1. Articles from Yuko Yamada

    1-14 of 14
    1. The Ability of SD-OCT to Differentiate Early Glaucoma With High Myopia From Highly Myopic Controls and Nonhighly Myopic Controls

      The Ability of SD-OCT to Differentiate Early Glaucoma With High Myopia From Highly Myopic Controls and Nonhighly Myopic Controls

      Purpose : Optical coherence tomography (OCT) instruments do not embed a normative database from highly myopic normal (HMN) eyes. The abilities of three OCT instruments to detect early glaucoma with high myopia were compared using the two controls with or without high myopia. Methods : A total of 52 early glaucomatous eyes (mean deviation > −6.0 dB) with high myopia (spherical equivalent ≤ −6.0 diopters [HMG]), 54 HMN eyes, and 90 nonhighly myopic normal (NHMN) eyes were enrolled. Each participant was imaged using Cirrus, RTVue, and Topcon 3D OCT to evaluate the thicknesses of the circumpapillary retinal nerve fiber layer (cpRNFL), the ...

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    2. Difference in correspondence between visual field defect and inner macular layer thickness measured using three types of spectral-domain OCT instruments

      Difference in correspondence between visual field defect and inner macular layer thickness measured using three types of spectral-domain OCT instruments

      Purpose To compare the relationship between visual field sensitivity (VFS) and macular parameters measured using three spectral-domain optical coherence tomography (SD-OCT) instruments and to determine a base level (=floor effect) for macular parameters. Methods We imaged 127 glaucomatous eyes (1 eye per subject) using three different OCT instruments, i.e., the Cirrus , RTVue and 3D OCT devices; 76 normal eyes were evaluated as controls using the same instruments. The thicknesses of the macular retinal nerve fiber layer (mRNFL), ganglion cell layer+inner plexiform layer (GCL/IPL), and mRNFL+GCL/IPL (GCC) were analyzed. The VFS of the area analyzed by ...

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    3. The detection of macular analysis by SD-OCT for optic chiasmal compression neuropathy and nasotemporal overlap

      The detection of macular analysis by SD-OCT for optic chiasmal compression neuropathy and nasotemporal overlap

      Purposes: To assess the diagnostic performance of the macular parameters detected by spectral domain-optical coherence tomography (SD-OCT) in band atrophy (BA) eyes. Methods: Forty-nine BA eyes with permanent temporal hemianopia and 89 normal eyes were enrolled. Any patients who had nasal visual field loss were excluded. Each participant was imaged by 3D OCT-2000, and 10×10 grids in the macula were automatically allocated. The thickness of the macular retinal nerve fiber layer (mRNFL), ganglion cell layer (GCL)+ (GCL+inner plexiform layer (IPL)), and GCL++ thickness (RNFL+GCL+IPL) in both nasal and temporal hemiretina were calculated and compared between the ...

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    4. Cluster analyses of grid-pattern display in macular parameters using optical coherence tomography for glaucoma diagnosis

      Cluster analyses of grid-pattern display in macular parameters using optical coherence tomography for glaucoma diagnosis

      Purpose: Using spectral-domain optical coherence tomography (SD-OCT), we assessed the ability of cluster analyses based on the grid-pattern of macular parameters to detect glaucoma. Methods: Seventy-five normal eyes, 64 early glaucomatous eyes (EG) and 40 preperimetric glaucomatous eyes (PPG) were enrolled. Each participant was imaged using 3D OCT to examine the macular retinal nerve fiber layer (mRNFL) and the thickness of the ganglion cell layer together with the inner plexiform layer (GCL/IPL). Diagnostic criteria based on the clustering of abnormal grids from the mRNFL and GCL/IPL measurements were applied. The sensitivity and specificity of glaucoma detection were compared ...

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    5. The ability of macular parameters and circumpapillary retinal nerve fiber layer by three SD-OCT instruments to diagnose highly myopic glaucoma

      The ability of macular parameters and circumpapillary retinal nerve fiber layer by three SD-OCT instruments to diagnose highly myopic glaucoma

      Purpose: To compare the ability of circumpapillary retinal nerve fiber layer (cpRNFL) thickness and macular parameters obtained by three spectral-domain optical coherence tomography (SD-OCT) instruments to detect highly myopic glaucoma. Methods: In this study, 84 glaucomatous eyes, 53 normal eyes with high myopia and 86 normal eyes (not highly myopic) were enrolled. Each participant was imaged using Cirrus, RTVue and 3D OCT to evaluate the average and quadrant cpRNFL thicknesses. The macular retinal nerve fiber layer (mRNFL), ganglion cell layer + inner plexiform layer (GCL/IPL) and mRNFL+GCL/IPL (GCC) thicknesses were analyzed. The areas under the receiver operating characteristic ...

