1. Articles from Utkarsh Sharma

    1-24 of 35 1 2 »
    1. Methods and apparatus for reducing artifacts in OCT angiography using machine learning techniques

      Methods and apparatus for reducing artifacts in OCT angiography using machine learning techniques

      In some embodiments of the present invention, a method of reducing artifacts includes obtaining OCT/OCTA data from an OCT/OCTA imager; preprocessing OCTA/OCT volume data; extracting features from the preprocessed OCTA/OCT volume data; classifying the OCTA/OCT volume data to provide a probability determination data; determining a percentage data from the probability data determination; and reducing artifacts in response to the percentage data.

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    2. Opening for Technology Director – Core Products at Volk Optical Inc.

      Opening for Technology Director – Core Products at Volk Optical Inc.

      Position Summary The Technology Director role presents an exciting opportunity to lead and mentor a highly talented, dynamic and motivated team of engineers working on sustaining, enhancing and developing of currently marketed and new core products including diagnostic, laser and surgical lenses, surgical systems and marketed diagnostic imaging devices. The Product Development team at Volk embraces a culture of collaborative teamwork, impactful & customer-centric innovation, free exchange of ideas, fast-paced development, entrepreneurial mindset and can-do attitude. The ideal candidate will be a hands-on leader with a strong technical background and track record of developing new medical device products. The Director will ...

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      Mentions: Utkarsh Sharma
    3. Optical Design Engineering Opening at Volk Optical

      Optical Design Engineering Opening at Volk Optical

      About us: Volk Optical, Inc. (Mentor, OH) is the leading design, development and manufacturing company for ophthalmic lenses and portable imaging devices. The company’s products include portable diagnostic ophthalmic imaging systems (Volk iNview and Pictor Plus), as well as a full line of reusable and single-use diagnostic, laser and surgical lenses. The Product Development team at Volk is a group of motivated and dynamic team-players who embrace a culture of openness, free exchange of ideas, fast-paced development, entrepreneurial mindset and can-do attitude. We are passionate about developing new ideas, products and solutions to fulfill Volk’s purpose of eradicating ...

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      Mentions: Utkarsh Sharma
    4. Staff Optical Systems Scientist at Optovue

      Staff Optical Systems Scientist at Optovue

      About us: Optovue, Inc. (Fremont, CA) is an ophthalmic device company dedicated to working with eye care professionals, doctors and researchers to improve patient care through sustained technological innovation. The Advanced Development Team at Optovue is primarily responsible for identifying, evaluating and developing cutting-edge technologies in the field of ophthalmic and optical imaging. Innovation is firmly entrenched in our DNA and we take pride in the fact that Optovue has pioneered disruptive medical imaging technologies including spectral-domain OCT and OCT Angiography that have been revolutionizing the field of ophthalmology. We remain passionate about generating, prototyping and evaluating new concepts and ...

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    5. Methods of reducing motion artifacts for optical coherence tomography angiography

      Methods of reducing motion artifacts for optical coherence tomography angiography

      A method for reducing motion artifacts in optical coherence tomography (OCT) angiography images is disclosed. The method is applied to the intensity or complex OCT data prior to applying the motion contrast analysis and involves determining sub-pixel level shifts between at least two B-scans repeated approximately at the same location and applying the sub-pixel level shifts to the B-scans to be able to correct for motion and accurately determine motion contrast signal. A preferred embodiment includes the use of 2D cross correlations to register a series of B-scans in both the axial (z-) and lateral (x-) dimensions and a convolution ...

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    6. Acquistion and analysis techniques for improved outcomes in optical coherence tomography angiography

      Acquistion and analysis techniques for improved outcomes in optical coherence tomography angiography
      Abstract

      Methods for improved acquisition and processing of optical coherence tomography (OCT) angiography data are presented. One embodiment involves improving the acquisition of the data by evaluating the quality of different portions of the data to identify sections having non-uniform acquisition parameters or non-uniformities due to opacities in the eye such as floaters. The identified sections can then be brought to the attention of the user or automatically reacquired. In another embodiment, segmentation of layers in the retina includes both structural and flow information derived from motion contrast processing. In a further embodiment, the health of the eye is evaluating ...

