1. Articles from Meda L. Negrutiu

    1-11 of 11
    1. Optical imaging of oral pathological tissue using optical coherence tomography and synchrotron radiation computed microtomography

      Optical imaging of oral pathological tissue using optical coherence tomography and synchrotron radiation computed microtomography

      The efforts aimed at early diagnosis of oral cancer should be prioritized towards developing a new screening instrument, based on optical coherence tomography (OCT), to be used directly intraorally, able to perform a fast, real time, 3D and non-invasive diagnosis of oral malignancies. The first step in this direction would be to optimize the OCT image interpretation of oral tissues. Therefore we propose plastination as a tissue preparation method that better preserves three-dimensional structure for study by new optical imaging techniques. The OCT and the synchrotron radiation computed microtomography (micro-CT) were employed for tissue sample analyze. For validating the OCT ...

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    2. Bone regeneration assessment by optical coherence tomography and MicroCT synchrotron radiation

      Bone regeneration assessment by optical coherence tomography and MicroCT synchrotron radiation

      Bone grafting is a commonly performed surgical procedure to augment bone regeneration in a variety of orthopaedic and maxillofacial procedures, with autologous bone being considered as the "gold standard" bone-grafting material, as it combines all properties required in a bone-graft material: osteoinduction (bone morphogenetic proteins – BMPs - and other growth factors), osteogenesis (osteoprogenitor cells) and osteoconduction (scaffold). The problematic elements of bone regenerative materials are represented by their quality control methods, the adjustment of the initial bone regenerative material, the monitoring (noninvasive, if possible) during their osteoconduction and osteointegration period and biomedical evaluation of the new regenerated bone. One of the ...

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    3. Imagistic evaluation of direct dental restoration: en face OCT versus SEM and microCT

      Imagistic evaluation of direct dental restoration: en face OCT versus SEM and microCT
      There are several methods known which are used to assess the quality of direct dental restorations, but most of them are invasive. These lead to the destruction of the probes and often no conclusion could be drawn in respect to the existence of any microleakage in the investigated areas of interest. Optical tomographic techniques are of particular importance in the medical imaging field, because these techniques can provide non-invasive diagnostic images. Using an en-face version of OCT, we have recently demonstrated real time thorough evaluation of quality of dental fillings. The purpose of this in vitro study was to validate ...
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    4. SEM and microCT validation for en face OCT imagistic evaluation of endodontically treated human teeth

      SEM and microCT validation for en face OCT imagistic evaluation of endodontically treated human teeth

      Successful root canal treatment is based on diagnosis, treatment planning, knowledge of tooth anatomy, endodontic access cavity design, controlling the infection by thorough cleaning and shaping, methods and materials used in root canal obturation. An endodontic obturation must be a complete, three-dimensional filling of the root canal system, as close as possible to cemento-dentinal junction, without massive overfilling or underfilling. There are several known methods which are used to assess the quality of the endodontic sealing, but most are invasive. These lead to the destruction of the samples and often no conclusion could be drawn in respect to the existence ...

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    5. Morphological characterization of dental prostheses interfaces using optical coherence tomography

      Morphological characterization of dental prostheses interfaces using optical coherence tomography
      Fixed partial prostheses as integral ceramic, polymers, metal-ceramic or metal-polymers bridges are mainly used in the frontal part of the dental arch (especially the integral bridges). They have to satisfy high stress as well as esthetic requirements. The masticatory stress may induce fractures of the bridges. These may be triggered by initial materials defects or by alterations of the technological process. The fractures of these bridges lead to functional, esthetic and phonetic disturbances which finally render the prosthetic treatment inefficient. Dental interfaces represent one of the most significant aspects in the strength of the dental prostheses under the masticatory load ...
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    6. Adhesive improvement in optical coherence tomography combined with confocal microscopy for class V cavities investigations

      Adhesive improvement in optical coherence tomography combined with confocal microscopy for class V cavities investigations
      The purpose of this study is to present a non invasive method for the marginal adaptation evaluation in class V composite restorations. Standardized class V cavities prepared in human extracted teeth were filled with composite resin (Premise, Kerr). The specimens were thermocycled. The interfaces were examined by Optical Coherence Tomography (OCT) combined with confocal microscopy and fluorescence. The optical configuration uses two single mode directional couplers with a superluminiscent diode as the source at 1300 nm. The scanning procedure is similar to that used in any confocal microscope, where the fast scanning is en-face (line rate) and the depth scanning ...
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    7. Optical coherence tomography and confocal microscopy investigations of dental structures and restoration materials

