1. Articles from Syozi Nakashima

    1-8 of 8
    1. A pilot study to assess the morphology and progression of non-carious cervical lesions

      A pilot study to assess the morphology and progression of non-carious cervical lesions

      Objective This longitudinal pilot study aimed to morphologically and quantitatively investigate the progress of non-carious cervical lesions (NCCLs) by using swept-source optical coherence tomography (SS-OCT). Methods The samples examined comprised sets of NCCL epoxy resin replicas obtained from 10 lesions in 6 patients who attended annual dental visits over 4 or 5 years. SS-OCT images of the replicas were analyzed in terms of the maximum depth (D max ) and corresponding vertical width (VW) − using an image analyzer to estimate progression of the NCCLs over time. Results It was found that differences between wedge- and saucer-shaped lesions were morphologically distinguished well ...

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    2. Optical coherence tomography for evaluation of enamel and protective coatings

      Optical coherence tomography for evaluation of enamel and protective coatings

      Optical coherence tomography (OCT) is an interferometric imaging technique. This study aimed to employ OCT to evaluate four different resin-based materials including a coating containing glass-ionomer filler and calcium, a giomer, and two fluoride-releasing self-etch resins. The coating and its underlying and adjacent enamel were monitored using swept-source OCT (center wavelength: 1330 nm) at baseline, after 5,000 thermal cycles, and after 1, 4 and 7 days of demineralization (pH 4.5). The coatings showed different thicknesses (60–250 micrometers) and various levels of structural and interfacial integrity. OCT could detect a demineralization inhibition zone adjacent to the edge of ...

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    3. Monitoring remineralization of enamel subsurface lesions by optical coherence tomography

      Monitoring remineralization of enamel subsurface lesions by optical coherence tomography

      Optical coherence tomography (OCT) is a potential clinical tool for enamel lesion monitoring. Swept-source OCT findings were compared with cross-sectional nanohardness findings of enamel. Subsurface bovine enamel lesions in three groups were subjected to (1) deionized water (control), (2) phosphoryl oligosaccharide of calcium (POs-Ca) or (3) POs-Ca with 1 ppm fluoride for 14 days. B-scans images were obtained at 1310-nm center wavelength on sound, demineralized and remineralized areas after 4, 7, and 14 days. The specimens were processed for cross-sectional nanoindentation. Reflectivity from enamel that had increased with demineralization decreased with remineralization. An OCT attenuation coefficient parameter ( μ t ), derived based ...

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    4. Monitoring of enamel lesion remineralization by optical coherence tomography: an alternative approach towards signal analysis

      Monitoring of enamel lesion remineralization by optical coherence tomography: an alternative approach towards signal analysis

      Early detection, monitoring and remineralization repair of enamel lesions are top research priorities in the modern dentistry focusing on minimal intervention concept for caries management. We investigate the use of swept-source optical coherence tomography system (SS-OCT) without polarization-sensing at 1319 nm wavelength developed for clinical dentistry (Dental OCT System Prototype 2, Panasonic Healthcare Co., Ltd., Japan) in quantitative assessment of artificial enamel lesions and their remineralization. Bovine enamel blocks were subjected to demineralization to create subsurface lesions approximately 130 μm in depth over 2 weeks, and subjected to remineralization in solution containing bioavailable calcium and 1ppm fluoride at pH 6 ...

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    5. Effect of hydration on assessment of early enamel lesion using swept-source optical coherence tomography

      Effect of hydration on assessment of early enamel lesion using swept-source optical coherence tomography

      Establishing reproducible methodologies for assessment of early enamel lesions using optical coherence tomography (OCT) appears to be challenging. This in vitro study longitudinally evaluated the subsurface enamel lesion progression after 3, 9 and 15 days by cross-sectional scanning using 1310 nm centered swept-source OCT (SS-OCT) under hydrated and dry conditions. The positive difference between the depth-integrated OCT signals at dry and hydrated conditions were calculated and adopted as dehydration parameter (DH). A linear regression was found between DH and the square root of demineralization time (R2 = 0.99). Significant differences were found in DH between sound and demineralized enamel, and ...

