1. Articles from Megan Connors

    1-2 of 2
    1. Characterizing the point spread function of retinal OCT devices with a model eye-based phantom

      Characterizing the point spread function of retinal OCT devices with a model eye-based phantom

      We have designed, fabricated, and tested a nanoparticle-embedded phantom (NEP) incorporated into a model eye in order to characterize the point spread function (PSF) of retinal optical coherence tomography (OCT) devices in three dimensions under realistic imaging conditions. The NEP comprises a sparse distribution of highly backscattering silica-gold nanoshells embedded in a transparent UV-curing epoxy. The commercially-available model eye replicates the key optical structures and focusing power of the human eye. We imaged the model eye-NEP combination with a research-grade spectral domain OCT system designed for in vivo retinal imaging and quantified the lateral and axial PSF dimensions across the ...

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    2. Optical coherence tomography imaging of retinal damage in real time under a stimulus electrode

      Optical coherence tomography imaging of retinal damage in real time under a stimulus electrode

      We have developed a novel method to study the effects of electrical stimulation of the local retina directly under an epiretinal stimulus electrode in real time. Using optical coherence tomography (OCT) and a superfused retinal eyecup preparation, we obtained high-resolution images of the rabbit retina directly under an optically transparent saline-filled fluoropolymer stimulation tube electrode. During OCT imaging, 50 Hz trains of biphasic current pulses 1 ms/phase (23–749 µC cm−2 ph−1) were applied to the retinal surface for 5 min. After imaging, the stimulated regions were stained with the dye propidium iodide (PI) to reveal cytotoxic ...

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    1-2 of 2
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  2. Topics in the News

    1. (2 articles) University of Maryland
    2. (2 articles) FDA
    3. (2 articles) Anant Agrawal
    4. (1 articles) Rice University
    5. (1 articles) Ethan D. Cohen
    6. (1 articles) Yu Chen
    7. (1 articles) Chia-Pin Liang
    8. (1 articles) Physical Sciences Incorporated
    9. (1 articles) British Columbia Cancer Agency
    10. (1 articles) Shanghai Jiao Tong University
    11. (1 articles) Singapore Eye Research Institute
    12. (1 articles) Simon Fraser University
    13. (1 articles) Columbia University
    14. (1 articles) Stephen Lam
    15. (1 articles) Pierre M. Lane
    16. (1 articles) Tien Yin Wong
    17. (1 articles) Giuseppe Querques
    18. (1 articles) Francesco Bandello
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    Optical coherence tomography imaging of retinal damage in real time under a stimulus electrode Characterizing the point spread function of retinal OCT devices with a model eye-based phantom Line-field confocal optical coherence tomography-Practical applications in dermatology and comparison with established imaging methods Optical coherence tomography detection of changes in inner retinal and choroidal thicknesses in patients with early retinitis pigmentosa Feasibility of combined optical coherence tomography and autofluorescence imaging for visualization of needle biopsy placement Characterization of microvascular tortuosity in retinal vein occlusion utilizing optical coherence tomography angiography Evaluation of retinochoroidal tissues in third trimester pregnants: An optical coherence tomography angiography study Evaluation of retinal and choroidal variations in thyroid-associated ophthalmopathy using optical coherence tomography angiography OCTA Study: Retinal Vascular Changes in COVID19 Patients DIABETIC MACULAR ISCHEMIA: Correlation of Retinal Vasculature Changes by Optical Coherence Tomography Angiography and Functional Deficit OCT Risk Factors for 3-Year Development of Macular Complications in eyes with “Resolved” Chronic Central Serous Chorioretinopathy Manipulation of the Endocochlear Potential Reveals Two Distinct Types of Cochlear Nonlinearity