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    6. Comparative Assessment for the Ability of Cirrus, RTVue, and 3D-OCT to Diagnose Glaucoma

      Comparative Assessment for the Ability of Cirrus, RTVue, and 3D-OCT to Diagnose Glaucoma

      Purpose. We compared the ability of circumpapillary retinal nerve fiber layer (cpRNFL) thickness and macular parameters obtained by three spectral-domain optical coherence tomography (SD-OCT) instruments to detect glaucoma. Methods. We enrolled 87 normal eyes and 145 glaucomatous eyes (75 early glaucomatous eyes (EGs), mean deviation > −6 dB). Each participant was imaged using Cirrus, RTVue, and 3D-OCT to evaluate the average and quadrant cpRNFL thicknesses. The macular retinal nerve fiber layer (mRNFL), ganglion cell layer plus inner plexiform layer (GCL/IPL), and mRNFL + GCL/IPL (ganglion cell complex [GCC]) thicknesses were analyzed. The areas under the receiver operating characteristic curves (AUCs ...

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    7. Structure–function relationship among three types of spectral-domain optical coherent tomography instruments in measuring parapapillary retinal nerve fibre layer thickness

      Structure–function relationship among three types of spectral-domain optical coherent tomography instruments in measuring parapapillary retinal nerve fibre layer thickness

      Purpose: To compare the relationships of parapapillary retinal nerve fibre layer (RNFL) thickness among three spectral-domain optical coherence tomography (SD-OCT) instruments with visual field sensitivity (VFS). Methods: One hundred and thirteen eyes of 113 Japanese subjects with glaucoma (mean deviation in standard automated perimetry = −8.9 ± 6.7 dB) were imaged by Cirrus, RTVue and 3D OCT. The average hemi-superior and hemi-inferior RNFL thicknesses were obtained. In addition, the structure–function relationship using two retinotopic maps that consisted of six or nine sectors was also evaluated. Decibel (dB) scale and 1/Lamert (1/L) were used to express VFS. RNFL ...

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    8. Longitudinal Study of Retinal Nerve Fiber Layer Thickness and Ganglion Cell Complex in Traumatic Optic Neuropathy

      Longitudinal Study of Retinal Nerve Fiber Layer Thickness and Ganglion Cell Complex in Traumatic Optic Neuropathy

      Optical coherence tomography (OCT) has been developed to objectively evaluate structural damage in vivo. The tool can be used to evaluate damage to the circumpapillary retinal nerve fiber layer (cpRNFL). Measurements of the cpRNFL play an important role in the diagnosis and management of patients with glaucoma. The recent introduction of spectral-domain OCT has enhanced the scan resolution and provides more reproducibility for image acquisition compared with time-domain OCT, a previous version of OCT. Furthermore, the RTVue (Optovue Inc), one of the spectral-domain OCT instruments, allows us to evaluate inner retinal layer thickness. Reference to the ganglion cell complex (GCC ...

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    9. Spectral-domain optical coherence tomography detects optic atrophy due to optic tract syndrome

      Spectral-domain optical coherence tomography detects optic atrophy due to optic tract syndrome

      Abstract Background  Unilateral injury of the optic tract leads to asymmetrical optic atrophy in both eyes derived from the crossing of the nerve fibers at the chiasm. This report demonstrates unique imaging appearances of optic atrophy due to this uncommon condition detected by spectral-domain optical coherence tomography (SD-OCT). Methods  Cirrus and RTVue measurements were performed in four cases of optic tract syndrome. Circumpapillary retinal nerve fiber layer (cpRNFL) thickness was obtained from both instruments and ganglion cell complex (GCC) integrity was obtained from RTVue. The presumable reduction rates of quadrant cpRNFL thickness were calculated from the published normative database and ...

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    10. Better performance of RTVue than Cirrus spectral-domain optical coherence tomography in detecting band atrophy of the optic nerve

      Better performance of RTVue than Cirrus spectral-domain optical coherence tomography in detecting band atrophy of the optic nerve

      Abstract Background  To assess the agreement and diagnostic performance between retinal nerve fiber layer (RNFL) thickness measurements obtained using the Cirrus (Carl Zeiss Meditec) and RTVue (Optovue Inc.) devices for detection of band atrophy (BA) in patients with permanent temporal hemianopia. Methods  In this retrospective study, 26 eyes with BA and 64 control eyes were enrolled. The Cirrus optic disc cube protocol and the RTVue optic nerve head map protocol were used. The Cirrus measurements were extracted and regrouped to be topographically matched with the RTVue measurements. Concordance correlation and 95 % limits of agreement were assessed. Areas under the receiver ...

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    11. Effects of ocular rotation on parapapillary retinal nerve fiber layer thickness analysis measured with spectral-domain optical coherence tomography

      Effects of ocular rotation on parapapillary retinal nerve fiber layer thickness analysis measured with spectral-domain optical coherence tomography

      Purpose To evaluate the effects of ocular rotation on parapapillary retinal nerve fiber layer (RNFL) thickness measured by spectral-domain optical coherence tomography (SD-OCT). Patients and methods Eighty-eight normal and 205 glaucomatous eyes were studied. RNFL thickness was measured by 3D OCT. Ocular rotation angle was measured from a fundus image obtained by a non-mydriatic fundus camera equipped with 3D OCT. The average, hemi-superior, and hemi-inferior RNFL thicknesses as well as those in the 4 quadrants and the 16-segmented superotemporal (ST-1) and inferotemporal (IT-4) sectors were compared both before and after correcting for ocular rotation. Receiver operating characteristic curves and the ...