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    6. Longitudinal assessment of subsurface artificial root caries lesions by optical coherence tomography in comparison with transverse microradiography

      Longitudinal assessment of subsurface artificial root caries lesions by optical coherence tomography in comparison with transverse microradiography

      We previously demonstrated that a swept-source optical coherence tomography system (SS-OCT) without polarization-sensing could quantitatively estimate the progress of cavitated dentin lesions in vitro. The purpose of the current study was to investigate the ability to estimate the lesion development in non-cavitated dentin lesions with a surface layer. Bovine root dentin specimens were subjected to different periods of demineralization (1 to 14 days). Cross-sectional images of the specimens before and after the demineralization were captured by SS-OCT at 1310 nm center wavelength. Following each period, the specimens were cut into sections for transverse microradiography (TMR) and correlations between SS-OCT data ...

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    7. Relationship between refractive index and mineral content of enamel and dentin using SS-OCT and TMR

      Relationship between refractive index and mineral content of enamel and dentin using SS-OCT and TMR

      The aim of this work was to investigate relationship between refractive index (n) and mineral content (MC) (vol %) of enamel and dentin using swept-source optical coherence tomography (SS-OCT) and transverse microradiography (TMR). Enamel and dentin blocks were partitioned into three regions. The middle partition of each sample was covered with a nail polish to protect the sound area during exposure to the treatment solutions. Samples were demineralized in a demineralizing solution, which was refreshed once a week, for 2 months. One window was covered with acid-resistant varnish, leaving the other window exposed; the samples were placed in a solution for ...

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    8. Estimation of lesion progress in artificial root caries by swept source optical coherence tomography in comparison to transverse microradiography

      Estimation of lesion progress in artificial root caries by swept source optical coherence tomography in comparison to transverse microradiography

      This study aimed to investigate whether swept source optical coherence tomography (SS-OCT) could estimate the lesion depth and mineral loss quantitatively without the use of polarization sensitivity, and to examine a relationship between OCT data and transverse microradiography (TMR) lesion parameters. Twenty-four bovine root dentin specimens were allocated to three groups of 4-, 7-, and 14-day demineralization. Cross-sectional images of the specimens before and after the demineralization were captured by OCT at 1319 nm center wavelength. Following the demineralization, these specimens were cut into sections for TMR analysis. Correlations between the OCT data and TMR lesion parameters were examined. TMR ...

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    1-8 of 8
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  2. Topics in the News

    1. (8 articles) Junji Tagami
    2. (8 articles) Yasunori Sumi
    3. (8 articles) Syozi Nakashima
    4. (7 articles) National Center for Geriatrics and Gerontology in Japan
    5. (7 articles) Yasushi Shimada
    6. (7 articles) Alireza Sadr
    7. (6 articles) Tokyo Medical & Dental University
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    Estimation of lesion progress in artificial root caries by swept source optical coherence tomography in comparison to transverse microradiography Longitudinal assessment of subsurface artificial root caries lesions by optical coherence tomography in comparison with transverse microradiography Relationship between refractive index and mineral content of enamel and dentin using SS-OCT and TMR Effect of hydration on assessment of early enamel lesion using swept-source optical coherence tomography Monitoring of enamel lesion remineralization by optical coherence tomography: an alternative approach towards signal analysis Monitoring remineralization of enamel subsurface lesions by optical coherence tomography Optical coherence tomography for evaluation of enamel and protective coatings A pilot study to assess the morphology and progression of non-carious cervical lesions Intravascular Imaging-Guided Percutaneous Coronary Intervention: A Universal Approach for Optimization of Stent Implantation Clinical Usefulness of a Novel Optical Coherence Tomography Procedure, “Low Molecular Weight Dextran Infusion Followed by Catheter PUSH (D-PUSH)” Optical Coherence Tomography to Guide Percutaneous Coronary Intervention of the Left Main Coronary Artery: the LEMON study Impact of optical coherence tomography findings on clinical outcomes in ST-segment elevation myocardial infarction patients: a MATRIX (Minimizing Adverse Hemorrhagic Events by Trans-radial Access Site and angioX) OCT sub-study