1. Articles from Bernd Hamann

    1-9 of 9
    1. An iterative closest point approach for the registration of volumetric human retina image data obtained by optical coherence tomography

      An iterative closest point approach for the registration of volumetric human retina image data obtained by optical coherence tomography

      This paper introduces an improved approach for the volume data registration of human retina. Volume data registration refers to calculating out a near-optimal transformation between two volumes with overlapping region and stitching them together. Iterative closest point (ICP) algorithm is a registration method that deals with registration between points. Classical ICP is time consuming and often traps in local minimum when the overlapping region is not big enough. Optical Coherence Tomography (OCT) volume data are several separate, partially overlapping tiles. To stitch them together is a technology in computer aided diagnosis. In this paper, a new 3D registration algorithm based ...

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    2. Feature Of The Week 02/01/2015: Progress on Developing Adaptive Optics OCT for In Vivo Retinal Imaging: Monitoring and Correction of Eye Motion Artifacts (with Audio Narration)

      Feature Of The Week 02/01/2015: Progress on Developing Adaptive Optics OCT for In Vivo Retinal Imaging: Monitoring and Correction of Eye Motion Artifacts (with Audio Narration)

      Recent progress in retinal image acquisition techniques, including optical coherence tomography (OCT) and scanning laser ophthalmoscopy (SLO), combined with improved performance of adaptive optics (AO) instrumentation, has resulted in improvement in the quality of in vivo images of cellular structures in the human retina. Here, we present a short review of progress on developing AO-OCT instruments. Despite significant progress in imaging speed and resolution, eye movements present during acquisition of a retinal image with OCT introduce motion artifacts into the image, complicating analysis and registration. This effect is especially pronounced in high-resolution datasets acquired with AO-OCT instruments. Several retinal tracking ...

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    3. Progress on Developing Adaptive Optics-Optical Coherence Tomography for In Vivo Retinal Imaging: Monitoring and Correction of Eye Motion Artifacts

      Progress on Developing Adaptive Optics-Optical Coherence Tomography for In Vivo Retinal Imaging: Monitoring and Correction of Eye Motion Artifacts

      Recent progress in retinal image acquisition techniques, including optical coherence tomography (OCT) and scanning laser ophthalmoscopy (SLO), combined with improved performance of adaptive optics (AO) instrumentation, has resulted in improvement in the quality of in vivo images of cellular structures in the human retina. Here, we present a short review of progress on developing AO-OCT instruments. Despite significant progress in imaging speed and resolution, eye movements present during acquisition of a retinal image with OCT introduce motion artifacts into the image , complicating analysis and registration. This effect is especially pronounced in high-resolution datasets acquired with AO-OCT instruments. Several retinal tracking ...

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    4. Progress on Developing Adaptive Optics–Optical Coherence Tomography for In Vivo Retinal Imaging: Monitoring and Correction of Eye Motion Artifacts

      Progress on Developing Adaptive Optics–Optical Coherence Tomography for In Vivo Retinal Imaging: Monitoring and Correction of Eye Motion Artifacts

      Recent progress in retinal image acquisition techniques, including optical coherence tomography (OCT) and scanning laser ophthalmoscopy (SLO), combined with improved performance of adaptive optics (AO) instrumentation, has resulted in improvement in the quality of in vivo images of cellular structures in the human retina. Here, we present a short review of progress on developing AO-OCT instruments. Despite significant progress in imaging speed and resolution, eye movements present during acquisition of a retinal image with OCT introduce motion artifacts into the image, complicating analysis and registration. This effect is especially pronounced in high-resolution datasets acquired with AO-OCT instruments. Several retinal tracking ...

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    5. In-vivo imaging of inner retinal cellular morphology with adaptive optics-optical coherence tomography: challenges and possible solutions

      In-vivo imaging of inner retinal cellular morphology with adaptive optics-optical coherence tomography: challenges and possible solutions

      Recent progress in retinal image acquisition techniques, including optical coherence tomography (OCT) and scanning laser ophthalmoscopy (SLO), combined with improved performance of adaptive optics (AO) instrumentation, has resulted in improvement in the quality of in vivo images of cellular structures in the outer layers of the human retina. Despite the significant progress in imaging cone and rod photoreceptor mosaics, visualization of cellular structures in the inner retina has been achieved only with extrinsic contrast agents that have not been approved for use with humans. In this paper we describe the main limiting factors in visualizing inner retinal cells and the ...

