1. Articles from Patrick Raphael

    1-2 of 2
    1. ELHnet: a convolutional neural network for classifying cochlear endolymphatic hydrops imaged with optical coherence tomography

      ELHnet: a convolutional neural network for classifying cochlear endolymphatic hydrops imaged with optical coherence tomography

      Detection of endolymphatic hydrops is important for diagnosing Meniere’s disease, and can be performed non-invasively using optical coherence tomography (OCT) in animal models as well as potentially in the clinic. Here, we developed ELHnet, a convolutional neural network to classify endolymphatic hydrops in a mouse model using learned features from OCT images of mice cochleae. We trained ELHnet on 2159 training and validation images from 17 mice, using only the image pixels and observer-determined labels of endolymphatic hydrops as the inputs. We tested ELHnet on 37 images from 37 mice that were previously not used, and found that the ...

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    2. Methodology for assessment of structural vibrations by spectral domain optical coherence tomography

      Methodology for assessment of structural vibrations by spectral domain optical coherence tomography

      Clinical diagnosis of cochlear dysfunction typically remains incomplete due to a lack of proper diagnostic methods. Medical imaging modalities can only detect gross changes in the cochlea, and non-invasive in vivo cochlear measurements are scarce. As a result, extensive efforts have been made to adapt optical coherence tomography (OCT) techniques to analyze and study the cochlea. Herein, we detail the methods for measuring vibration using OCT. We used spectral domain OCT with ~950 nm as the center wavelength and a bandwidth of ~80 nm. The custom spectrometer used was based on a high speed line scan camera which is capable ...

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      Mentions: Rice University
    1-2 of 2
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  2. Topics in the News

    1. (1 articles) University of Southern California
    2. (1 articles) Stanford University
    3. (1 articles) Rice University
    4. (1 articles) Texas A&M University
    5. (1 articles) San Raffaele Scientfic Institute
    6. (1 articles) Carl Zeiss Meditec
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