1. Articles from Chen Lu

    1-6 of 6
    1. Changes in the Macular Vascular Density After Bariatric Surgery Measured by Optical Coherence Tomography Angiograph

      Changes in the Macular Vascular Density After Bariatric Surgery Measured by Optical Coherence Tomography Angiograph

      Objective : The objective is to study the diagnosis of coronary heart disease by optical coherence tomography based on random walk algorithm, so as to assist doctors in diagnosing coronary heart disease. Method : K -means algorithm combined with mathematical morphology provides seed points for random walk algorithm, and realizes semi-automatic segmentation of different kinds of patches. Secondly, by adding the space distance term based on the distance between the edge and the seed point in the weight function, the random walk algorithm is improved, which can make the weak edge patch area not be segmented too much. Results : the results were ...

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    2. Diagnosis of Coronary Heart Disease by Optical Coherence Tomography Using Random Walk Algorithm

      Diagnosis of Coronary Heart Disease by Optical Coherence Tomography Using Random Walk Algorithm

      Objective : The objective is to study the diagnosis of coronary heart disease by optical coherence tomography based on random walk algorithm, so as to assist doctors in diagnosing coronary heart disease. Method : K -means algorithm combined with mathematical morphology provides seed points for random walk algorithm, and realizes semi-automatic segmentation of different kinds of patches. Secondly, by adding the space distance term based on the distance between the edge and the seed point in the weight function, the random walk algorithm is improved, which can make the weak edge patch area not be segmented too much. Results : the results were ...

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    3. Cardiac-Gated En Face Doppler Measurement of Retinal Blood Flow Using Swept Source Optical Coherence Tomography at 100,000 Axial Scans per Second

      Cardiac-Gated En Face Doppler Measurement of Retinal Blood Flow Using Swept Source Optical Coherence Tomography at 100,000 Axial Scans per Second

      Purpose: To develop and demonstrate a cardiac gating method for repeatable in vivo measurement of total retinal blood flow (TRBF) in humans using en face Doppler optical coherence tomography (OCT) at commercially available imaging speeds. Methods: A prototype swept-source OCT system operating at 100 kHz axial scan rate was developed and interfaced with a pulse oximeter. Using the plethysmogram measured from the earlobe, Doppler OCT imaging of a 1.5 mm×2 mm area at the optic disc at 1.8 volumes/sec was synchronized to cardiac cycle to improve sampling of pulsatile blood flow. Post-processing algorithms were developed to ...

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    4. In-Vivo Lamina Cribrosa Microarchitecture in Healthy and Glaucomatous Eyes as Assessed by Optical Coherence Tomography

      In-Vivo Lamina Cribrosa Microarchitecture in Healthy and Glaucomatous Eyes as Assessed by Optical Coherence Tomography

      Purpose: Lamina cribrosa (LC) is a leading location of glaucomatous damage. The purpose of this study is to compare LC 3-dimensional microarchitecture between healthy and glaucomatous eyes in-vivo using optical coherence tomography (OCT). Methods: Sixty-eight eyes (19 healthy and 49 glaucomatous) from 47 subjects were scanned in a 3.5x3.5x3.64mm volume (400x400x896 pixels) at the optic nerve head using swept-source OCT. The LC microarchitecture parameters were measured on the visible LC by an automated segmentation algorithm. The LC parameters were compared to diagnosis and visual field mean deviation (MD) using a linear mixed effects model accounting for age ...

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    5. Imaging limbal and scleral vasculature using Swept Source Optical Coherence Tomography

      Imaging limbal and scleral vasculature using Swept Source Optical Coherence Tomography

      We demonstrate application of high-speed swept source optical coherence tomography for vessel visualization in the anterior segment of the human eye. The human corneo-scleral junction and sclera was imaged in vivo. Imaging was performed using a swept source OCT system operating at 1050nm wavelength range and 100kHz A-scan rate. The high imaging speed enables generation of 3D depth-resolved vasculature maps. The vessel visualization method revealed the rich vascular system in the conjunctiva and episclera. Full Text: PDF References: D. Huang et al., "Optical coherence tomography", Science 254, 1178 (1991). [CrossRef] W. Drexler, J. G. Fujimoto (ed.), Optical Coherence Tomography. Technology ...

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    1-6 of 6
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  2. Topics in the News

    1. (4 articles) Massachusetts Institute of Technology
    2. (2 articles) University of Pittsburgh
    3. (1 articles) Tufts University
    4. (1 articles) Center for Ophthalmic Optics and Lasers
    5. (1 articles) University of Erlangen
    6. (1 articles) Oregon Health & Science University
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    Imaging limbal and scleral vasculature using Swept Source Optical Coherence Tomography In-Vivo Lamina Cribrosa Microarchitecture in Healthy and Glaucomatous Eyes as Assessed by Optical Coherence Tomography Cardiac-Gated En Face Doppler Measurement of Retinal Blood Flow Using Swept Source Optical Coherence Tomography at 100,000 Axial Scans per Second OCT vitrectomy probe Diagnosis of Coronary Heart Disease by Optical Coherence Tomography Using Random Walk Algorithm Changes in the Macular Vascular Density After Bariatric Surgery Measured by Optical Coherence Tomography Angiograph The truth about invisible posterior vitreous structures Increased Macrophage-like Cell Density in Retinal Vein Occlusion as Characterized by en Face Optical Coherence Tomography The Influence of Eyelid Position and Environmental Conditions on the Corneal Changes in Early Postmortem Interval: A Prospective, Multicentric OCT Study The Use of Optical Coherence Tomography for Gross Examination and Sampling of Fixed Breast Specimens: A Pilot Study The Role of Widefield and Ultra Widefield Optical Coherence Tomography in the Diagnosis and Management of Vitreoretinal Diseases Acute Idiopathic Blind Spot Enlargement Syndrome-New Perspectives in the OCT Era