1. Articles from D. Lorenser

    1-2 of 2
    1. 3D imaging of internal structures of skeletal muscle with an ultrathin side-viewing optical needle probe

      3D imaging of internal structures of skeletal muscle with an ultrathin side-viewing optical needle probe

      Evaluation of degradation in the structure of skeletal muscle is important for the assessment or diagnosis of many myopathies, such as Duchenne muscular dystrophy. Histological analysis is the gold standard to evaluate such degradation but requires excision and fixation of the tissue. This is undesirably invasive in patients and precludes longitudinal study of disease progression in patients or animal models. Optical coherence tomography (OCT) is a high-resolution (∼10μm) imaging modality capable of visualising muscle structure and the morphological changes in muscular dystrophy. However, because of the limited image penetration of OCT (∼2mm), previous studies have been restricted to imaging ...

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    2. Ultrathin side-viewing needle probe for optical coherence tomography

      Ultrathin side-viewing needle probe for optical coherence tomography

      We present the smallest reported side-viewing needle probe for optical coherence tomography (OCT). Design, fabrication, optical characterization, and initial application of a 30-gauge (outer diameter 0.31 mm) needle probe are demonstrated. Extreme miniaturization is achieved by using a simple all-fiber probe design incorporating an angle-polished and reflection-coated fiber-tip beam deflector. When inserted into biological tissue, aqueous interstitial fluids reduce the probe’s inherent astigmatism ratio to 1.8, resulting in a working distance of 300 μm and a depth-of-field of 550 μm with beam diameters below 30 μm. The needle probe was interfaced with an 840 nm spectral-domain OCT ...

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    1-2 of 2
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  2. Topics in the News

    1. (2 articles) University of Western Australia
    2. (2 articles) Dirk Lorenser
    3. (2 articles) Xiaojie Yang
    4. (2 articles) David D. Sampson
    5. (2 articles) Rodney W. Kirk
    6. (1 articles) Robert A. McLaughlin
    7. (1 articles) Kawasaki Medical School
    8. (1 articles) University of Houston
    9. (1 articles) University of Milan
    10. (1 articles) Baylor College of Medicine
    11. (1 articles) Mary E. Dickinson
    12. (1 articles) Manmohan Singh
    13. (1 articles) Shiro Uemura
    14. (1 articles) Teruyoshi Kume
    15. (1 articles) Yoji Neishi
    16. (1 articles) Kirill V. Larin
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    Ultrathin side-viewing needle probe for optical coherence tomography 3D imaging of internal structures of skeletal muscle with an ultrathin side-viewing optical needle probe Anterior Segment Optical Coherence Tomography of Patients With Late-Onset Tunnel Fungal Infections With Endophthalmitis After Cataract Surgery Mechanical properties of the everolimus-eluting bioresorbable vascular scaffold compared to the metallic everolimus-eluting stent Use of Anterior Segment Optical Coherence Tomography to Determine the Position of the Horizontal and Vertical Extraocular Muscles Anterior Segment Optical Coherence Tomography of the Horizontal and Vertical Extraocular Muscles With Measurement of the Insertion to Limbus Distance Impact of stent platform on longitudinal stent deformation: an in vivo frequency domain optical coherence tomography study Early neoatherosclerosis after bioresorbable vascular scaffold implantation: insights from optical coherence tomography Huge positive remodeling and incomplete stent apposition late after Cypher stent implantation: angiography and optical coherence tomography comparison with a Xience V stent in the same patient Optical coherence tomography for embryonic imaging: a review OCT angiography quantitates differences in lesion responses to anti-VEGF therapy SPECTRAL DOMAIN-OPTICAL COHERENCE TOMOGRAPHY IMAGE CONTRAST AND BACKGROUND COLOR SETTINGS INFLUENCE IDENTIFICATION OF RETINAL STRUCTURES