significant progress in imaging cone and rod photoreceptor mosaics, visualization of cellular structures in the inner retina has been achieved only with extrinsic contrast agents that have not been approved for use with humans. In this paper we describe the main limiting factors in visualizing inner retinal cells and the ...

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    1-6 of 6
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  2. Topics in the News

    1. (6 articles) John S. Werner
    2. (6 articles) Robert J. Zawadzki
    3. (6 articles) Arlie G. Capps
    4. (5 articles) UC Davis
    5. (4 articles) Dae Yu Kim
    6. (4 articles) Bernd Hamann
    7. (1 articles) Lawrence Livermore National Laboratory
    8. (1 articles) Anjul M. Davis
    9. (1 articles) Scot S. Olivier
    10. (1 articles) Steven M. Jones
    11. (1 articles) Sunnybrook Health Sciences Centre
    12. (1 articles) Harvard University
    13. (1 articles) Kyoto University Graduate School of Medicine
    14. (1 articles) Ryerson University
    15. (1 articles) University of Toronto
    16. (1 articles) Nanjing University of Science and Technology
    17. (1 articles) Joel Ramjist
    18. (1 articles) Akitaka Tsujikawa
    19. (1 articles) Lida P. Hariri
    20. (1 articles) Victor X. D. Yang
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    In-vivo imaging of inner retinal cellular morphology with adaptive optics-optical coherence tomography: challenges and possible solutions Multimodal assessment of microscopic morphology and retinal function in patients with geographic atrophy Progress on Developing Adaptive Optics–Optical Coherence Tomography for In Vivo Retinal Imaging: Monitoring and Correction of Eye Motion Artifacts Progress on Developing Adaptive Optics-Optical Coherence Tomography for In Vivo Retinal Imaging: Monitoring and Correction of Eye Motion Artifacts Feature Of The Week 02/01/2015: Progress on Developing Adaptive Optics OCT for In Vivo Retinal Imaging: Monitoring and Correction of Eye Motion Artifacts (with Audio Narration) Comparison of amplitude-decorrelation, speckle-variance and phase-variance OCT angiography methods for imaging the human retina and choroid In Vivo and Ex Vivo Microscopy: Moving Toward the Integration of Optical Imaging Technologies Into Pathology Practice Recognition of calcified neoatherosclerosis Spectral domain optical coherence tomography as an adjunctive tool for screening Behçet uveitis Thickness of the Macula, Retinal Nerve Fiber Layer, and Ganglion Cell-inner Plexiform Layer in the Macular Hole: The Repeatability Study of Spectral-domain Optical Coherence Tomography Line-field confocal time-domain optical coherence tomography with dynamic focusing Evaluation of vascular changes in intermediate uveitis and retinal vasculitis using swept-source wide-field optical coherence tomography angiography