1. Articles from Anh Nguyen-Huynh

    1-3 of 3
    1. Feature Of The Week 6/17/12: Middle Ear Vibrometry of Human Cadaver Temporal Bone with Spectral Domain Phase-Sensitive Optical Coherence Tomography

      Feature Of The Week 6/17/12: Middle Ear Vibrometry of Human Cadaver Temporal Bone with Spectral Domain Phase-Sensitive Optical Coherence Tomography

      Hearing loss is the most frequent sensory deficit in the human population, affecting more than 250 million people in the world. The National Center for Health Statistics estimates that 37 million adults (17%) in the United States have hearing difficulty. Analysis of a large database of audiometric records from the University of Minnesota reveals that 39% of patients diagnosed with hearing loss have conductive hearing loss (CHL) either alone (15%) or in combination with SNHL (24%). There are several contemporary audiological tests that are commonly used to diagnose middle ear function for CHL. However, these contemporary tests of middle ear ...

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    2. Feasibility of spectral-domain phase-sensitive optical coherence tomography for middle ear vibrometry

      Feasibility of spectral-domain phase-sensitive optical coherence tomography for middle ear vibrometry

      We describe a novel application of spectral-domain phase-sensitive optical coherence tomography (SD PS-OCT) to detect the tiny motions of the middle ear structures, such as the tympanic membrane and ossicular chain, and their morphological features for differential diagnosis of CHL. This technique has the potential to provide meaningful vibration of ossicles with a vibration sensitivity of ∼ 0.5  nm at 1 kHz of acoustic stimulation. To the best of our knowledge, this is the first demonstration of depth-resolved vibration imaging of ossicles with a PS-OCT system at a nanometer scale.

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    3. Simultaneous depth-resolved imaging of sub-nanometer scale ossicular vibrations and morphological features of the human-cadaver middle ear with spectral-domain phase-sensitive optical coherence tomography

      Simultaneous depth-resolved imaging of sub-nanometer scale ossicular vibrations and morphological features of the human-cadaver middle ear with spectral-domain phase-sensitive optical coherence tomography

      We describe a novel method for the detection of the tiny motions of the middle ear (ME) ossicles and their morphological features with a spectral-domain phase sensitive optical coherence tomography (PS-OCT). Laser Doppler Vibrometry (LDV) and its variations are the most extensively used methods for studding the vibrational modes of the ME. However, most techniques are limited to single point analysis methods, and do not have the ability to provide depth resolved simultaneous imaging of multiple points on the ossicles especially with the intact eardrum. Consequently, the methods have the limited ability to provide relative vibration information at these points ...

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    1-3 of 3
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  2. Topics in the News

    1. (3 articles) Oregon Health & Science University
    2. (3 articles) University of Washington
    3. (3 articles) Ruikang K. Wang
    4. (3 articles) Anh T. Nguyen-Huynh
    5. (3 articles) Alfred L. Nuttall
    6. (3 articles) Hrebesh M. Subhash
    7. (2 articles) Steven L. Jacques
    8. (1 articles) University of Minnesota
    9. (1 articles) British Columbia Cancer Agency
    10. (1 articles) Shanghai Jiao Tong University
    11. (1 articles) Singapore Eye Research Institute
    12. (1 articles) Simon Fraser University
    13. (1 articles) Columbia University
    14. (1 articles) Stephen Lam
    15. (1 articles) Pierre M. Lane
    16. (1 articles) Tien Yin Wong
    17. (1 articles) Giuseppe Querques
    18. (1 articles) Francesco Bandello
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