1. Articles from Shuichi Yamamoto

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    1. Determination of Length of Interdigitation Zone by Optical Coherence Tomography and Retinal Sensitivity by Microperimetry and Their Relationship to Progression of Retinitis Pigmentosa

      Determination of Length of Interdigitation Zone by Optical Coherence Tomography and Retinal Sensitivity by Microperimetry and Their Relationship to Progression of Retinitis Pigmentosa

      Purpose. To investigate the annual progression of retinitis pigmentosa (RP) by changes in retinal sensitivity and length of photoreceptor microstructures. Method. The medical records of patients with typical RP followed at Chiba University Hospital were reviewed. The retinal sensitivity was measured by Micro Perimeter-1, and the lengths of the intact external limiting membrane (ELM), ellipsoid zone (EZ), and interdigitation zone (IZ) were measured by spectral-domain optical coherence tomography. The baseline values and annual progression rates were determined. The significance of the correlations among these factors was determined by generalized estimating equation regression analysis. Results . Forty-six eyes of 24 patients who ...

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    2. Correlation between Fourier-Domain Optical Coherence Tomography Parameters and HbA1c Level and Diabetes Duration in Early Stage Diabetic Retinopathy

      Correlation between Fourier-Domain Optical Coherence Tomography Parameters and HbA1c Level and Diabetes Duration in Early Stage Diabetic Retinopathy

      We examined a significant correlation between Fourier-domain optical coherence tomography (FD-OCT) parameters and the glycosylated hemoglobin A1c (HbA1c) level and duration of diabetes mellitus (DM) in patients at the early stage of diabetic retinopathy (DR). Thirty eyes of 30 patients with early stage DR that were examined at the Chiba University Hospital were studied. The macular map 5 (MM5), the retinal nerve fiber layer thickness, and the ganglion cell complex thickness were obtained by FD-OCT. The coefficients of correlation between these parameters and the HbA1c level and the DM duration were determined by Spearman rank correlation. The thickness of the ...

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      Mentions: Optovue
    3. Photoreceptor Impairment and Restoration on Optical Coherence Tomographic Imag

      Photoreceptor Impairment and Restoration on Optical Coherence Tomographic Imag

      With recent development of spectral-domain optical coherence tomography (SD-OCT), the pathological changes of retina can be observed in much greater detail. SD-OCT clearly delineates three highly reflective lines in the outer retina, which are external limiting membrane (ELM), photoreceptor inner and outer segment (IS/OS) junction, and cone outer segment tips (COST) in order from inside. These lines can serve as hallmarks for the evaluation of photoreceptor condition. In retinitis pigmentosa (RP) leading to photoreceptor degeneration, the ELM, IS/OS, and COST lines are shortened with the progression of the disease. In addition, shortening of the ELM, IS/OS and ...

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    4. Photoreceptor impairment on optical coherence tomographic images in patients with retinitis pigmentosa

      Photoreceptor impairment on optical coherence tomographic images in patients with retinitis pigmentosa

      Morphological assessments of the photoreceptors can be useful in estimating the disease progression in retinitis pigmentosa (RP).1–3 Using spectral-domain optical coherence tomography, the external limiting membrane (ELM) and cone outer segment tips (COST) can be clearly detected in addition to photoreceptor inner/outer segment junction (IS/OS). To date, the IS/OS as well as the ELM and COST have been analysed after macular surgery.4 5 In RP patients, however, changes of the COST line and correlations among the IS/OS, ELM and COST lines remain unclear. We have already reported that the IS/OS length was ...

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    5. Foveal Microstructure on Spectral-Domain Optical Coherence Tomographic Images and Visual Function After Macular Hole Surgery

      Foveal Microstructure on Spectral-Domain Optical Coherence Tomographic Images and Visual Function After Macular Hole Surgery
      Purpose: To determine the correlation between the recovery of foveal microstructure and the visual acuity or the foveal sensitivity after idiopathic macular hole (MH) closure.Design: Prospective, consecutive, observational case series.Methods: We studied 43 eyes of 43 patients before and 1, 3, and 6 months after MH surgery. The best-corrected visual acuity (BCVA), the foveal sensitivity measured by MP1 microperimetry, and the photoreceptor inner and outer segment (IS/OS) junction and the external limiting membrane (ELM) determined by spectral-domain optical coherence tomography were investigated.Results: Preoperatively, the lengths of the IS/OS junction defect and the ELM defect were ...
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    6. Macular abnormalities in patients with retinitis pigmentosa: prevalence on OCT examination and outcomes of vitreoretinal surgery

      Macular abnormalities in patients with retinitis pigmentosa: prevalence on OCT examination and outcomes of vitreoretinal surgery
      Purpose: To determine the prevalence of macular abnormalities detected by optical coherence tomography (OCT) in patients with retinitis pigmentosa (RP), and to report the results of pars plana vitrectomy (PPV) in five patients with RP.Methods: OCT images of the macula of 622 eyes of 323 patients with RP were evaluated. All patients had a complete clinical examination, and PPV was performed on two RP patients with a macular hole (MH), two patients with vitreomacular traction (VMT) syndrome, and one patient with cystoid macular oedema (CME).Results: A macular lesion was detected by OCT in 46 eyes (7.4%) of ...
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    7. Correlation of Visual Recovery to Presence of Photoreceptor Inner/Outer Segment Junction in Optical Coherence Images after Epiretinal Membrane Surgery

      Aims: To investigate the relationship between the presence of the photoreceptor inner and outer segment (IS/OS) junction and visual acuity after epiretinal membrane (ERM) surgery. Methods: Seventy eyes of 70 consecutive patients who had undergone vitrectomy for idiopathic ERMs were examined by optical coherence tomography (OCT) preoperatively and at 3 and 6 months postoperatively. The IS/OS junction was graded into three grades. The time course of recovery of the IS/OS junction, central foveal thickness (CFT), and best corrected visual acuity (BCVA) during the postoperative period was studied. Results: A normal IS/OS junction was detected in 47 ...
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    1-7 of 7
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    Macular abnormalities in patients with retinitis pigmentosa: prevalence on OCT examination and outcomes of vitreoretinal surgery Foveal Microstructure on Spectral-Domain Optical Coherence Tomographic Images and Visual Function After Macular Hole Surgery Photoreceptor impairment on optical coherence tomographic images in patients with retinitis pigmentosa Photoreceptor Impairment and Restoration on Optical Coherence Tomographic Imag Correlation between Fourier-Domain Optical Coherence Tomography Parameters and HbA1c Level and Diabetes Duration in Early Stage Diabetic Retinopathy Determination of Length of Interdigitation Zone by Optical Coherence Tomography and Retinal Sensitivity by Microperimetry and Their Relationship to Progression of Retinitis Pigmentosa Postdoctoral opening in optical instrumentation and retinal imaging at University of Illinois at Chicago Detection of intracranial hypertension in children using optical coherence tomography: a systematic review protocol Optical coherence tomography versus intravascular ultrasound for culprit lesion assessment in patients with acute myocardial infarction Insulin-like growth factor-1 levels predict myocardial injury and infarction after elective percutaneous coronary intervention: an optical coherence tomography study Short-term healing response after implantation of the thin-strut, fast-releasing sirolimus-eluting biodegradable polymer-coated Alex Plus stent: optical coherence tomography study Connector sensors for permittivity-based thrombus monitoring in extracorporeal life support