1. Articles from P. Albrecht

    1-2 of 2
    1. Quality control for retinal OCT in multiple sclerosis: validation of the OSCAR-IB criteria

      Quality control for retinal OCT in multiple sclerosis: validation of the OSCAR-IB criteria

      Background: Retinal optical coherence tomography (OCT) permits quantification of retinal layer atrophy relevant to assessment of neurodegeneration in multiple sclerosis (MS). Measurement artefacts may limit the use of OCT to MS research. Objective: An expert task force convened with the aim to provide guidance on the use of validated quality control (QC) criteria for the use of OCT in MS research and clinical trials. Methods: A prospective multi-centre ( n = 13) study. Peripapillary ring scan QC rating of an OCT training set ( n = 50) was followed by a test set ( n = 50). Inter-rater agreement was calculated using kappa statistics. Results were ...

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    2. Degeneration of retinal layers in multiple sclerosis subtypes quantified by optical coherence tomography

      Degeneration of retinal layers in multiple sclerosis subtypes quantified by optical coherence tomography

      Background: Optical coherence tomography can be used to assess retinal degeneration in multiple sclerosis (MS). Thinning of the retinal nerve fibre layer and macular thickness have been well characterized, but newer devices allow quantification of all retinal layers. Objectives: The objective of this study was to evaluate the thickness of the paramacular retina, peripapillary retinal nerve fibre layer, and deeper paramacular layers in MS patient subgroups, using state-of-the-art optical coherence tomography. Methods: Using a Heidelberg Engineering Spectralis device, we performed paramacular volumetric retinal scans and circular peripapillary fibre-layer scans, manually segmenting different retinal layers into single horizontal foveal scans in ...

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    1-2 of 2
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  2. Topics in the News

    1. (2 articles) Heinrich-Heine University Düsseldorf
    2. (1 articles) Johns Hopkins University
    3. (1 articles) Alexander Klistorner
    4. (1 articles) Fiona E. Costello
    5. (1 articles) Laura J. Balcer
    6. (1 articles) Axel Petzold
    7. (1 articles) Peter A. Calabresi
    8. (1 articles) Friedemann Paul
    9. (1 articles) Heidelberg Engineering
    10. (1 articles) Heidelberg Spectralis
    11. (1 articles) Harvard University
    12. (1 articles) Massachusetts General Hospital
    13. (1 articles) Delft University of Technology
    14. (1 articles) Chinese Academy of Sciences
    15. (1 articles) Robert A. Huber
    16. (1 articles) Gijs van Soest
    17. (1 articles) Jiefeng Xi
    18. (1 articles) Brett E. Bouma
    19. (1 articles) Anton F. W. van der Steen
    20. (1 articles) Notal Vision
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