1. Articles from Laxmi Gella

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    1. Quantitative spectral domain optical coherence tomography thickness parameters in type II diabetes

      Quantitative spectral domain optical coherence tomography thickness parameters in type II diabetes

      Purpose: To elucidate the changes in retinal thickness and individual layer thickness in subjects with diabetic retinopathy (DR) using spectral domain optical coherence tomography (SDOCT). Materials and Methods: A total of 251 eyes from 170 subjects were included in this study. The study sample was subdivided into nondiabetic subjects; subjects with diabetes but no DR; subjects with mild, moderate, and severe nonproliferative DR (NPDR); and proliferative DR. Various retinal thickness parameters were assessed using SDOCT. Results: The mean age of the study population was 55.34 ± 9.02 years (range: 32-80 years) and 56.6% of the subjects were males ...

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    2. Imaging drusens using Spectral Domain Optical Coherence Tomography

      Imaging drusens using Spectral Domain Optical Coherence Tomography

      Purpose The purpose was to evaluate pathological changes of photoreceptor layer and retinal pigment epithelium in eyes with drusens using Spectral Domain Optical Coherence Tomography (SD-OCT). Methods Twenty-nine eyes of 29 patients with (drusens) dry age-related macular degeneration and 43 eyes of 43 controls were included in this study. All subjects underwent complete ophthalmic examination including SD-OCT. Central foveal thickness (CFT), photoreceptor layer (PRL) thickness and retinal pigment epithelial (RPE) thickness were measured and compared between the groups. P value < 0.05 was considered statistically significant. Results Best corrected visual acuity (BCVA) ranged between 20/20 and 20/200. RPE ...

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    3. Spectral domain optical coherence tomography characteristics in diabetic retinopathy

      Spectral domain optical coherence tomography characteristics in diabetic retinopathy

      Purpose: To report the appearance of diabetic retinopathy lesions using spectral domain optical coherence tomography (SD-OCT). Materials and Methods: A total of 287 eyes of 199 subjects were included. All the subjects underwent complete ophthalmic examination including SD-OCT. Results: The appearance of various lesions of diabetic retinopathy and the retinal layers involved were reported. In subjects with macular edema the prevalence of incomplete PVD was 55.6%. Conclusion: SD-OCT brings new insights into the morphological changes of the retina in diabetic retinopathy.

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    4. Macular Thickness Measurements using Copernicus Spectral Domain Optical Coherence Tomography

      Macular Thickness Measurements using Copernicus Spectral Domain Optical Coherence Tomography

      Purpose To provide normal macular thickness measurements using Spectral Domain Optical Coherence Tomography (SDOCT, Copernicus, Optopol Technologies, Zawierci, Poland). Methods Fifty eight eyes of 58 healthy subjects were included in this prospective study. All subjects had comprehensive ophthalmic examination including best-corrected visual acuity (BCVA). All the subjects underwent Copernicus SDOCT. Central foveal thickness (CFT) and photoreceptor layer (PRL) thickness were measured and expressed as mean and standard deviation. Mean retinal thickness for each of the 9 regions defined in the Early Treatment Diabetic Retinopathy Study were reported. The data was compared with published literature in Indians using Stratus and Spectralis ...

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    5. Morphological and functional changes in spectral domain optical coherence tomography and microperimetry in macular microhole variants: Spectral domain optical coherence tomography and microperimetry correlation

      Morphological and functional changes in spectral domain optical coherence tomography and microperimetry in macular microhole variants: Spectral domain optical coherence tomography and microperimetry correlation
      Purpose: To evaluate the relationship between the morphology and retinal function of macular microhole (MMH) variants. Materials and Methods: We evaluated 12 eyes of 11 patients with defects in the IS/OS junction of photoreceptor layer with SD-OCT. All patients underwent comprehensive ophthalmic examination including spectral domain optical coherence tomography (SD-OCT) and microperimetry. Results: The mean logMAR visual acuity in the affected eye was 0.15 ± 0.17 (range 0.00-0.5). Mean horizontal diameter of the MMH was 163 ± 99 μm; the mean retinal sensitivity in the area corresponding to the MMH was 13.79 ± 4.6 dB. Negative ...
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    6. Spectral domain optical coherence tomography and microperimetry in foveal hypoplasia

      Spectral domain optical coherence tomography and microperimetry in foveal hypoplasia
      A case of foveal hypoplasia associated with ocular albinism with anatomic and functional changes by various techniques using spectral domain optical coherence tomography (SD-OCT), microperimeter and confocal scanning laser ophthalmoscope is described. This case highlights the importance of microperimeter in detecting the functional abnormalities of vision and SD-OCT in identifying the retinal laminar abnormalities in foveal hypoplasia.
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    7. Evaluation of In Vivo Human Retinal Morphology and Function in Myopes

      Evaluation of In Vivo Human Retinal Morphology and Function in Myopes
      Purpose: To compare the retinal sensitivity, using Microperimeter and the morphological changes in retinal layers, using Spectral Domain Optical Coherence Tomography (SD-OCT), between myopes and age-matched emmetropes. Methods: Twenty-nine myopic eyes and 29 emmetropic eyes were enrolled in this prospective case control study. All subjects underwent subjective refraction as part of the ophthalmic examination and in addition, SDOCT and Microperimetry were performed. Based on the reflectivity on the OCT cross sections, the thickness of the retinal layers was measured 2.5 mm on either side of the fovea. Results: The mean retinal sensitivity was significantly (p = 0.001) reduced in ...
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    1-7 of 7
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    1. (4 articles) Optopol Technology
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    Evaluation of In Vivo Human Retinal Morphology and Function in Myopes Spectral domain optical coherence tomography and microperimetry in foveal hypoplasia Morphological and functional changes in spectral domain optical coherence tomography and microperimetry in macular microhole variants: Spectral domain optical coherence tomography and microperimetry correlation Spectral domain optical coherence tomography characteristics in diabetic retinopathy Macular Thickness Measurements using Copernicus Spectral Domain Optical Coherence Tomography Imaging drusens using Spectral Domain Optical Coherence Tomography Quantitative spectral domain optical coherence tomography thickness parameters in type II diabetes Impact of Posterior Sclera on Glaucoma Progression in Treated Myopic Normal-Tension Glaucoma Using Reconstructed Optical Coherence Tomographic Images Intravascular Ultrasound and Optical Coherence Tomography in the Procedural Planning and Execution of Left Main Coronary Artery Percutaneous Coronary Intervention Changes in Retinal Vasculature and Thickness after Small Incision Lenticule Extraction with Optical Coherence Tomography Angiography Mapping diurnal variations in choroidal sublayer perfusion in patients with idiopathic epiretinal membrane: an optical coherence tomography angiography study Automatic detection of retinal regions using fully convolutional networks for diagnosis of abnormal maculae in optical coherence tomography images