1. Articles from Paul Hahn

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    1. Argus II retinal prosthesis malrotation and repositioning with intraoperative optical coherence tomography in a posterior staphyloma

      Argus II retinal prosthesis malrotation and repositioning with intraoperative optical coherence tomography in a posterior staphyloma

      Introduction: The Argus II retinal prosthesis may improve visual function in patients with severe vision loss from retinitis pigmentosa. Optimal centration of the electrode array over the macula is important to achieve optimal visual results. Argus tack malrotation is a novel entity that may be encountered during placement, especially in patients with posterior staphyloma. Methods: Retrospective case review. Results: During tacking of the electronics array a clockwise rotation occurred resulting in malposition. We hypothesize this was secondary to undue rotation or posterior pressure applied during tack insertion in conjunction with placement over a previously unrecognized posterior staphyloma. Intraoperative optical coherence ...

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    2. Intrasurgical Human Retinal Imaging With Manual Instrument Tracking Using a Microscope-Integrated Spectral-Domain Optical Coherence Tomography Device

      Intrasurgical Human Retinal Imaging With Manual Instrument Tracking Using a Microscope-Integrated Spectral-Domain Optical Coherence Tomography Device

      Purpose: : To characterize the first in-human intraoperative imaging using a custom prototype spectral-domain microscope-integrated optical coherence tomography (MIOCT) device during vitreoretinal surgery with instruments in the eye. Methods: : Under institutional review board approval for a prospective intraoperative study, MIOCT images were obtained at surgical pauses with instruments held static in the vitreous cavity and then concurrently with surgical maneuvers. Postoperatively, MIOCT images obtained at surgical pauses were compared with images obtained with a high-resolution handheld spectral-domain OCT (HHOCT) system with objective endpoints, including acquisition of images acceptable for analysis and identification of predefined macular morphologic or pathologic features. Results: : Human ...

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    3. Novel microscope-integrated stereoscopic display for intrasurgical optical coherence tomography

      Novel microscope-integrated stereoscopic display for intrasurgical optical coherence tomography

      The first generation of intrasurgical optical coherence tomography (OCT) systems displayed OCT data onto a separate computer monitor, requiring surgeons to look away from the surgical microscope. In order to provide real-time OCT feedback without requiring surgeons to look away during surgeries, recent prototype research and commercial intrasurgical OCT systems have integrated heads-up display (HUD) systems into the surgical microscopes to allow the surgeons to access the OCT data and the surgical field through the oculars concurrently. However, all current intrasurgical OCT systems with a HUD are only capable of imaging through one ocular limiting the surgeon’s depth perception ...

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    4. Preclinical Evaluation and Intraoperative Human Retinal Imaging With A High-Resolution Microscope-Integrated Spectral Domain Optical Coherence Tomography Device

      Preclinical Evaluation and Intraoperative Human Retinal Imaging With A High-Resolution Microscope-Integrated Spectral Domain Optical Coherence Tomography Device

      Purpose: The authors have recently developed a high-resolution microscope-integrated spectral domain optical coherence tomography (MIOCT) device designed to enable OCT acquisition simultaneous with surgical maneuvers. The purpose of this report is to describe translation of this device from preclinical testing into human intraoperative imaging. Methods: Before human imaging, surgical conditions were fully simulated for extensive preclinical MIOCT evaluation in a custom model eye system. Microscope-integrated spectral domain OCT images were then acquired in normal human volunteers and during vitreoretinal surgery in patients who consented to participate in a prospective institutional review board-approved study. Microscope-integrated spectral domain OCT images were obtained ...

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    5. Unprocessed real-time imaging of vitreoretinal surgical maneuvers using a microscope-integrated spectral-domain optical coherence tomography system

      Unprocessed real-time imaging of vitreoretinal surgical maneuvers using a microscope-integrated spectral-domain optical coherence tomography system

      BACKGROUND: We have recently developed a microscope-integrated spectral-domain optical coherence tomography (MIOCT) device towards intrasurgical cross-sectional imaging of surgical maneuvers. In this report, we explore the capability of MIOCT to acquire real-time video imaging of vitreoretinal surgical maneuvers without post-processing modifications. METHODS: Standard 3-port vitrectomy was performed in human during scheduled surgery as well as in cadaveric porcine eyes. MIOCT imaging of human subjects was performed in healthy normal volunteers and intraoperatively at a normal pause immediately following surgical manipulations, under an Institutional Review Board-approved protocol, with informed consent from all subjects. Video MIOCT imaging of live surgical manipulations was ...

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    6. The Use of Optical Coherence Tomography in Intraoperative Ophthalmic Imaging

      The Use of Optical Coherence Tomography in Intraoperative Ophthalmic Imaging
      Optical coherence tomography (OCT) has transformed diagnostic ophthalmic imaging but until recently has been limited to the clinic setting. The development of spectral-domain OCT (SD-OCT), with its improved speed and resolution, along with the development of a handheld OCT scanner, enabled portable imaging of patients unable to sit in a conventional tabletop scanner. This handheld SD-OCT unit has proven useful in examinations under anesthesia and, more recently, in intraoperative imaging of preoperative and postoperative manipulations. Recently, several groups have pioneered the development of novel OCT modalities, such as microscope-mounted OCT systems. Although still immature, the development of these systems is ...
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    1-7 of 7
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  2. Topics in the News

    1. (7 articles) Duke University
    2. (7 articles) Paul V. Hahn
    3. (6 articles) Joseph A. Izatt
    4. (5 articles) Cynthia A. Toth
    5. (2 articles) Anthony N. Kuo
    6. (2 articles) Oscar Carrasco-Zevallos
    7. (2 articles) Bioptigen
    8. (1 articles) Ramiro S. Maldonado
    9. (1 articles) Sina Farsiu
    10. (1 articles) University of Tübingen
    11. (1 articles) University of Western Australia
    12. (1 articles) Tufts University
    13. (1 articles) University of Michigan
    14. (1 articles) FDA
    15. (1 articles) Barry Cense
    16. (1 articles) Jerome Sherman
    17. (1 articles) Optovue
    18. (1 articles) Carl Zeiss Meditec
    19. (1 articles) Optos
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    The Use of Optical Coherence Tomography in Intraoperative Ophthalmic Imaging Unprocessed real-time imaging of vitreoretinal surgical maneuvers using a microscope-integrated spectral-domain optical coherence tomography system Preclinical Evaluation and Intraoperative Human Retinal Imaging With A High-Resolution Microscope-Integrated Spectral Domain Optical Coherence Tomography Device Novel microscope-integrated stereoscopic display for intrasurgical optical coherence tomography Intrasurgical Human Retinal Imaging With Manual Instrument Tracking Using a Microscope-Integrated Spectral-Domain Optical Coherence Tomography Device Argus II retinal prosthesis malrotation and repositioning with intraoperative optical coherence tomography in a posterior staphyloma Intra-operative microscope-integrated swept-source optical coherence tomography guided placement of Argus II retinal prosthesis Phenotyping of Mouse Models with OCT Retinal imaging with optical coherence tomography and low‐loss adaptive optics using a 2.8‐mm beam size Two-year outcomes of a pilot glaucoma suspect telemedicine monitoring program Next-level imaging puts optometry on front line of diabetes diagnosis Hamamatsu develops bright supercontinuum source