      Nowadays, optical tomographic techniques are of particular importance in the medical imaging field, because these techniques can provide non-invasive diagnostic images. The present study evaluates the potential of en-face optical coherence tomography (OCT) as a possible non-invasive high resolution imaging method in supplying the necessary information on the quality of dental hard tissues and defects of dental restorative materials. Teeth after several treatment methods are imaged in order to asses the material defects and micro-leakage of tooth-filling interface as well as to evaluate the quality of dental hard tissue. C-scan and B-scan OCT images as well as confocal images are ...
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    8. Fibres reinforced dentures investigated with en-face optical coherence tomography

      Meda L. Negrutiu, Cosmin Sinescu, Michael Hughes et al. The complete dentures are currently made using different technologies. In order to avoid deficiencies of the prostheses made using the classical technique, several alternative procedures have been devised. In order to enhance the mechanical strength, complete denture bases are reinforced with fibres ... [Proc. SPIE Int. Soc. Opt. Eng. 6991, 69911U (2008)] published Fri May 2, 2008.
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    9. Root canal filling evaluation using optical coherence tomography

      Meda L. Negrutiu, Cosmin Sinescu, Michael Hughes et al. The root canal fillings are destined to seal the root canal especially in the apical areea. Invasive techniques are known which are used to assess the quality of the seal. These lead to the destruction of the probes and often no conclusion could be drawn in respect to the existence of any microleaka ... [Proc. SPIE Int. Soc. Opt. Eng. 6991, 69911T (2008)] published Fri May 2, 2008.
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    10. Investigation of bracket bonding for orthodontic treatments using en-face optical coherence tomography

      Cosmin Sinescu, Meda L. Negrutiu, Michael Hughes et al. Despite good diagnosis and treatment planning, orthodontic treatment can fail if bonding fails. It is now common practice to address the aesthetic appearance of patients using aesthetic brackets instead of metal ones. Therefore, bonding aesthetic brackets has become an issue for orthodontists today. ... [Proc. SPIE Int. Soc. Opt. Eng. 6991, 69911M (2008)] published Fri May 2, 2008.
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    11. Complete denture analyzed by optical coherence tomography

      Meda L. Negrutiu, Cosmin Sinescu, Carmen Todea et al. The complete dentures are currently made using different technologies. In order to avoid deficiencies of the prostheses made using the classical technique, several alternative systems and procedures were imagined, directly related to the material used and also to the manufacturing technology. Thus, ... [Proc. SPIE Int. Soc. Opt. Eng. 6843, 68430R (2008)] published Mon Feb 11, 2008.
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    1-11 of 11
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  2. Topics in the News

    1. (11 articles) University of Kent
    2. (11 articles) Adrian G. Podoleanu
    3. (11 articles) Cosmin Sinescu
    4. (10 articles) Victor Babes University of Medicine and Pharmacy
    5. (7 articles) Adrian Bradu
    6. (3 articles) State University of New York at Buffalo
    7. (2 articles) Adrian Manescu
    8. (2 articles) Virgil-Florin Duma
    9. (2 articles) George M. Dobre
    10. (1 articles) Academic Medical Center at the University of Amsterdam
    11. (1 articles) Jichi Medical University
    12. (1 articles) University of Milan
    13. (1 articles) Bern University Hospital
    14. (1 articles) Capital Medical University
    15. (1 articles) Nanjing University of Science and Technology
    16. (1 articles) Martin S. Zinkernagel
    17. (1 articles) Junya Ako
    18. (1 articles) Frank D. Verbraak
    19. (1 articles) Giovanni Staurenghi
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    Morphological characterization of dental prostheses interfaces using optical coherence tomography Adhesive improvement in optical coherence tomography combined with confocal microscopy for class V cavities investigations SEM and microCT validation for en face OCT imagistic evaluation of endodontically treated human teeth Imagistic evaluation of direct dental restoration: en face OCT versus SEM and microCT Bone regeneration assessment by optical coherence tomography and MicroCT synchrotron radiation Correlation between optical coherence tomography, multifocal electroretinogram findings and visual acuity in diabetic macular edema Ciliary body length revisited by anterior segment optical coherence tomography: implications for safe access to the pars plana for intravitreal injections Evaluation of retinal vascular structure after epiretinal membrane surgery by optical coherence tomography angiography Bivalirudin vs. Heparin on Radial Artery Thrombosis during Transradial Coronary Intervention: An Optical Coherence Tomography Study Superficial Calcification With Rotund Shape Is Associated With Carotid Plaque Rupture: An Optical Coherence Tomography Study Longitudinal retinal layer changes in preclinical Alzheimer’s disease Clinical expert consensus document on rotational atherectomy from the Japanese association of cardiovascular intervention and therapeutics