1. Articles from Fang Wang

    1-11 of 11
    1. Optical Coherence Tomography Evaluation of Carotid Artery Stenosis and Stenting in Patients With Previous Cervical Radiotherapy

      Optical Coherence Tomography Evaluation of Carotid Artery Stenosis and Stenting in Patients With Previous Cervical Radiotherapy

      Objectives: Cervical radiotherapy can lead to accelerated carotid artery stenosis, increased incidence of stroke, and a higher rate of in-stent restenosis in irradiated patients. Our objective was to reveal the morphological characteristics of radiation-induced carotid stenosis (RICS) and the stent-vessel interactions in patients with previous cervical radiotherapy by optical coherence tomography (OCT). Materials and methods: Between November 2017 and March 2019, five patients with a history of cervical radiotherapy were diagnosed with severe carotid artery stenosis and underwent carotid artery stenting (CAS). OCT was conducted before and immediately after the carotid stent implantation. Two patients received OCT evaluation of carotid ...

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    2. Evaluation of an OCT-AI-Based Telemedicine Platform for Retinal Disease Screening and Referral in a Primary Care Setting

      Evaluation of an OCT-AI-Based Telemedicine Platform for Retinal Disease Screening and Referral in a Primary Care Setting

      Purpose: To evaluate the performance of a telemedicine platform integrated with optical coherence tomography (OCT) and artificial intelligence (AI) techniques for retinal disease screening and referral. Methods: We constructed an OCT-AI-based telemedicine platform and deployed it at four primary care stations located in Jing'an district, Shanghai, to detect retinal disease cases among aged groups and refer them to Shanghai Tenth People's Hospital (TENTH Hospital). Two ophthalmologists jointly graded the data set collected from this pilot application, and then the performance of this platform was analyzed from multiple aspects. Results: This study included 1257 participants between July 2020 and ...

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    3. Optical coherence tomography: evaluating the effects of stent boost subtract imaging on stent underexpansion in STEMI patients

      Optical coherence tomography: evaluating the effects of stent boost subtract imaging on stent underexpansion in STEMI patients

      Background: To evaluate the effect of stent boost subtract (SBS) imaging on stent underexpansion during percutaneous coronary intervention (PCI) in patients with acute ST-segment elevation myocardial infarction (STEMI) by optical coherence tomography (OCT). Methods: One hundred thirty-eight STEMI patients who underwent drug-eluting stent (DES) implantation were prospectively recruited and divided into the SBS group (69 cases) and the CAG group (69 cases) according to whether SBS was used to guide PCI. Finally, OCT was performed on all enrolled patients, and the OCT results were used as the gold standard to evaluate the impact of standard SBS technology on stent underexpansion ...

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    4. Macular vascular changes in pregnant women with gestational diabetes mellitus by optical coherence tomography angiography

      Macular vascular changes in pregnant women with gestational diabetes mellitus by optical coherence tomography angiography

      Background: Retinal capillary is vulnerable to diabetes, whether gestational diabetes mellitus (GDM) eyes without clinical retinopathy have capillary abnormalities has not been well studied. To observe the microvasculature changes in eyes of GDM women compared with normoglycemic pregnant women and non-pregnant women by optical coherence tomography-angiography (OCT-A). Methods: GDM women, age-matched normoglycemic pregnant women and non-pregnant women were included in this study. All subjects were examined by OCT-A, vascular density and macular foveal parameters were measured automatically. Results: Thirty eight non-pregnant women (NC group), thirty pregnant women without GDM (PC group), and thirty one GDM women (GDM group) were included ...

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    5. Assessment of three successive treatments of ranibizumab on neovascular macular degeneration by OCT angiography

      Assessment of three successive treatments of ranibizumab on neovascular macular degeneration by OCT angiography

      In the present study, the efficacy of three consecutive anti-VEGF treatments in patients with neovascular macular degeneration (nAMD) was assessed by optical coherence tomography angiography (OCT-A). A total of 23 eyes with nAMD were treated with intravitreal injections (IVIs) of ranibizumab once a month for three consecutive months. There were eight follow-up time-points: Prior to the initial IVI and on days 1, 3, 7, 14, 30, 60 and 90 after the first IVI. The follow-up examinations consisted of measurements of the best-corrected visual acuity (BCVA), the height of retinal pigmented epithelium detachment (RPED), the greatest linear dimension (GLD), choroidal neovascularization ...

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    6. Superficial Calcification With Rotund Shape Is Associated With Carotid Plaque Rupture: An Optical Coherence Tomography Study

      Superficial Calcification With Rotund Shape Is Associated With Carotid Plaque Rupture: An Optical Coherence Tomography Study

      Background: Plaque rupture is an important etiology for symptomatic carotid stenosis. The role of calcification in the plaque vulnerability has been controversial. We aimed to detect the geometric features of calcifications in carotid plaque and to examine its association with plaque rupture. Methods: Optical coherence tomography assessment of carotid plaque was performed in 88 patients. Calcification shape was evaluated through quantitative measurements of the long and short axis, area size, circumference, calcification arc, and longitudinal length. Calcification location was analyzed through the distance to the lumen. Furthermore, we developed idealized fluid-structure interaction models to investigate the association of calcification shape ...