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    12. Agreement among three types of spectral-domain optical coherent tomography instruments in measuring parapapillary retinal nerve fibre layer thickness

      Agreement among three types of spectral-domain optical coherent tomography instruments in measuring parapapillary retinal nerve fibre layer thickness

      Backgrounds/aims To evaluate the agreement of parapapillary retinal nerve fibre layer (RNFL) thickness among three spectral-domain optical coherence tomography (OCT) instruments. Methods Two hundred and three glaucomatous eyes and 88 normal eyes were imaged by Cirrus, RTVue and 3D OCT. The average and the four quadrant RNFL thicknesses were evaluated. Agreement among RNFL measurements was evaluated using Bland–Altman analysis and linear regression analysis. The percentage of each quadrant in the average RNFL thickness value was compared among the three instruments. Results Cirrus showed significantly smaller thickness values than RTVue (difference=8.8 μm, p<0.0001) and 3D OCT (difference=8.1 μm, p<0.0001). Although RNFL measurements among the instruments were highly correlated, the Bland–Altman analysis revealed proportional biases for most of the pair-wise agreements. Additionally, 3D OCT showed strong proportional biases with RTVue and 3D OCT. RTVue had a smaller occupied proportion of nasal quadrants (30.2%) and a larger proportion of inferior quadrants (32.4%) compared with Cirrus and 3D OCT. Conclusions RNFL measurements among the instruments were well correlated but had different values for thickness. The measurement circle of RTVue might be more superior-temporally located compared with the other instruments. Differences in the measurement protocols might be affected by the disagreements. These instruments should not be used interchangeably.

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    13. Serous Macular Detachment Due to Diabetic Papillopathy Detected Using Optical Coherence Tomography

      Diabetic papillopathy (DP) is a syndrome characterized by self-limited unilateral or bilateral optic disc swelling associated with minimal or no permanent loss of visual function.1-3 Diabetic papillopathy may occur in patients with type 1 diabetes mellitus (DM)1 and type 2 DM,2-3 with approximately a 0.5% incidence1 irrespective of metabolic control and severity of diabetic retinopathy. Reportedly, DP often (in approximately 70% of cases) accompanies macular edema, which is a major cause of vision loss in patients with DP even without retinal capillary leakage and is presumed to be an extension of disc edema in some cases ...
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    14. Regional Relationship Between Retinal Nerve Fiber Layer Thickness and Corresponding Visual Field Sensitivity in Glaucomatous Eyes

      Objective  To establish the structure-function relationship between peripapillary retinal nerve fiber layer (RNFL) thickness and visual field (VF) test points in standard automated perimetry. Methods  We included 213 eyes with open-angle glaucoma and VF loss in this cross-sectional study. Correlations between individual VF sensitivity at 52 test points and peripapillary RNFL thickness divided into 16 sectors were calculated. The RNFL thickness was measured by Stratus optical coherence tomography. A new VF cluster map corresponding to RNFL sectors was generated by grouping the VF test points with the highest relation to each RNFL sector. Results  The VF sensitivity at each test ...
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    1-14 of 14
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  2. Topics in the News

    1. (14 articles) Makoto Nakamura
    2. (14 articles) Akiyasu Kanamori
    3. (11 articles) Kobe University Graduate School of Medicine
    4. (9 articles) Optovue RTVue-100
    5. (8 articles) Optovue
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    Agreement among three types of spectral-domain optical coherent tomography instruments in measuring parapapillary retinal nerve fibre layer thickness Effects of ocular rotation on parapapillary retinal nerve fiber layer thickness analysis measured with spectral-domain optical coherence tomography Better performance of RTVue than Cirrus spectral-domain optical coherence tomography in detecting band atrophy of the optic nerve Spectral-domain optical coherence tomography detects optic atrophy due to optic tract syndrome Longitudinal Study of Retinal Nerve Fiber Layer Thickness and Ganglion Cell Complex in Traumatic Optic Neuropathy Structure–function relationship among three types of spectral-domain optical coherent tomography instruments in measuring parapapillary retinal nerve fibre layer thickness Comparative Assessment for the Ability of Cirrus, RTVue, and 3D-OCT to Diagnose Glaucoma The ability of macular parameters and circumpapillary retinal nerve fiber layer by three SD-OCT instruments to diagnose highly myopic glaucoma Optoretinography: optical measurements of human cone and rod photoreceptor responses to light Nodular skin lesions: correlation of reflectance confocal microscopy (RCM) and optical coherence tomography (OCT) features OCT and Ophthalmology in the Age of Artificial Intelligence, Tuesday Oct 8, 2019 1:00P EDT Compensation for the Influence of Fluctuations in the Distance to the Object During Noncontact Probing in Spectral Domain Optical Coherence Tomography