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    7. Mechanical Design Engineer Opening at Optovue

      Mechanical Design Engineer Opening at Optovue

      Scope: TheMechanical Engineer role provides an opportunity to work with a highly cross-functional group of scientists and engineers to contribute towards next generation products in the field of ophthalmic imaging. The candidate will lead mechanical and opto-mechanical aspects of the sub-systems design in new product development as well as sustaining engineering projects. Strong verbal and written communications skills are essential, and you must be able to multitask and work effectively at all levels in a fluid environment. Interested candidates please contact: sarika_gulhar@optovue.com and/or renata_bartula@optovue.com. Responsibilities: Design of machines, mechanism, machined, sheet-metal, die casting and injection ...

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    8. Evaluation of artifact reduction in optical coherence tomography angiography with real-time tracking and motion correction technology

      Evaluation of artifact reduction in optical coherence tomography angiography with real-time tracking and motion correction technology

      Artifacts introduced by eye motion in optical coherence tomography angiography (OCTA) affect the interpretation of images and the quantification of parameters with clinical value. Eradication of such artifacts in OCTA remains a technical challenge. We developed an algorithm that recognizes five different types of motion artifacts and used it to evaluate the performance of three motion removal technologies. On en face maximum projection of flow images, the summed flow signal in each row and column and the correlation between neighboring rows and columns were calculated. Bright line artifacts were recognized by large summed flow signal. Drifts, distorted lines, and stretch ...

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    9. Analysis and visualization of OCT angiography data

      Analysis and visualization of OCT angiography data

      Methods for analyzing and visualizing OCT angiography data are presented. In one embodiment, an automated method for identifying the foveal avascular zone in a two dimensional en face image generated from motion contrast data is presented. Several 3D visualization techniques are presented including one in which a particular vessel is selected in a motion contrast image and all connected vessels are highlighted. A further embodiment includes a stereoscopic visualization method. In addition, a variety of metrics for characterizing OCT angiography image data are described.

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    10. Wide-field optical coherence tomography based microangiography for retinal imaging

      Wide-field optical coherence tomography based microangiography for retinal imaging

      Optical coherence tomography angiography (OCTA) allows for the evaluation of functional retinal vascular networks without a need for contrast dyes. For sophisticated monitoring and diagnosis of retinal diseases, OCTA capable of providing wide-field and high definition images of retinal vasculature in a single image is desirable. We report OCTA with motion tracking through an auxiliary real-time line scan ophthalmoscope that is clinically feasible to image functional retinal vasculature in patients, with a coverage of more than 60 degrees of retina while still maintaining high definition and resolution. We demonstrate six illustrative cases with unprecedented details of vascular involvement in retinal ...

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    11. Split integration mode acquisition for optimized OCT imaging at multiple speeds

      Split integration mode acquisition for optimized OCT imaging at multiple speeds

      Split Integration Mode (SIM) acquisition schemes are presented that enable optical coherence tomography (OCT) imaging at multiple rates. SIM enables a system and method of operation having a first mode and a second mode, wherein the fundamental acquisition rate of the detector is the same in the two modes, but wherein the generated signals in the second mode are digitally combined prior to signal processing to create a data set with an effective acquisition rate less than the fundamental acquisition rate.

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    12. Systems and methods for improved acquisition of ophthalmic optical coherence tomography data

      Systems and methods for improved acquisition of ophthalmic optical coherence tomography data

      Systems and methods for improved acquisition of ophthalmic optical coherence tomography data are presented, allowing for enhanced ease of use and higher quality data and analysis functionality. Embodiments include automated triggering for detecting and initiating collection of OCT ophthalmic data, an automated technique for determining the optimal number of B-scans to be collected to create the highest quality image and optimize speckle reduction, automated review of fundus images collected with an adjunct imaging modality to guide the OCT data collection, a single scan protocol in which a large field of view is collected with HD B-scans embedded at different locations ...

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    13. Systems and methods for faster optical coherence tomography acquisition and processing

      Systems and methods for faster optical coherence tomography acquisition and processing

      Systems and methods for faster acquisition and processing of OCT image data are presented. In one embodiment of the present invention, an OCT system is operated in two different acquisition modes of different axial resolutions to allow for efficient collection of OCT Angiography data while also collecting high resolution OCT data. In another embodiment, a reduced subset of a collected data set is used for OCT Angiography data analysis. In another embodiment, a sweep of a swept-source laser is split into different spectral components covering different transverse locations on the sample. A further aspect includes the ability to process all ...

