1. Articles from Lukasz Koltowski

    1-4 of 4
    1. Second generation, sirolimus‐eluting, bioresorbable Tyrocore scaffold implantation in patients with ST‐segment elevation myocardial infarction: Baseline OCT and 30‐day clinical outcomes – A Fantom Stemi pilot study

      Second generation, sirolimus‐eluting, bioresorbable Tyrocore scaffold implantation in patients with ST‐segment elevation myocardial infarction: Baseline OCT and 30‐day clinical outcomes – A Fantom Stemi pilot study

      Background There is paucity of data on acute performance of Fantom (REVA Medical, CA), a second generation sirolimus‐eluting bioresorbable scaffold (BRS), in ST‐segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention. The aim of this study was to evaluate safety and efficacy of the Fantom BRS in the acute setting of STEMI characterized by thrombogenic milieu. Methodology Ten STEMI patients treated with a sirolimus‐eluting Fantom BRS were enrolled into prospective, observational study. The scaffold sizing, positioning, and optimization were optical coherence tomography (OCT) guided. The primary end‐point was the device‐oriented composite endpoint (DOCE ...

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    2. Rational and Design of the European Randomized Optical Coherence Tomography Optimized Bifurcation Event Reduction Trial (OCTOBER)

      Rational and Design of the European Randomized Optical Coherence Tomography Optimized Bifurcation Event Reduction Trial (OCTOBER)

      Background Percutaneous coronary intervention (PCI) in complex bifurcation lesions is prone to suboptimal implantation results and is associated with increased risk of subsequent clinical events. Angiographic ambiguity is high during bifurcation stenting but it is unknown if procedural guidance by intravascular optical coherence tomography (OCT) improves clinical outcome. Methods and design OCTOBER is a randomized, investigator initiated, multi-center trial aimed to show superiority of OCT guided stent implantation compared to standard angiographic guided implantation in bifurcation lesions. The primary outcome measure is a two-year composite endpoint of cardiac death, target lesion myocardial infarction, and ischemia driven target lesion revascularization. The ...

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    3. Intravascular imaging of coronary artery disease: recent progress and future directions

      Intravascular imaging of coronary artery disease: recent progress and future directions

      Although coronary angiography represents a well established diagnostic modality for percutaneous coronary intervention guidance, recent intravascular imaging techniques, such as intravascular ultrasound, optical coherence tomography (OCT) and near-infrared spectroscopy offer advantages on top of angiography, enhancing the efficacy of lesion evaluation and potentially optimizing the acute and long-term percutaneous coronary intervention outcomes. In addition, recently new generation imaging options have emerged, such as high-definition intravascular ultrasound, polarization-sensitive OCT, intravascular photoacoustic imaging and ultrafast heartbeat OCT. In this review, the current data on the available intravascular imaging techniques, their clinical utility as well as recent technical progresses will be summarized.

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    4. Consensus Standards for Acquisition, Measurement, and Reporting of Intravascular Optical Coherence Tomography Studies: A Report From the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation

      Consensus Standards for Acquisition, Measurement, and Reporting of Intravascular Optical Coherence Tomography Studies: A Report From the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation

      Objectives: The purpose of this document is to make the output of the International Working Group for Intravascular Optical Coherence Tomography (IWG-IVOCT) Standardization and Validation available to medical and scientific communities, through a peer-reviewed publication, in the interest of improving the diagnosis and treatment of patients with atherosclerosis, including coronary artery disease.Background: Intravascular optical coherence tomography (IVOCT) is a catheter-based modality that acquires images at a resolution of 10 μm, enabling visualization of blood vessel wall microstructure in vivo at an unprecedented level of detail. IVOCT devices are now commercially available worldwide, there is an active user base, and ...

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    1-4 of 4
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    Consensus Standards for Acquisition, Measurement, and Reporting of Intravascular Optical Coherence Tomography Studies: A Report From the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation Intravascular imaging of coronary artery disease: recent progress and future directions Rational and Design of the European Randomized Optical Coherence Tomography Optimized Bifurcation Event Reduction Trial (OCTOBER) Second generation, sirolimus‐eluting, bioresorbable Tyrocore scaffold implantation in patients with ST‐segment elevation myocardial infarction: Baseline OCT and 30‐day clinical outcomes – A Fantom Stemi pilot study Optical coherence tomography angiography of foveal neovascularisation in proliferative diabetic retinopathy Treating port wine stain birthmarks using dynamic optical coherence tomography-guided setting Repeatability of quantitative measurements of retinal layers with SD-OCT and agreement between vertical and horizontal scan protocols in healthy eyes Perimeter Medical Imaging Closes Oversubscribed $C4.4M Financing Time-domain optical coherence tomography system based on moving-optical-wedge interferometer ML and AI: At the Forefront of Ophthalmology Automated 3D Optical Coherence Tomography to Elucidate Biofilm Morphogenesis Over Large ... Culprit lesion morphology in young patients with st-segment elevated myocardial infarction: A clinical, angiographic and optical coherence tomography study