1. Articles from Maria Karabut

    1-5 of 5
    1. Combined use of fluorescence cystoscopy and cross-polarization OCT for diagnosis of bladder cancer and correlation with immunohistochemical markers

      Combined use of fluorescence cystoscopy and cross-polarization OCT for diagnosis of bladder cancer and correlation with immunohistochemical markers

      The combined use of fluorescence cystoscopy and cross-polarization optical coherence tomography (CP OCT) with quantitative estimation of the OCT signal was assessed in 92 bladder zones. It demonstrated the diagnostic accuracy in detecting superficial bladder cancer of 93.6%, sensitivity 96.4%, specificity 92.1%, positive predictive value 87% and negative predictive value 97.9%. Quantitative estimation of OCT signal standard deviation in cross-polarization (CP OCT SD index) makes the visual criteria of CP OCT image assessment more objective. The level of CP OCT SD index for diagnosing superficial bladder cancer, including cancer in situ, was 4.32 dB and ...

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    2. Evaluation of oral mucosa collagen condition with cross-polarization optical coherence tomography

      Evaluation of oral mucosa collagen condition with cross-polarization optical coherence tomography

      The goal of the research was analysis of the effect of collagen condition in formation of cross-polarized CP OCT images. We used of the CP OCT technique for studying collagen condition on an example of oral mucosa. Special histologic picrosirius red (PSR) staining of cheek mucosa specimens was used with subsequent assessing of the result of collagen staining in polarized light. High correlation (r = 0.692, p = 0.0001) between OCT signal standard deviation (SD) in cross-polarized images and brightness of PSR stained collagen fibers in cheek mucosa specimens was demonstrated in patients with inflammatory intestine and oral mucosa diseases ...

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    3. Cross polarization optical coherence tomography for diagnosis of oral soft tissues

      Cross polarization optical coherence tomography for diagnosis of oral soft tissues

      We consider the capabilities of cross-polarization OCT (CP OCT) focused on comparison of images resulting from cross-polarization and co-polarization scattering simultaneously for diagnosis of oral soft tissues. CP OCT was done for 35 patients with dental implants and 30 patients with inflammatory intestine diseases. Our study showed good diagnostic capabilities of CP OCT for detecting soft tissue pathology in the oral cavity. The cross-polarized images demonstrate the ability of tissue to depolarize. CP OCT demonstrates clinical capabilities for early diagnosis of inflammatory intestine diseases by the state of oral cavity mucosa and for early detection of gingivitis in patients above ...

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    4. Cross-polarization optical coherence tomography for early bladder-cancer detection: statistical study

      Cross-polarization optical coherence tomography for early bladder-cancer detection: statistical study
      The capabilities of cross-polarization optical coherence tomography (CP OCT) for early bladder-cancer detection are assessed in statistical study and compared with the traditional OCT. Unlike the traditional OCT that demonstrates images only in copolarization, CP OCT acquires images in cross-polarization and copolarization simultaneously. 116 patients with localized flat suspicious lesions in the bladder were enrolled, 360 CP OCT images were obtained and analyzed. CP OCT demonstrated sensitivity 93.7% (vs. 81.2%, <0.0001), specificity 84% (vs. 70.0%, <0.001) and accuracy 85.3% (vs. 71.5%, <0.001) in detecting flat malignant bladder lesions, which is significantly better ...
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    5. Application of optical coherence tomography in the diagnosis of mucositis in patients with head and neck cancer during a course of radio(chemo)therapy

      Objective Mucositis is the most common oral complication of non-surgical therapy (chemotherapy, radiotherapy, and radio(chemo)therapy) in patients with head and neck cancer. Growing evidence indicates that more aggressive treatment regimens improve local tumor control and the survival of patients with locally advanced head and neck cancer. However combined therapy approaches are associated with higher acute toxicity. Currently there are no in vivo methods to visualize microscopic changes of mucosal structure during a course of radio(chemo)therapy and to assess the development and healing of oral mucositis. As a result it has been impossible to predict its severity ...
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    1-5 of 5
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  2. Topics in the News

    1. (5 articles) Nizhny Novgorod State Medical Academy
    2. (5 articles) Natalia D. Gladkova
    3. (5 articles) Elena B. Kiseleva
    4. (5 articles) Maria M. Karabut
    5. (2 articles) Felix I. Feldchtein
    6. (2 articles) Elena V. Zagaynova
    7. (2 articles) Olga S. Streltsova
    8. (1 articles) Institute of Applied Physics
    9. (1 articles) Grigory V. Gelikonov
    10. (1 articles) Imalux
    11. (1 articles) Sungkyunkwan University
    12. (1 articles) Texas A&M University
    13. (1 articles) FDA
    14. (1 articles) University of Southern California
    15. (1 articles) Joon Mo Kim
    16. (1 articles) Brian E. Applegate
    17. (1 articles) Wihan Kim
    18. (1 articles) Javier A. Jo
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    Cross-polarization optical coherence tomography for early bladder-cancer detection: statistical study Cross polarization optical coherence tomography for diagnosis of oral soft tissues Evaluation of oral mucosa collagen condition with cross-polarization optical coherence tomography Combined use of fluorescence cystoscopy and cross-polarization OCT for diagnosis of bladder cancer and correlation with immunohistochemical markers Medical treatment of inflammatory punctual stenosis monitored by anterior segment optical coherence tomography Development and Validation of a Deep Learning System for Diagnosing Glaucoma Using Optical Coherence Tomography Methylene blue-filled biodegradable polymer particles as a contrast agent for optical coherence tomography Optical coherence tomography for thyroid pathology: 3D analysis of tissue microstructure Mathematical Analysis of Texture Indicators for the Segmentation of Optical Coherence Tomography Images Comparison of Current Optical Coherence Tomography Angiography Methods in Imaging Retinal Hemangioblastomas New findings useful for clinical practice using swept-source optical coherence tomography angiography in the follow-up of active ocular toxoplasmosis Ultrafast-laser ablation of polymer multicore fibers enhances biomedical sensing