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    14. SWEPT SOURCE OCT ANGIOGRAPHY OF NEOVASCULAR MACULAR TELANGIECTASIA TYPE 2

      SWEPT SOURCE OCT ANGIOGRAPHY OF NEOVASCULAR MACULAR TELANGIECTASIA TYPE 2

      Background/Purpose: To image subretinal neovascularization in proliferative macular telangiectasia Type 2 (MacTel2) using swept source optical coherence tomography based microangiography (OMAG). Methods: Patients with macular telangiectasia Type 2 were enrolled in a prospective, observational study known as the MacTel Project and evaluated using a high-speed 1,050 nm swept-source OCT prototype system. The OMAG algorithm generated en face flow images from three retinal layers, and the region bounded by the outer retina and Bruch membrane, the choriocapillaris, and the remaining choroidal vasculature. The en face OMAG images were compared with images from fluorescein angiography and indocyanine green angiography. Results ...

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    15. Systems and methods for enhanced accuracy in OCT imaging of the cornea

      Systems and methods for enhanced accuracy in OCT imaging of the cornea

      Systems and methods for enhanced accuracy in optical coherence tomography imaging of the cornea are presented, including approaches for more accurate corneal surface modeling, pachymetry maps, keratometric values, and corneal power. These methods involve new scan patterns, an eye tracking mechanism for transverse motion feedback, and advanced motion correction algorithms. In one embodiment the methods comprise acquiring a first sparse set of data, using that data to create a corneal surface model, and then using the model to register a second set of denser data acquisition. This second set of data is used to create a more accurate, motion-corrected model ...

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    16. Segmentation and enhanced visualization techniques for full-range fourier domain optical coherence tomography

      Segmentation and enhanced visualization techniques for full-range fourier domain optical coherence tomography

      Presented here are new processing techniques for optical coherence tomography (OCT) data that allow for improved visualization and use of full-range OCT images. These techniques minimize the central line artifact and the complex conjugate artifact without requiring additional system hardware or significantly increasing post-processing time. The central line artifact is minimized by normalizing each A-scan to account for ripples at the zero-delay position. The complex conjugate artifact is minimized by segmentation of a layer or layers that cross the zero-delay position, and in some embodiments by further segmentation of other surfaces based on the segmentation of the initial layer or ...

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    17. Wide-field imaging of retinal vasculature using optical coherence tomography-based microangiography provided by motion tracking.

      Wide-field imaging of retinal vasculature using optical coherence tomography-based microangiography provided by motion tracking.

      Optical coherence tomography (OCT)-based optical microangiography (OMAG) is a high-resolution, noninvasive imaging technique capable of providing three-dimensional in vivo blood flow visualization within microcirculatory tissue beds in the eye. Although the technique has demonstrated early clinical utility by imaging diseased eyes, its limited field of view (FOV) and the sensitivity to eye motion remain the two biggest challenges for the widespread clinical use of the technology. Here, we report the results of retinal OMAG imaging obtained from a Zeiss Cirrus 5000 spectral domain OCT system with motion tracking capability achieved by a line scan ophthalmoscope (LSO). The tracking LSO ...

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    18. Swept-Source OCT Angiography of Macular Telangiectasia Type 2

      Swept-Source OCT Angiography of Macular Telangiectasia Type 2

      BACKGROUND AND OBJECTIVE: To evaluate the central macular microvascular network in patients with macular telangiectasia type 2 (MacTel2) using optical coherence tomography (OCT)-based microangiography (OMAG). PATIENTS AND METHODS: Prospective, observational study of patients with MacTel2 evaluated using a swept-source OCT (SS-OCT) prototype. OMAG was performed using a 3 mm × 3 mm central foveal raster scan. The algorithm segmented the retina into three layers. Microvascular distribution was depicted as en face images, and qualitative information was compared to fluorescein angiography (FA) images. RESULTS: OMAG detected abnormal microvasculature in all MacTel2 eyes, predominantly in the middle retinal layers with neovascularization in ...

