1. Articles from Leodante da Costa

    1-7 of 7
    1. Endovascular optical coherence tomography imaging in cerebrovascular disease

      Endovascular optical coherence tomography imaging in cerebrovascular disease

      Endovascular optical coherence tomography (OCT) is the highest resolution imaging modality currently available with spatial resolution of 10 µm. Although originally developed for interventional cardiology, the ability to visualize the luminal environment and anatomy, along with the stent-vessel interaction could be of great utility for various cerebrovascular diseases, and the adoption of endovascular OCT imaging in the evolving field of interventional neuroradiology seems instinctive. The purpose of this study is to conduct a systematic review of the literature regarding applications of endovascular OCT in the diagnosis and treatment of cerebrovascular diseases. In addition, the authors report their institutional experience with ...

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    2. Optical coherence tomography imaging after endovascular thrombectomy: a novel method for evaluating vascular injury in a swine model

      Optical coherence tomography imaging after endovascular thrombectomy: a novel method for evaluating vascular injury in a swine model

      Although studies have shown that some degree of iatrogenic endothelial injury occurs during endovascular thrombectomy (EVT), the clinical significance of such injury is uncertain. Furthermore, it is likely that iatrogenic effects such as endothelial denudation, intimal dissection, and tunica media edema will have varying clinical implications. The purpose of this study was to assess the feasibility of endovascular optical coherence tomography (OCT) in quantifying vessel injury in real time after EVT, correlate vessel injury with histological findings, and perform imaging at varying time intervals after EVT to assess the impact of prolonged direct exposure of the vessel to the thrombus ...

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    3. Optical coherence tomography–guided flow diversion for aneurysmal treatment

      Optical coherence tomography–guided flow diversion for aneurysmal treatment

      A 28-year-old man presenting with right third nerve palsy was diagnosed with a giant unruptured aneurysm supplied by the right posterior communicating and cerebral arteries (figure 1, A and B). The aneurysm was treated with flow-diverting stent-assisted coiling. Two months later, he presented with new-onset left-sided weakness, and MRI showed increased edema in the thalamus (figure 1C) and increased aneurysm size and no filling. There was no evidence of stent malapposition with high-resolution cone-beam (VASO) CT (figure 2). Angiography and optical coherence tomography (OCT) imaging demonstrated no stent endothelialization over a patent portion of the aneurysm neck (figure 3). 1 ...

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    4. Optical coherence tomography imaging after endovascular thrombectomy for basilar artery occlusion: report of 3 cases

      Optical coherence tomography imaging after endovascular thrombectomy for basilar artery occlusion: report of 3 cases

      Studies evaluating individuals for endothelial injury after endovascular thrombectomy (EVT) have been done by means of retrieved human thrombus, MR vessel-wall imaging, and animal histopathological studies. These techniques have limitations, because MR imaging has insufficient spatial resolution to directly visualize endothelium, and histopathological examinations are performed ex vivo and are unable to provide real-time patterns of injury. The purpose of the current study was to obtain in vivo intraluminal imaging after EVT by using optical coherence tomography (OCT), examining for evidence of endothelial injury in real time. Three consecutive patients with acute basilar artery occlusion underwent OCT imaging immediately after ...

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    5. Optical Coherence Tomography as an Adjunct During Carotid Artery Stenting for Carotid Atherosclerotic Disease

      Optical Coherence Tomography as an Adjunct During Carotid Artery Stenting for Carotid Atherosclerotic Disease

      Purpose Carotid artery stenting (CAS) has been proven to decrease the risk of stroke in symptomatic patients with moderate/high-grade carotid stenosis; however, there is an increased periprocedural risk of stroke with CAS compared to carotid endarterectomy. The goal of this article is to report the utilization of endovascular optical coherence tomography (OCT) during CAS to aid in the identification of stent malapposition, plaque prolapse, and adjacent residual thrombus that could cause periprocedural stroke. Methods Approval was obtained for endovascular OCT imaging in patients undergoing CAS. Images were obtained before and after stenting. Images were acquired with proximal balloon occlusion ...

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    6. Feasibility and methodology of optical coherence tomography imaging of human intracranial aneurysms: ex vivo pilot study

      Feasibility and methodology of optical coherence tomography imaging of human intracranial aneurysms: ex vivo pilot study

      Rupture of intracranial aneurysm is a common cause of subarachnoid hemorrhage. An aneurysm may undergo microscopic morphological changes or remodeling of the vessel wall prior to rupture, which could potentially be imaged. In this study we present methods of tissue sample preparation of intracranial aneurysms and correlation between optical coherence tomography imaging and routine histology. OCT has a potential future in the assessment of microscopic features of aneurysms, which may correlate to the risk of rupture.

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    1-7 of 7
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    Feasibility and methodology of optical coherence tomography imaging of human intracranial aneurysms: ex vivo pilot study Optical Coherence Tomography as an Adjunct During Carotid Artery Stenting for Carotid Atherosclerotic Disease Optical coherence tomography imaging after endovascular thrombectomy for basilar artery occlusion: report of 3 cases Optical coherence tomography–guided flow diversion for aneurysmal treatment Optical coherence tomography as an adjunct during carotid artery stenting for carotid web Optical coherence tomography imaging after endovascular thrombectomy: a novel method for evaluating vascular injury in a swine model Endovascular optical coherence tomography imaging in cerebrovascular disease Optical Coherence Tomography: Critical Tool to Manage Expectations after Cataract Extraction Improving the characterization of ex vivo human brain optical properties using high numerical aperture optical coherence tomography by spatially constraining the confocal parameters Choroidal, macular and ganglion cell layer thickness assessment in Caucasian children measured with spectral domain optical coherence tomography Examination of retinal vascular density changes via optical coherence tomography angiography in patients with glaucoma 3D reconstruction of coronary artery bifurcations from coronary angiography and optical coherence tomography: feasibility, validation, and reproducibility