1. Articles from Anthony Kuo

    1-11 of 11
    1. Systems and methods for arbitrary viewpoint robotic manipulation and robotic surgical assistance

      Systems and methods for arbitrary viewpoint robotic manipulation and robotic surgical assistance

      Systems and methods for arbitrary viewpoint robotic manipulation and robotic surgical assistance are disclosed. According to an aspect, a system includes one or more controllers configured to receive an image dataset of an actual environment within which the robotic tool is positioned. The controller(s) are also configured to generate a virtual environment of the actual environment based on the image dataset. Further, the controller(s) can control display of the virtual environment including a virtual tool controllable by a user for use to control the robotic tool within the actual environment. The controller(s) can receive user input for ...

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    2. Prevalence, risk factors and impact of posterior staphyloma diagnosed from wide‐field optical coherence tomography in Singapore adults with high myopia

      Prevalence, risk factors and impact of posterior staphyloma diagnosed from wide‐field optical coherence tomography in Singapore adults with high myopia

      Purpose To investigate the prevalence and risk factors of posterior staphyloma using wide‐field optical coherence tomography (WF‐OCT) in adults with high myopia in Singapore. Design Population‐based cross‐sectional study. Methods Adults with spherical equivalent (SE) ≤ −5D in either eye at the first visit of Singapore Epidemiology of Eye Diseases study and Singapore Prospective Study Program study were recruited. Posterior staphyloma was diagnosed using WF‐OCT (PLEX ® Elite9000, Carl Zeiss Meditec). Myopic macular degeneration (MMD), myopic traction maculopathy (MTM) and vision‐related quality of life (VRQoL) were assessed using fundus photographs, DRI‐Triton OCT (Topcon) and the Impact ...

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    3. Whole eye optical coherence tomography (OCT) imaging systems and related methods

      Whole eye optical coherence tomography (OCT) imaging systems and related methods

      Whole eye optical coherence tomography (OCT) imaging systems and related methods are disclosed. According to an aspect, an OCT imaging system includes a source having an associated source arm path. Further, the OCT imaging system includes a reference arm coupled to the source arm. Further, the OCT imaging system includes a sample arm having an associated sample arm path and coupled to the source arm. The sample arm includes at least one optical component configured to simultaneously scan both an anterior and posterior portion of an eye of a subject.

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    4. Toward Autonomous Robotic Micro-Suturing using Optical Coherence Tomography Calibration and Path Planning

      Toward Autonomous Robotic Micro-Suturing using Optical Coherence Tomography Calibration and Path Planning

      Robotic automation has the potential to assist human surgeons in performing suturing tasks in microsurgery, and in order to do so a robot must be able to guide a needle with sub-millimeter precision through soft tissue. This paper presents a robotic suturing system that uses 3D optical coherence tomography (OCT) system for imaging feedback. Calibration of the robot-OCT and robot-needle transforms, wound detection, keypoint identification, and path planning are all performed automatically. The calibration method handles pose uncertainty when the needle is grasped using a variant of iterative closest points. The path planner uses the identified wound shape to calculate ...

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    5. Optical Coherence Tomography Guided Robotic Needle Insertion for Deep Anterior Lamellar Keratoplasty

      Optical Coherence Tomography Guided Robotic Needle Insertion for Deep Anterior Lamellar Keratoplasty

      Objective: Deep anterior lamellar keratoplasty (DALK) significantly reduces the post-transplantation morbidity in patients eligible for partial-thickness cornea grafts. The popular "big bubble" technique for DALK is so challenging, however, that a significant fraction of corneal pneumodissection attempts fail for surgeons without extensive DALK-specific experience, even with previous-generation cross-sectional optical coherence tomography (OCT) guidance. We seek to develop robotic, volumetric OCT-guided technology capable of facilitating or automating the difficult needle insertion step in DALK. Methods: Our system provides for real-time volumetric corneal imaging, segmentation, and tracking of the needle insertion to display feedback for surgeons and to generate needle insertion plans ...

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    6. Feature of the Week 06/24/2018: Duke University Researchers Show Exciting Advances in Live OCT Volumes in Immersive Virtual Reality

      Feature of the Week 06/24/2018: Duke University Researchers Show Exciting Advances in Live OCT Volumes in Immersive Virtual Reality

      Virtual reality (VR) head-mounted displays are an attractive technology for viewing intrasurgical optical coherence tomography (OCT) volumes because they liberate surgeons from microscope oculars. We demonstrate real-time, interactive viewing of OCT volumes in a commercial HTC Vive immersive VR system using previously reported ray casting techniques. Furthermore, we show interactive manipulation and sectioning of volumes using handheld controllers and guidance of mock surgical procedures in porcine eyes exclusively within VR. To the best of our knowledge, we report the first immersive VR-OCT viewer with stereo ray casting volumetric renders, arbitrary sectioning planes, and live acquisition support. We believe VR-OCT volume ...

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    7. Real-time visualization and interaction with static and live optical coherence tomography volumes in immersive virtual reality

      Real-time visualization and interaction with static and live optical coherence tomography volumes in immersive virtual reality

      Virtual reality (VR) head-mounted displays are an attractive technology for viewing intrasurgical optical coherence tomography (OCT) volumes because they liberate surgeons from microscope oculars. We demonstrate real-time, interactive viewing of OCT volumes in a commercial HTC Vive immersive VR system using previously reported ray casting techniques. Furthermore, we show interactive manipulation and sectioning of volumes using handheld controllers and guidance of mock surgical procedures in porcine eyes exclusively within VR. To the best of our knowledge, we report the first immersive VR-OCT viewer with stereo ray casting volumetric renders, arbitrary sectioning planes, and live acquisition support. We believe VR-OCT volume ...