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    19. Swept-Source OCT Angiography of the Retinal Vasculature Using Intensity Differentiation-based Optical Microangiography Algorithms

      Swept-Source OCT Angiography of the Retinal Vasculature Using Intensity Differentiation-based Optical Microangiography Algorithms

      To demonstrate the feasibility of using a 1,050-nm swept-source optical coherence tomography (SS-OCT) system to achieve noninvasive retinal vasculature imaging in human eyes. MATERIALS AND METHODS: Volumetric data sets were acquired using a 1-µm SS-OCT prototype that operated at a 100-kHz A-line rate. A scanning protocol designed to allow for motion contrast processing, referred to as OCT angiography or optical microangiography (OMAG), was used to scan an approximately 3 × 3–mm area in the central macular region of the retina within approximately 4.5 seconds. An intensity differentiation-based OMAG algorithm was used to extract three-dimensional retinal functional microvasculature ...

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    20. Segmentation And Enhanced Visualization Techniques For FULL-RANGE Fourier Domain Optical Coherence Tomography

      Segmentation And Enhanced Visualization Techniques For FULL-RANGE Fourier Domain Optical Coherence Tomography

      Presented here are new processing techniques for optical coherence tomography (OCT) data that allow for improved visualization and use of full-range OCT images. These techniques minimize the central line artifact and the complex conjugate artifact without requiring additional system hardware or significantly increasing post-processing time. The central line artifact is minimized by normalizing each A-scan to account for ripples at the zero-delay position.

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    21. Data Acquisition Methods For Reduced Motion Artifacts And Applications In Oct Angiography

      Data Acquisition Methods For Reduced Motion Artifacts And Applications In Oct Angiography

      Systems and methods for reducing the effects of motion on functional optical coherence tomography (OCT) imaging are described. Embodiments including post-processing and motion tracking are presented. A preferred embodiment in which functional OCT data is collected and analyzed for motion as a multiple scan unit is described. An extension of the invention to the collection of large field of view or montaged functional OCT data sets is also presented.

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    22. Systems And Methods For Enhanced Accuracy In OCT Imaging Of The Cornea

      Systems And Methods For Enhanced Accuracy In OCT Imaging Of The Cornea

      Systems and methods for enhanced accuracy in optical coherence tomography imaging of the cornea are presented, including approaches for more accurate corneal surface modeling, pachymetry maps, keratometric values, and corneal power. These methods involve new scan patterns, an eye tracking mechanism for transverse motion feedback, and advanced motion correction algorithms. In one embodiment the methods comprise acquiring a first sparse set of data, using that data to create a corneal surface model, and then using the model to register a second set of denser data acquisition. This second set of data is used to create a more accurate, motion-corrected model ...

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    23. Systems And Methods For SWEPT-SOURCE Optical Coherence Tomography

      Systems And Methods For SWEPT-SOURCE Optical Coherence Tomography

      Systems and methods for increasing the duty cycle and/or producing interleaved pulses of alternating polarization states in swept-source optical coherence tomography (OCT) systems are considered. Embodiments including improved buffering, frequency selecting filter sharing among multiple SOAs, intracavity switching, and multiple wavelength bands are described. The unique polarization properties of the source configurations have advantages in speckle reduction, polarization-sensitive measurements, polarization state dependent phase shifts, spatial shifts, and temporal shifts in OCT measurements.

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    24. Improved Data Acquisition Methods For Reduced Motion Artifacts And Applications In Oct Angiography

      Improved Data Acquisition Methods For Reduced Motion Artifacts And Applications In Oct Angiography

      Systems and methods for reducing the effects of motion on functional optical coherence tomography (OCT) imaging are described. Embodiments including post-processing and motion tracking are presented.A preferred embodiment in which functional OCT data is collected and analyzed for motion as a multiple scan unit is described. An extension of the invention to the collection of large field of view or montaged functional OCT data sets is also presented.

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    1-24 of 35 1 2 »
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    1. (35 articles) Utkarsh Sharma
    2. (19 articles) Carl Zeiss Meditec
    3. (6 articles) University of Illinois at Urbana-Champaign
    4. (6 articles) University of Washington
    5. (6 articles) Ruikang K. Wang
    6. (6 articles) Lin An
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