1. Articles from Mariko Ehara

    1-7 of 7
    1. Association of coronary plaque composition and arterial remodelling: A optical coherence tomography study - Corrected Proof

      Association of coronary plaque composition and arterial remodelling: A optical coherence tomography study - Corrected Proof

      Background Conflicting data have been reported about the association between plaque composition and remodelling index (RI). The aim of this study is to evaluate the relationship between plaque morphology obtained by optical coherence tomography (OCT) and arterial remodelling. Methods and results OCT and intravascular ultrasound imaging pull back was performed at corresponding sites on 94 lesions in 47 patients. OCT plaque characteristics for lipid content, fibrous cap thickness, thin-cap fibroatheroma (TCFA), plaque rupture, thrombus, calcification and erosion were derived using validated criteria. Compared with intermediate/negative remodelling (RI<1.0), positive remodelling (RI>1.0) was associated with presence of higher lipid pool (2.86 ...

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    2. The impact of epicardial fat volume on coronary plaque vulnerability: insight from optical coherence tomography analysis

      The impact of epicardial fat volume on coronary plaque vulnerability: insight from optical coherence tomography analysis

      Aims Epicardial fat volume (EFV) has been implicated in coronary artery disease. Relationship between EFV and coronary plaque vulnerability has not been elucidated. The aim of this study was to investigate the association of EFV with coronary plaque vulnerability by using optical coherence tomography (OCT). Methods and results We enrolled 117 patients who underwent multislice computed tomography (MSCT) and OCT. EFV was quantified on MSCT. Patients were categorized according to tertiles of EFV: low tertile, EFV 3 ; mid-tertile, 104.1 cm 3 ≤ EFV ≤ 130.7 cm 3 ; high tertile, EFV > 130.7 cm 3 . A total of 180 vessels and ...

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    3. Comparison of In Vivo Assessment of Vulnerable Plaque by 64-Slice Multislice Computed Tomography Versus Optical Coherence Tomography

      Comparison of In Vivo Assessment of Vulnerable Plaque by 64-Slice Multislice Computed Tomography Versus Optical Coherence Tomography
      The aim of this study was to investigate the possibility of 64-slice multislice computed tomography (MSCT) to detect vulnerable plaque derived by optical coherence tomography. From September 2007 through December 2009, 122 lesions in 81 patients were evaluated by 64-slice MSCT and optical coherence tomography. Based on optical coherence tomographic findings, lesions were classified as thin-capped fibroatheroma (TCFA; n = 37) and non-TCFA (n = 85). Mean computed tomographic density value of the lesion was lower and remodeling index was larger in the TCFA group (44.9 ± 19.2 vs 78.7 ± 25.0 HU, p
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    4. In-vivo detection of the frequency and distribution of thin-cap fibroatheroma and ruptured plaques in patients with coronary artery disease: an optical coherence tomographic study

      In-vivo detection of the frequency and distribution of thin-cap fibroatheroma and ruptured plaques in patients with coronary artery disease: an optical coherence tomographic study
      Objectives: The purpose of this study was to assess the prevalence and to quantify the thin-cap fibroatheroma (TCFA) and ruptured plaques in patients with coronary artery disease using optical coherence tomography (OCT). Background: TCFA lesions are the most prevalent precursors of plaque rupture, and are responsible for acute coronary syndromes (ACS). There are limited data regarding the frequency and distribution of TCFA in diseased coronary arteries. Methods: Coronary artery OCT was performed in 78 vessels in 47 patients, with stable angina (SA) or ACS. OCT plaque characteristics were derived using criteria that had been validated earlier. TCFA was defined as ...
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    5. Different Patterns of Vascular Response Between Patients With or Without Diabetes Mellitus After Drug-Eluting Stent Implantation: Optical Coherence Tomographic Analysis

