1. Articles from Emmanuel Coron

    1-3 of 3
    1. Advanced precancerous lesions in the lower oesophageal mucosa: High-grade dysplasia and intramucosal carcinoma in Barrett's oesophagus

      Advanced precancerous lesions in the lower oesophageal mucosa: High-grade dysplasia and intramucosal carcinoma in Barrett's oesophagus

      Adenocarcinoma developed in Barrett's oesophagus is a tumour with an increasing incidence and still a poor prognosis. The only marker that can be used for surveillance remains dysplasia (intraepithelial neoplasia), especially when it is high-grade, that precedes intramucosal carcinoma. New forms of dysplasia have been described in complement to the classical intestinal type (foveolar dysplasia, basal crypt dysplasia). High-grade dysplasia and intramucosal carcinoma are diagnosed on biopsies taken during endoscopy. Standard endoscopy is now challenged by various techniques that represent recent major technical improvements (chromoendoscopy, virtual chromoendoscopy, optical frequency domain imaging, confocal laser endomicroscopy). In numerous cases, high-grade dysplasia ...

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    2. Interobserver Agreement for the Detection of Barrett’s Esophagus with Optical Frequency Domain Imagin

      Interobserver Agreement for the Detection of Barrett’s Esophagus with Optical Frequency Domain Imagin

      Background Optical frequency domain imaging (OFDI) is a second-generation form of optical coherence tomography (OCT) providing comprehensive cross-sectional views of the distal esophagus at a resolution of ~7 μm. Aim Using validated OCT criteria for squamous mucosa, gastric cardia mucosa, and Barrett’s esophagus (BE), the objective of this study was to determine the inter- and intra-observer agreements by a large number of OFDI readers for differentiating these tissues. Methods OFDI images were obtained from nine subjects undergoing screening and surveillance for BE. Sixty-four OFDI image regions of interest were randomly selected for review. A training set of 19 images ...

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    3. Dual-modality fluorescence and full-field optical coherence microscopy for biomedical imaging applications

      Dual-modality fluorescence and full-field optical coherence microscopy for biomedical imaging applications

      Full-field optical coherence microscopy (FFOCM) is a high-resolution interferometric technique that is particularly attractive for biomedical imaging. Here we show that combining it with structured illumination fluorescence microscopy on one platform can increase its versatility since it enables co-localized registration of optically sectioned reflectance and fluorescence images. To demonstrate the potential of this dual modality, a fixed and labeled mouse retina was imaged. Results showed that both techniques can provide complementary information and therefore the system could potentially be useful for biomedical imaging applications.

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    1-3 of 3
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    1. (2 articles) Harvard University
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    Dual-modality fluorescence and full-field optical coherence microscopy for biomedical imaging applications Interobserver Agreement for the Detection of Barrett’s Esophagus with Optical Frequency Domain Imagin Advanced precancerous lesions in the lower oesophageal mucosa: High-grade dysplasia and intramucosal carcinoma in Barrett's oesophagus Compensating spatially dependent dispersion in visible light OCT Imaging of Epiretinal Membranes Using En Face Widefield Swept-Source Optical Coherence Tomography Optical Coherence Tomography Angiography of RPGR-Associated Retinitis Pigmentosa Suggests Foveal Avascular Zone is a Biomarker for Vision Loss Impact of MEditerranean Diet, Inflammation and Microbiome After an Acute Coronary Syndrome Optical Coherence Tomography for Assessment of the Treatment Effect of Tiotropium in Early Stage of COPD Association of endothelial function with thin-cap fibroatheroma as assessed by optical coherence tomography in patients with acute coronary syndromes System Engineer Opening at Heidelberg Engineering in Lübeck Germany Refractory radiation-induced coronary artery disease: mapping the path and guiding treatment with optical coherence tomography Architecture evaluation of the main clear corneal incisions in femtosecond laser-assisted cataract surgery by optical coherence tomography imaging