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    6. Interactive processing and visualization of image data for biomedical and life science applications

      Interactive processing and visualization of image data for biomedical and life science applications
      Abstract Background  Applications in biomedical science and life science produce large data sets using increasingly powerful imaging devices and computer simulations. It is becoming increasingly difficult for scientists to explore and analyze these data using traditional tools. Interactive data processing and visualization tools can support scientists to overcome these limitations. Results  We show that new data processing tools and visualization systems can be used successfully in biomedical and life science applications. We present an adaptive high-resolution display system suitable for biomedical image data, algorithms for analyzing and visualization protein surfaces and retinal optical coherence tomography data, and visualization tools for ...
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    7. Cellular resolution volumetric in vivo retinal imaging with adaptive optics–optical coherence tomography

      Cellular resolution volumetric in vivo retinal imaging with adaptive optics–optical coherence tomography
      Ultrahigh-resolution adaptive optics–optical coherence tomography (UHR-AO-OCT) instrumentation allowing monochromatic and chromatic aberration correction was used for volumetric in vivo retinal imaging of various retinal structures including the macula and optic nerve head (ONH). Novel ... [Opt. Express 17, 4084-4094 (2009)]
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    8. Comparison of real-time visualization of volumetric OCT data sets by CPU-slicing and GPU-ray casting methods

      We describe and compare two volume visualization methods for Optical Coherence Tomography (OCT) retinal data sets. One of these methods is CPU-slicing, which is previously reported and used in our visualization engine. The other is GPU-ray casting. Several metrics including image quality, performanc ... [Proc. SPIE 7163, 716312 (2009)] published Wed Feb 18, 2009.
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    9. Improved representation of retinal data acquired with volumetric FD-OCT: co-registration, visualization and reconstruction of a large field of view

      Advances in Fourier-domain optical coherence tomography (Fd-OCT) permit visualization of three-dimensional morphology of in-vivo retinal structures in a way that promises to revolutionize clinical and experimental imaging of the retina. The relevance of these advances will be further increased by th ...
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    1-9 of 9
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  2. Topics in the News

    1. (9 articles) Bernd Hamann
    2. (8 articles) UC Davis
    3. (7 articles) John S. Werner
    4. (7 articles) Robert J. Zawadzki
    5. (5 articles) Arlie G. Capps
    6. (4 articles) Dae Yu Kim
    7. (3 articles) Alfred R. Fuller
    8. (2 articles) Lawrence Livermore National Laboratory
    9. (2 articles) Columbia University
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    12. (1 articles) UCSF
    13. (1 articles) Stanford University
    14. (1 articles) LuEsther T. Mertz Retinal Research Center
    15. (1 articles) UC Irvine
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    Cellular resolution volumetric in vivo retinal imaging with adaptive optics–optical coherence tomography Interactive processing and visualization of image data for biomedical and life science applications In-vivo imaging of inner retinal cellular morphology with adaptive optics-optical coherence tomography: challenges and possible solutions Progress on Developing Adaptive Optics–Optical Coherence Tomography for In Vivo Retinal Imaging: Monitoring and Correction of Eye Motion Artifacts Progress on Developing Adaptive Optics-Optical Coherence Tomography for In Vivo Retinal Imaging: Monitoring and Correction of Eye Motion Artifacts Feature Of The Week 02/01/2015: Progress on Developing Adaptive Optics OCT for In Vivo Retinal Imaging: Monitoring and Correction of Eye Motion Artifacts (with Audio Narration) An iterative closest point approach for the registration of volumetric human retina image data obtained by optical coherence tomography Lessons Learned From Avastin and OCT–The Great, the Good, the Bad, and the Ugly Investigation of longitudinal spatial coherence for electromagnetic optical fields Use of Vibrational Optical Coherence Tomography to Characterize Skin Lesions and a Congenital Nevus Varicella Retinal Vasculopathy: Unilateral Cilioretinal Artery Occlusion Despite Acyclovir Therapy Caught Using Optical Coherence Tomography-Angiography (OCTA) Assessment of tear meniscus by optical coherence tomography in patients with canalicular laceration repair