1. Articles from Han T. Aung

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    1. Nasolabial Fold Angle Measurement Using Anterior Segment Optical Coherence Tomography in Normal Subjects

      Purpose: The human nasolabial fold angle (NFA) has been measured using MRI and photogrammetry and has been shown to decrease with age. The authors aimed to evaluate a novel method using optical coherence tomography to measure the NFA. Methods: In this cross-sectional observational series, the authors used anterior segment optical coherence tomography (ASOCT) to image the NFA of both cheeks of 126 subjects aged 21 to 79 years. A dental vinylpolysiloxane custom-designed mould was used as a chin rest. The mean of 3 scans on each side was calculated and analysis of variance, multiple comparisons, and multiple linear regression were ...
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    2. Comparison of Slitlamp Optical Coherence Tomography and Scanning Peripheral Anterior Chamber Depth Analyzer to Evaluate Angle Closure in Asian Eyes

      Objective To evaluate the effectiveness of slitlamp optical coherence tomography (SL-OCT) and Scanning Peripheral Anterior Chamber depth analyzer (SPAC) in detecting angle closure, using gonioscopy as the reference standard. Methods A total of 153 subjects underwent gonioscopy, SL-OCT, and SPAC. The anterior chamber angle (ACA) was classified as closed on gonioscopy if the posterior trabecular meshwork could not be seen; with SL-OCT, closure was determined by contact between the iris and angle wall anterior to the scleral spur; and with SPAC by a numerical grade of 5 or fewer and/or a categorical grade of suspect or potential. Results A ...
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    3. High-Definition Optical Coherence Tomography Imaging of the Iridocorneal Angle of the Eye

      Objective To assess the ability of high-definition optical coherence tomography (HD-OCT) to image the anterior chamber angle. Methods Forty-five consecutive subjects with phakic eyes underwent gonioscopy and anterior chamber angle imaging with HD-OCT adapted with a 60-diopter aspheric lens mounted over the imaging aperture. The patients' fixation was directed to the side using an external fixation light, and scans were taken of the temporal and nasal quadrants. The visibility of angle structures was assessed and the diagnosis of angle closure using HD-OCT was compared with that of gonioscopy. Results The majority of subjects were Chinese (91.1%) and female (62 ...
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    4. Variation of Angle Parameters in Asians: An Anterior Segment Optical Coherence Tomography Study in a Population of Singapore Malays

      Objective: To assess variations in angle parameters using anterior segment optical coherence tomography (AS-OCT) and to investigate demographic, ocular and systemic associations of angle width. Methods: This was a sub-study of a population based, cross-sectional survey of 3,280 (78.7% response rate) Malay people aged 40-80 years in Singapore. All participants underwent a standardized interview and ocular and systemic examination. AS-OCT was performed on 291 consecutive patients under standardized dark conditions. Angle opening distance (AOD-500) and trabecular-iris space area (TISA-500) 500 um from the scleral spur were determined for the nasal and temporal angles. Anterior chamber depth (ACD) was ...

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    5. Screening for Narrow Angles in the Singapore Population: Evaluation of New Noncontact Screening Methods

      Purpose: To assess the screening effectiveness of 3 new noncontact devices, the scanning peripheral anterior chamber depth analyzer (SPAC) (Takagi, Nagano, Japan), which measures peripheral anterior chamber depth (ACD); IOLMaster (Carl Zeiss Meditec, Jena, Germany), which measures central ACD; and Visante anterior segment optical coherence tomography (AS-OCT) (Visante, Carl Zeiss Meditec, Dublin, CA), which images the angles, and to compare these instruments with gonioscopy in identifying people with narrow angles (NAs).Design: Cross-sectional, observational, community-based study.Participants: Phakic subjects aged ≥50 years without ophthalmic symptoms who were recruited from a community polyclinic in Singapore.Methods: All subjects underwent examination with ...

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    6. Assessment of the Scleral Spur in Anterior Segment Optical Coherence Tomography Images

      Objective  To assess visibility of the scleral spur in anterior segment optical coherence tomography (AS-OCT) images. Methods  This cross-sectional observational study included 502 participants aged 50 years or older who had no previous ophthalmic problems and were recruited from a community clinic in Singapore. All participants underwent gonioscopy and AS-OCT (Visante; Carl Zeiss Meditec, Dublin, California). Scleral spur location was assessed in AS-OCT images by 2 examiners with glaucoma subspecialty training and was defined as the point where there was an inward protrusion of the sclera with a change in curvature of its inner surface. Results  Scleral spur location could ...

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    7. Corneal Imaging with Anterior Segment Optical Coherence Tomography for Lamellar Keratoplasty Procedures

      Ten eyes of eight patients with pathologies involving the corneal stroma and sparing the Descemet membrane (DM) were included in this study conducted at a tertiary care hospital. The indications for DALK included corneal clouding attributable to mucopolysaccharidoses (n = 2), macular corneal dystrophy (n = 5), lattice corneal dystrophy (n = 1), granular corneal dystrophy (n = 1), and stromal scar attributable to infectious keratitis (n = 1). DALK was performed using the big-bubble technique in o
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    1-7 of 7
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    1. (7 articles) Singapore Eye Research Institute
    2. (7 articles) National University of Singapore
    3. (3 articles) Johns Hopkins University
    4. (3 articles) Carl Zeiss Meditec
    5. (2 articles) Boston University
    6. (2 articles) Massachusetts General Hospital
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