All Articles from Leodante da Costa -Optical Coherence Tomography News

Articles from Leodante da Costa

1-8 of 8
1. Minimally invasive intrathecal spinal cord imaging with optical coherence tomography
  
  Explore SPIE Digital Library May 17 2021
  
  ignificance: Imaging of the spinal cord is challenging due to the surrounding bony anatomy, physiologic motion, and the small diameter of the spinal cord. This precludes the use of non-invasive imaging techniques in assessing structural changes related to trauma and evaluating residual function. Aim: The purpose of our research was to apply endovascular technology and techniques and construct a preclinical animal model of intrathecal spinal cord imaging using optical coherence tomography (OCT). Approach: Five animals (2 Yorkshire Swine and 3 New Zealand Rabbits) were utilized. Intrathecal access was gained using a 16-guage Tuohy, and an OCT catheter was advanced under ...
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  Mentions: University of Toronto Sunnybrook Health Sciences Centre
2. Endovascular optical coherence tomography imaging in cerebrovascular disease
  
  Explore ScienceDirect Aug 24 2020 Cardiology , Neurology
  
  Endovascular optical coherence tomography (OCT) is the highest resolution imaging modality currently available with spatial resolution of 10 µm. Although originally developed for interventional cardiology, the ability to visualize the luminal environment and anatomy, along with the stent-vessel interaction could be of great utility for various cerebrovascular diseases, and the adoption of endovascular OCT imaging in the evolving field of interventional neuroradiology seems instinctive. The purpose of this study is to conduct a systematic review of the literature regarding applications of endovascular OCT in the diagnosis and treatment of cerebrovascular diseases. In addition, the authors report their institutional experience with ...
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  Mentions: University of Toronto Sunnybrook Health Sciences Centre
3. Optical coherence tomography imaging after endovascular thrombectomy: a novel method for evaluating vascular injury in a swine model
  
  Explore thejns.org Feb 18 2020 Cardiology , Neurology
  
  Although studies have shown that some degree of iatrogenic endothelial injury occurs during endovascular thrombectomy (EVT), the clinical significance of such injury is uncertain. Furthermore, it is likely that iatrogenic effects such as endothelial denudation, intimal dissection, and tunica media edema will have varying clinical implications. The purpose of this study was to assess the feasibility of endovascular optical coherence tomography (OCT) in quantifying vessel injury in real time after EVT, correlate vessel injury with histological findings, and perform imaging at varying time intervals after EVT to assess the impact of prolonged direct exposure of the vessel to the thrombus ...
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4. Optical coherence tomography as an adjunct during carotid artery stenting for carotid web
  
  Explore Neurology Feb 12 2020 Cardiology , Neurology
  
  Consider optical coherence tomography as an adjunct to visualize the membrane of a carotid web, the extent of the web, and aid in placement of a carotid stent.
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  Mentions: University of Toronto Sunnybrook Health Sciences Centre Ryerson University
5. Optical coherence tomography–guided flow diversion for aneurysmal treatment
  
  Explore Neurology Sep 22 2019 Cardiology , Neurology
  
  A 28-year-old man presenting with right third nerve palsy was diagnosed with a giant unruptured aneurysm supplied by the right posterior communicating and cerebral arteries (figure 1, A and B). The aneurysm was treated with flow-diverting stent-assisted coiling. Two months later, he presented with new-onset left-sided weakness, and MRI showed increased edema in the thalamus (figure 1C) and increased aneurysm size and no filling. There was no evidence of stent malapposition with high-resolution cone-beam (VASO) CT (figure 2). Angiography and optical coherence tomography (OCT) imaging demonstrated no stent endothelialization over a patent portion of the aneurysm neck (figure 3). 1 ...
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  Mentions: University of Toronto Sunnybrook Health Sciences Centre Ryerson University
6. Optical coherence tomography imaging after endovascular thrombectomy for basilar artery occlusion: report of 3 cases
  
  Explore thejns.org Aug 27 2019 Cardiology , Neurology
  
  Studies evaluating individuals for endothelial injury after endovascular thrombectomy (EVT) have been done by means of retrieved human thrombus, MR vessel-wall imaging, and animal histopathological studies. These techniques have limitations, because MR imaging has insufficient spatial resolution to directly visualize endothelium, and histopathological examinations are performed ex vivo and are unable to provide real-time patterns of injury. The purpose of the current study was to obtain in vivo intraluminal imaging after EVT by using optical coherence tomography (OCT), examining for evidence of endothelial injury in real time. Three consecutive patients with acute basilar artery occlusion underwent OCT imaging immediately after ...
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  Mentions: University of Toronto Sunnybrook Health Sciences Centre
7. Optical Coherence Tomography as an Adjunct During Carotid Artery Stenting for Carotid Atherosclerotic Disease
  
  Explore Home - Springer Jun 4 2019 Cardiology
  
  Purpose Carotid artery stenting (CAS) has been proven to decrease the risk of stroke in symptomatic patients with moderate/high-grade carotid stenosis; however, there is an increased periprocedural risk of stroke with CAS compared to carotid endarterectomy. The goal of this article is to report the utilization of endovascular optical coherence tomography (OCT) during CAS to aid in the identification of stent malapposition, plaque prolapse, and adjacent residual thrombus that could cause periprocedural stroke. Methods Approval was obtained for endovascular OCT imaging in patients undergoing CAS. Images were obtained before and after stenting. Images were acquired with proximal balloon occlusion ...
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  Mentions: University of Toronto Sunnybrook Health Sciences Centre
8. Feasibility and methodology of optical coherence tomography imaging of human intracranial aneurysms: ex vivo pilot study
  
  Explore SPIE Digital Library Feb 17 2012
  
  Rupture of intracranial aneurysm is a common cause of subarachnoid hemorrhage. An aneurysm may undergo microscopic morphological changes or remodeling of the vessel wall prior to rupture, which could potentially be imaged. In this study we present methods of tissue sample preparation of intracranial aneurysms and correlation between optical coherence tomography imaging and routine histology. OCT has a potential future in the assessment of microscopic features of aneurysms, which may correlate to the risk of rupture.
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  Mentions: Massachusetts General Hospital Harvard University Sunnybrook Health Sciences Centre
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