1. Articles from Sharon D. Solomon

    1-3 of 3
    1. Retinal layer parcellation of optical coherence tomography images: Data resource for Multiple Sclerosis and Healthy Controls

      Retinal layer parcellation of optical coherence tomography images: Data resource for Multiple Sclerosis and Healthy Controls

      This paper presents optical coherence tomography (OCT) images of the human retina and manual delineations of eight retinal layers. The data includes 35 human retina scans acquired on a Spectralis OCT system (Heidelberg Engineering, Heidelberg, Germany), 14 of which are healthy controls (HC) and 21 have a diagnosis of multiple sclerosis (MS). The provided data includes manually delineation of eight retina layers, which were independently reviewed and edited. The data presented in this article was used to validate automatic segmentation algorithms [1].

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    2. Combined registration and motion correction of longitudinal retinal OCT data

      Combined registration and motion correction of longitudinal retinal OCT data

      Optical coherence tomography (OCT) has become an important modality for examination of the eye. To measure layer thicknesses in the retina, automated segmentation algorithms are often used, producing accurate and reliable measurements. However, subtle changes over time are difficult to detect since the magnitude of the change can be very small. Thus, tracking disease progression over short periods of time is difficult. Additionally, unstable eye position and motion alter the consistency of these measurements, even in healthy eyes. Thus, both registration and motion correction are important for processing longitudinal data of a specific patient. In this work, we propose a ...

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    3. Detection of New-Onset Choroidal Neovascularization Using Optical Coherence Tomography: The Amd Doc Study

      Detection of New-Onset Choroidal Neovascularization Using Optical Coherence Tomography: The Amd Doc Study

      Purpose To determine the sensitivity of time domain optical coherence tomography (OCT) in detecting conversion to neovascular age-related macular degeneration (AMD) in eyes at high risk for choroidal neovascularization (CNV), compared with detection using fluorescein angiography (FA) as the gold standard. Design Prospective, multicenter, observational study. Participants Individuals aged ≥50 years with nonneovascular AMD at high risk of progressing to CNV in the study eye and evidence of neovascular AMD in the fellow eye. Methods At study entry and every 3 months through 2 years, participants underwent best-corrected visual acuity, supervised Amsler grid testing, preferential hyperacuity perimetry (PHP) testing, stereoscopic ...

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    1-3 of 3
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    Detection of New-Onset Choroidal Neovascularization Using Optical Coherence Tomography: The Amd Doc Study Combined registration and motion correction of longitudinal retinal OCT data Retinal layer parcellation of optical coherence tomography images: Data resource for Multiple Sclerosis and Healthy Controls Vascular Response of Orsiro vs. Xience Drug-Eluting Stents for Treating Coronary Bifurcation Lesions Trojan-Horse Diameter-Reducible Nanotheranostics for Macroscopic/Microscopic Imaging-Monitored Chemo-Antiangiogenic Therapy Prediction of Neoplastic Progression in Barrett’s Esophagus Using Nanoscale Nuclear Architecture Mapping: A Pilot Study Thickness of retinal pigment epithelium–Bruch’s membrane complex in adult Chinese using optical coherence tomography Interocular symmetry of optical coherence tomography parameters in healthy children and adolescents Fluorescein Leakage and Optical Coherence Tomography Angiography Features of Microaneurysms in Diabetic Retinopathy Cross-free in both lateral and axial directions Fourier-domain full-field optical coherence tomography Microperimetry, Humphrey field analyzer, and optical coherence tomography in detecting glaucoma: a comparative performance study Scanning optimization of an electrothermally-actuated MEMS mirror for applications in optical coherence tomography endoscopy