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    7. Optical coherence tomography evaluation of vertebrobasilar artery stenosis: case series and literature review

      Optical coherence tomography evaluation of vertebrobasilar artery stenosis: case series and literature review

      Background Intracranial vertebrobasilar artery stenosis is an important cause of ischemic stroke. With its high resolution, intravascular optical coherence tomography (OCT) provides detailed assessment of vessel wall features. It is widely applied to identify high-risk plaque in the cardiovascular system, but its use in the intracranial artery has been limited. Objective To explore, in this pilot study, the usefulness of OCT in imaging of the intracranial artery wall. Methods Between November 2017 and July 2018, four patients with severe intracranial vertebrobasilar artery stenosis were enrolled for preintervention OCT evaluation of the lesion artery. Stenosis was present in the basilar artery ...

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    8. Cholesterol Crystals are Associated with Carotid Plaque Vulnerability: An Optical Coherence Tomography Study

      Cholesterol Crystals are Associated with Carotid Plaque Vulnerability: An Optical Coherence Tomography Study

      Objective: Vulnerable carotid plaque is associated with cerebrovascular events. Cholesterol crystals are often seen in the atherosclerotic plaques. However, the potential role of cholesterol crystals in carotid plaques destabilization is unknown. We aimed to identify the association between cholesterol crystals and carotid plaque vulnerability. Methods: Optical coherence tomography assessment of carotid plaque was performed in 95 patients. Clinical characteristics and plaque morphology were examined. The differences in plaque characteristics (thrombus, calcification, neovascularization, and macrophage accumulations) and clinical parameters (age, symptom, coronary heart disease, total cholesterol, triglycerides, and C-reactive protein) between patients with or without cholesterol crystals were analyzed with multivariate ...

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    9. Optical coherence tomography angiography characteristics of acute retinal arterial occlusion

      Optical coherence tomography angiography characteristics of acute retinal arterial occlusion

      Background To characterize the vascular changes in eyes within the acute phase of retinal arterial occlusion (RAO) by optical coherence tomography angiography (OCT-A) imaging. Methods This was a retrospective, observational study. Nineteen patients with RAO (symptom onset within 7 days) and 19 age and sex-matched normal control individuals were included. A comprehensive ophthalmic examination and OCT-A examination were conducted for all the patients. Results The vessel density of the superficial capillary plexus (SCP), deep capillary plexus (DCP), and area with a width of 300 μm around the FAZ (FD-300) was significantly reduced in RAO patients compared with that in the ...

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    10. Interocular Symmetry of Vascular Density and Association with Central Macular Thickness of Healthy Adults by Optical Coherence Tomography Angiography

      Interocular Symmetry of Vascular Density and Association with Central Macular Thickness of Healthy Adults by Optical Coherence Tomography Angiography

      In order to analyze the interocular correlation of vascular density, foveal avascular zone (FAZ) size, central macular thickness (CMT), and to investigate the relationship between vascular density and CMT in normal eyes, retinal vascular density in superficial capillary plexus (SCP), deep capillary plexus (DCP) and choriocapillaris (CC) networks, FAZ size, and CMT were visualized by optical coherence tomography (OCT) angiography. A total of 174 eyes of 87 normal Chinese subjects were enrolled in the study. The results showed that FAZ and CMT measurements are not statistically significant between right and left eyes, but right eyes had higher vascular density in ...

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    11. Measurement of the Limbus-insertion Distance in Adult Strabismus Patients with Anterior Segment Optical Coherence Tomography

      Measurement of the Limbus-insertion Distance in Adult Strabismus Patients with Anterior Segment Optical Coherence Tomography
      Purpose: To determine the ability of the anterior segment optical coherence tomography (AS-OCT) in measuring the distance from the corneoscleral limbus to the insertion site of the horizontal extraocular muscles in adult patients with strabismus. Methods: A total of 16 strabismus patients were recruited for this study. The limbus-insertion distances of the horizontal rectus muscles were measured with AS-OCT preoperatively and calipers intraoperatively. The intraclass correlation coefficient (ICC), Pearson's correlation coefficients and Bland-Altman plots were utilized to evaluate the degree of agreement between the two methods of measurements. Results: Measurements of the limbus-insertion distances were taken on 37 muscles ...
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    1-11 of 11
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  2. Topics in the News

    1. (3 articles) Nanjing University of Science and Technology
    2. (1 articles) Capital Medical University
    3. (1 articles) Wenzhou Medical College
    4. (1 articles) San Raffaele Scientfic Institute
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    Measurement of the Limbus-insertion Distance in Adult Strabismus Patients with Anterior Segment Optical Coherence Tomography Interocular Symmetry of Vascular Density and Association with Central Macular Thickness of Healthy Adults by Optical Coherence Tomography Angiography Optical coherence tomography angiography characteristics of acute retinal arterial occlusion Cholesterol Crystals are Associated with Carotid Plaque Vulnerability: An Optical Coherence Tomography Study Optical coherence tomography evaluation of vertebrobasilar artery stenosis: case series and literature review Superficial Calcification With Rotund Shape Is Associated With Carotid Plaque Rupture: An Optical Coherence Tomography Study Assessment of three successive treatments of ranibizumab on neovascular macular degeneration by OCT angiography Macular vascular changes in pregnant women with gestational diabetes mellitus by optical coherence tomography angiography Evaluation of an OCT-AI-Based Telemedicine Platform for Retinal Disease Screening and Referral in a Primary Care Setting Optical Coherence Tomography Evaluation of Carotid Artery Stenosis and Stenting in Patients With Previous Cervical Radiotherapy Intraoperative Optical Coherence Tomography in Idiopathic Macular Epiretinal Membrane Surgery Quantitative approaches in multimodal fundus imaging: State of the art and future perspectives