1. Articles from Shu Yen Lee

    1-5 of 5
    1. DIABETIC MACULAR ISCHEMIA Correlation of Retinal Vasculature Changes by Optical Coherence Tomography Angiography and Functional Deficit

      DIABETIC MACULAR ISCHEMIA Correlation of Retinal Vasculature Changes by Optical Coherence Tomography Angiography and Functional Deficit

      Purpose: To examine the relationship between macular microvasculature parameters and functional changes in persons with diabetic retinopathy (DR). Methods: Cross-sectional study of 76 eyes with varying levels of DR. Optical coherence tomography angiography (OCTA) quantified superficial and deep perifoveal vessel densities and foveal avascular zone areas. Retinal sensitivity was measured using microperimetry . Optical coherence tomography angiography parameters and retinal sensitivity were correlated. Results: Deep perifoveal vessel density decreased with increasing severity of DR (adjusted mean 51.93 vs. 49.89 vs. 47.96, P -trend = 0.005). Superficial and deep foveal avascular zone area increased with increasing DR severity (adjusted ...

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    2. Imaging in myopia: potential biomarkers, current challenges and future developments

      Imaging in myopia: potential biomarkers, current challenges and future developments

      Myopia is rapidly increasing in Asia and around the world, while it is recognised that complications from high myopia may cause significant visual impairment. Thus, imaging the myopic eye is important for the diagnosis of sight-threatening complications, monitoring of disease progression and evaluation of treatments. For example, recent advances in high-resolution imaging using optical coherence tomography may delineate early myopic macula pathology, optical coherence tomography angiography may aid early choroidal neovascularisation detection, while multimodal imaging is important for monitoring treatment response. However, imaging the eye with high myopia accurately has its challenges and limitations, which are important for clinicians to ...

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    3. Comparison Of Optical Coherence Tomography Angiographic Changes After Anti–Vascular Endothelial Growth Factor Therapy Alone Or In Combination With Photodynamic Therapy In Polypoidal Choroidal Vasculopathy

      Comparison Of Optical Coherence Tomography Angiographic Changes After Anti–Vascular Endothelial Growth Factor Therapy Alone Or In Combination With Photodynamic Therapy In Polypoidal Choroidal Vasculopathy

      Purpose: To compare changes in optical coherence tomography angiography in eyes with polypoidal choroidal vasculopathy after treatment with anti–vascular endothelial growth factor monotherapy or combined with photodynamic therapy . Methods: This is a longitudinal case-controlled study. The authors performed optical coherence tomography angiography at baseline and Month 3 in patients with treatment-naive polypoidal choroidal vasculopathy undergoing monotherapy (n = 10) or combination therapy (n = 13). We analyzed flow signal within the outer retina and choriocapillaris using automated segmentation. The authors analyzed the presence of pachyvessels using a 10.4- μ m segment through Haller layer . The changes in each layer were compared ...

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    4. COMPARISON OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHIC CHANGES AFTER ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY ALONE OR IN COMBINATION WITH PHOTODYNAMIC THERAPY IN POLYPOIDAL CHOROIDAL VASCULOPATHY

      COMPARISON OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHIC CHANGES AFTER ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY ALONE OR IN COMBINATION WITH PHOTODYNAMIC THERAPY IN POLYPOIDAL CHOROIDAL VASCULOPATHY

      Purpose: To compare changes in optical coherence tomography angiography in eyes with polypoidal choroidal vasculopathy after treatment with anti-vascular endothelial growth factor monotherapy or combined with photodynamic therapy. Methods: This is a longitudinal case-controlled study. The authors performed optical coherence tomography angiography at baseline and Month 3 in patients with treatment-naive polypoidal choroidal vasculopathy undergoing monotherapy (n = 10) or combination therapy (n = 13). We analyzed flow signal within the outer retina and choriocapillaris using automated segmentation. The authors analyzed the presence of pachyvessels using a 10.4-[mu]m segment through Haller layer. The changes in each layer were compared ...

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    5. Enhanced Visualization of Myopic Macular Changes With Three-Dimensional OCT

      Enhanced Visualization of Myopic Macular Changes With Three-Dimensional OCT
      This observational case series presents three eyes of three myopic patients to illustrate the pathomorphologic features of the myopic macular changes using three-dimensional optical coherence tomography (OCT). The OCT system records the interferometric information using a Fourier-domain spectrometer method, with an acquisition rate of 20,000 axial scans/second, an axial resolution of 5 μm, and a lateral resolution of 20 μm. Three-dimensional images of the macular pathology and corresponding simultaneous acquisition of OCT fundus photographs were obtained for all patients. Three-dimensional OCT imaging using the Fourier-domain system has enabled unprecedented precise views of macular pathology, facilitating understanding and visualization ...
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    1-5 of 5
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  2. Topics in the News

    1. (4 articles) Singapore Eye Research Institute
    2. (2 articles) National University of Singapore
    3. (2 articles) Tien Yin Wong
    4. (1 articles) Medical University of Vienna
    5. (1 articles) Tokyo Medical & Dental University
    6. (1 articles) Columbia University
    7. (1 articles) Nanyang Technological University
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    9. (1 articles) Gunma University
    10. (1 articles) University of Illinois at Urbana-Champaign
    11. (1 articles) Kobe University Graduate School of Medicine
    12. (1 articles) Toshiro Shinke
    13. (1 articles) Corrado Tamburino
    14. (1 articles) Hiromasa Otake
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