1. Articles from Emmanuel Coron

    1-3 of 3
    1. Advanced precancerous lesions in the lower oesophageal mucosa: High-grade dysplasia and intramucosal carcinoma in Barrett's oesophagus

      Advanced precancerous lesions in the lower oesophageal mucosa: High-grade dysplasia and intramucosal carcinoma in Barrett's oesophagus

      Adenocarcinoma developed in Barrett's oesophagus is a tumour with an increasing incidence and still a poor prognosis. The only marker that can be used for surveillance remains dysplasia (intraepithelial neoplasia), especially when it is high-grade, that precedes intramucosal carcinoma. New forms of dysplasia have been described in complement to the classical intestinal type (foveolar dysplasia, basal crypt dysplasia). High-grade dysplasia and intramucosal carcinoma are diagnosed on biopsies taken during endoscopy. Standard endoscopy is now challenged by various techniques that represent recent major technical improvements (chromoendoscopy, virtual chromoendoscopy, optical frequency domain imaging, confocal laser endomicroscopy). In numerous cases, high-grade dysplasia ...

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    2. Interobserver Agreement for the Detection of Barrett’s Esophagus with Optical Frequency Domain Imagin

      Interobserver Agreement for the Detection of Barrett’s Esophagus with Optical Frequency Domain Imagin

      Background Optical frequency domain imaging (OFDI) is a second-generation form of optical coherence tomography (OCT) providing comprehensive cross-sectional views of the distal esophagus at a resolution of ~7 μm. Aim Using validated OCT criteria for squamous mucosa, gastric cardia mucosa, and Barrett’s esophagus (BE), the objective of this study was to determine the inter- and intra-observer agreements by a large number of OFDI readers for differentiating these tissues. Methods OFDI images were obtained from nine subjects undergoing screening and surveillance for BE. Sixty-four OFDI image regions of interest were randomly selected for review. A training set of 19 images ...

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    3. Dual-modality fluorescence and full-field optical coherence microscopy for biomedical imaging applications

      Dual-modality fluorescence and full-field optical coherence microscopy for biomedical imaging applications

      Full-field optical coherence microscopy (FFOCM) is a high-resolution interferometric technique that is particularly attractive for biomedical imaging. Here we show that combining it with structured illumination fluorescence microscopy on one platform can increase its versatility since it enables co-localized registration of optically sectioned reflectance and fluorescence images. To demonstrate the potential of this dual modality, a fixed and labeled mouse retina was imaged. Results showed that both techniques can provide complementary information and therefore the system could potentially be useful for biomedical imaging applications.

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    1-3 of 3
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    1. (2 articles) Harvard University
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    Dual-modality fluorescence and full-field optical coherence microscopy for biomedical imaging applications Interobserver Agreement for the Detection of Barrett’s Esophagus with Optical Frequency Domain Imagin Advanced precancerous lesions in the lower oesophageal mucosa: High-grade dysplasia and intramucosal carcinoma in Barrett's oesophagus Alterations of Hyaluronan Metabolism in Acute Coronary Syndrome: Implications for Plaque Erosion The vascular morphology of melanoma is related to Breslow index: an in vivo study with dynamic optical coherence tomography Optical Coherence Tomography in Glaucoma (Textbook) Aberration-diverse optical coherence tomography for suppression of multiple scattering and speckle Schlemm's canal measured by optical coherence tomography and correlation study in a healthy Caucasian child population Optical coherence tomography angiography and microvascular changes in diabetic retinopathy: a systematic review High-accuracy endoscopic microscopy using a thin, 1.5 mm diameter probe with optical coherence tomography A prospective case-control study comparing optical coherence tomography characteristics in neuromyelitis optica spectrum disorder- optic neuritis and idiopathic optic neuritis Ultra-wide optical coherence tomography angiography in diabetic retinopathy