      Different Patterns of Vascular Response Between Patients With or Without Diabetes Mellitus After Drug-Eluting Stent Implantation: Optical Coherence Tomographic Analysis
      Objectives We performed this study to investigate with optical coherence tomography (OCT) the vascular response after sirolimus-eluting stent (SES) implantation between patients with and those without diabetes mellitus (DM). Background The difference in vascular response after SES implantation between patients with and those without DM has not been fully evaluated with OCT. Methods Optical coherence tomography was performed to examine 74 nonrestenotic SES implanted in 63 patients (32 with DM and 31 without DM) at 9 months after SES implantation. For struts showing neointimal coverage, the neointimal thickness on the luminal side of each strut section was measured, and neointimal ...
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    6. Comparative Analysis of Vascular Responses Following Stent Implantation in the Lesion Wth Acute Coronary Syndrome Between Paclitaxel-Eluting and Bare-Metal Stent Using Optical Coherence Tomography

      Background: Safety and feasibility of drug-eluting stent in the lesion with acute coronary syndrome (ACS) is still controversial. Optical coherence tomography (OCT) is a high-resolution intravascular imaging modality, which is expected to visualize microscopic vascular response to coronary intervention. The purpose of this study is to evaluate the difference of vascular responses following stent implantation in the ACS lesions between paclitaxel-eluting stent (PES) and bare-metal stent (BMS) using OCT. Method: Fifty-eight ACS patients who were treated with either PES or BMS (33PESs and 25 BMSs) underwent OCT at 3 months follow-up, and 38 of them (20PESs and 18BMSs) also had ...
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    7. Difference in Neointimal Growth on the Stent Struts Crossing a Side Branch Between Sirolimus-Eluting Stent and Bare-Metal Stent: An Optical Coherence Tomography Analysis

      Difference in Neointimal Growth on the Stent Struts Crossing a Side Branch Between Sirolimus-Eluting Stent and Bare-Metal Stent: An Optical Coherence Tomography Analysis
      Background: A bifurcation lesion has been demonstrated to be the high risk lesion for late stent thrombosis (LST) following drug-eluting stent implantation, resulting from disturbed laminar blood flow and delayed endothelialization of unapposed stent struts. We examined differences in neointimal growth on the stent struts crossing a side branch between sirolimus-eluting stent (SES) and bare-metal stent (BMS) using optical coherence tomography (OCT).. Methods and Results: Of the 41 stents (34 cases) implanted across side branches, 70 struts of 28 SES and 23 struts of 13 BMS, which crossed over a side branch, were analyzed 9 months after stent implantation using ...
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    1-7 of 7
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    Difference in Neointimal Growth on the Stent Struts Crossing a Side Branch Between Sirolimus-Eluting Stent and Bare-Metal Stent: An Optical Coherence Tomography Analysis Different Patterns of Vascular Response Between Patients With or Without Diabetes Mellitus After Drug-Eluting Stent Implantation: Optical Coherence Tomographic Analysis In-vivo detection of the frequency and distribution of thin-cap fibroatheroma and ruptured plaques in patients with coronary artery disease: an optical coherence tomographic study Comparison of In Vivo Assessment of Vulnerable Plaque by 64-Slice Multislice Computed Tomography Versus Optical Coherence Tomography The impact of epicardial fat volume on coronary plaque vulnerability: insight from optical coherence tomography analysis Association of coronary plaque composition and arterial remodelling: A optical coherence tomography study - Corrected Proof Alterations of Hyaluronan Metabolism in Acute Coronary Syndrome: Implications for Plaque Erosion The vascular morphology of melanoma is related to Breslow index: an in vivo study with dynamic optical coherence tomography Optical Coherence Tomography in Glaucoma (Textbook) Aberration-diverse optical coherence tomography for suppression of multiple scattering and speckle Schlemm's canal measured by optical coherence tomography and correlation study in a healthy Caucasian child population Optical coherence tomography angiography and microvascular changes in diabetic retinopathy: a systematic review