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    8. 4D microscope-integrated OCT improves accuracy of ophthalmic surgical maneuvers

      4D microscope-integrated OCT improves accuracy of ophthalmic surgical maneuvers

      Ophthalmic surgeons manipulate micron-scale tissues using stereopsis through an operating microscope and instrument shadowing for depth perception. While ophthalmic microsurgery has benefitted from rapid advances in instrumentation and techniques, the basic principles of the stereo operating microscope have not changed since the 1930’s. Optical Coherence Tomography (OCT) has revolutionized ophthalmic imaging and is now the gold standard for preoperative and postoperative evaluation of most retinal and many corneal procedures. We and others have developed initial microscope-integrated OCT (MIOCT) systems for concurrent OCT and operating microscope imaging, but these are limited to 2D real-time imaging and require offline post-processing for ...

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    9. Novel microscope-integrated stereoscopic display for intrasurgical optical coherence tomography

      Novel microscope-integrated stereoscopic display for intrasurgical optical coherence tomography

      The first generation of intrasurgical optical coherence tomography (OCT) systems displayed OCT data onto a separate computer monitor, requiring surgeons to look away from the surgical microscope. In order to provide real-time OCT feedback without requiring surgeons to look away during surgeries, recent prototype research and commercial intrasurgical OCT systems have integrated heads-up display (HUD) systems into the surgical microscopes to allow the surgeons to access the OCT data and the surgical field through the oculars concurrently. However, all current intrasurgical OCT systems with a HUD are only capable of imaging through one ocular limiting the surgeon’s depth perception ...

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    10. Simultaneous swept source optical coherence tomography of the anterior segment and retina using coherence revival

      Simultaneous swept source optical coherence tomography of the anterior segment and retina using coherence revival

      We report on an implementation of coherence revival-based heterodyne swept source optical coherence tomography that is capable of simultaneously imaging the anterior and posterior eye. A polarization-encoded sample arm was used to efficiently focus orthogonal polarizations on the anterior segment and retina. Depth encoding was achieved using coherence revival, which allows for multiple depths within a sample to be simultaneously imaged and frequency encoded by carefully controlling the optical pathlength of each sample path. This design is a significant step toward whole-eye optical coherence tomography (OCT), which would enable customized ray-traced modeling of patient eyes to improve refractive surgical interventions ...

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    11. Dual-depth SSOCT for simultaneous complex resolved anterior segment and conventional retinal imaging

      Dual-depth SSOCT for simultaneous complex resolved anterior segment and conventional retinal imaging

      We present a novel optical coherence tomography (OCT) system design that employs coherence revival-based heterodyning and polarization encoding to simultaneously image the ocular anterior segment and the retina. Coherence revival heterodyning allows for multiple depths within a sample to be simultaneously imaged and frequency encoded by carefully controlling the optical pathlength of each sample path. A polarization-encoded sample arm was used to direct orthogonal polarizations to the anterior segment and retina. This design is a significant step toward realizing whole-eye OCT, which would enable customized ray-traced modeling of patient eyes to improve refractive surgical interventions, as well as the elimination ...

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    1-11 of 11
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  2. Topics in the News

    1. (11 articles) Duke University
    2. (11 articles) Anthony N. Kuo
    3. (10 articles) Joseph A. Izatt
    4. (4 articles) Oscar Carrasco-Zevallos
    5. (4 articles) Mark Draelos
    6. (3 articles) University of Washington
    7. (2 articles) Al-Hafeez Dhalla
    8. (2 articles) Cynthia A. Toth
    9. (2 articles) Ruikang K. Wang
    10. (1 articles) Columbia University
    11. (1 articles) Paul V. Hahn
    12. (1 articles) Topcon Medical Systems
    13. (1 articles) Zhejiang University
    14. (1 articles) Cleveland Clinic
    15. (1 articles) UCSD
    16. (1 articles) Sunil K. Srivastava
    17. (1 articles) Justis P. Ehlers
    18. (1 articles) William R. Freeman
    19. (1 articles) Peng Li
    20. (1 articles) Optovue
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    Dual-depth SSOCT for simultaneous complex resolved anterior segment and conventional retinal imaging Simultaneous swept source optical coherence tomography of the anterior segment and retina using coherence revival Novel microscope-integrated stereoscopic display for intrasurgical optical coherence tomography 4D microscope-integrated OCT improves accuracy of ophthalmic surgical maneuvers Real-time visualization and interaction with static and live optical coherence tomography volumes in immersive virtual reality Feature of the Week 06/24/2018: Duke University Researchers Show Exciting Advances in Live OCT Volumes in Immersive Virtual Reality Optical Coherence Tomography Guided Robotic Needle Insertion for Deep Anterior Lamellar Keratoplasty Toward Autonomous Robotic Micro-Suturing using Optical Coherence Tomography Calibration and Path Planning Whole eye optical coherence tomography (OCT) imaging systems and related methods Prevalence, risk factors and impact of posterior staphyloma diagnosed from wide‐field optical coherence tomography in Singapore adults with high myopia Impact of cardiometabolic factors on retinal vasculature: A 3x3, 6x6 and 8x8-mm optical coherence tomography angiography study Quantitative research on the interaction between cerebral edema and peripheral cerebral blood perfusion using swept-source optical coherence tomography