1. Articles from Eric K. Chin

    1-8 of 8
    1. West Nile Virus Chorioretinitis With Foveal Involvement Evolution of Lesions on Optical Coherence Tomography

      West Nile Virus Chorioretinitis With Foveal Involvement Evolution of Lesions on Optical Coherence Tomography

      Purpose: To describe the clinical course of foveal West Nile virus (WNV) chorioretinitis with longitudinal spectral domain optical coherence tomography (SD-OCT) imaging. Methods: Case report. Results: A 41-year-old man with diabetes mellitus presented with flashes and floaters of both eyes (OU) and decreased vision of the right eye (OD) 2 weeks after being discharged from a local hospital. He had been treated for WNV meningoencephalitis, and he recovered systemically with supportive therapy. Ophthalmic examination revealed WNV chorioretinitis bilaterally, with predominantly foveal involvement OD. His best-corrected visual acuity (BCVA) was 8/200 OD and 20/20 of the left eye (OS ...

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    2. Staging of Macular Telangiectasia: Power-Doppler Optical Coherence Tomography and Macular Pigment Optical Density

      Staging of Macular Telangiectasia: Power-Doppler Optical Coherence Tomography and Macular Pigment Optical Density

      Purpose: Two methods were used to study the stages of macular telangiectasia (MacTel): Power-Doppler optical coherence tomography (PD-OCT) which allows imaging of retinal circulation in three-dimensions, and macular pigment optical density (MPOD) which quantifies the distribution of macular carotenoids. Methods: Among 49 patients with MacTel identified, 12 eyes (6 patients) with MacTel and 7 age-matched control eyes (7 patients) were imaged with a custom-built Fourier-domain OCT instrument to acquire PD-OCT images. MPOD was measured using heterochromatic flicker photometry in 10 eyes (5 patients) with MacTel and compared to 44 age-matched control eyes (44 patients). Clinical staging of MacTel was based ...

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    3. FIVE-YEAR FOLLOW-UP OF MACULAR MORPHOLOGIC CHANGES AFTER RHEGMATOGENOUS RETINAL DETACHMENT REPAIR: Fourier Domain OCT Findings

      FIVE-YEAR FOLLOW-UP OF MACULAR MORPHOLOGIC CHANGES AFTER RHEGMATOGENOUS RETINAL DETACHMENT REPAIR: Fourier Domain OCT Findings

      Purpose: To evaluate serially long-term macular morphologic changes after successful macula-involving rhegmatogenous retinal detachment repair and correlate changes with macular function. Methods: Repeat Fourier domain optical coherence tomography (FD OCT) imaging and microperimetry (MP-1) testing of 8 of the initial cohort of 17 eyes studied 5 years earlier. Results: The mean follow-up after rhegmatogenous retinal detachment repair was 3.4 months (range, 1-8.5 months) for the first FD OCT and 5 years (range, 3.75-5.75 years) for the follow-up FD OCT. The final postoperative best-corrected visual acuity mean was 20/201 (range, 20/20 to counting fingers). Six ...

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    4. Anterior Segment OCT and Confocal Microscopy Findings in Atypical Corneal Intraepithelial Neoplasia

      Anterior Segment OCT and Confocal Microscopy Findings in Atypical Corneal Intraepithelial Neoplasia

      Purpose: To report a case of biopsy-proven corneal intraepithelial neoplasia (CIN) diagnosed and followed clinically using high-resolution anterior segment optical coherence tomography (AS-OCT) and in vivo confocal microscopy (IVCM). Methods: Observational case report. Results: A 57-year-old man presented with decreased vision in the right eye for 2 months before presentation. His best-corrected visual acuity was 20/70 in the affected eye, and the slit-lamp examination revealed superficial opacification of the anterior cornea originating from the temporal limbus with a "leopard-spot" pattern more centrally. The lesion was excised at his 2-month follow-up, and the histological examination revealed squamous dysplasia consistent with ...

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    5. Feature Of The Week 2/19/12: UC Davis Researchers Investigate the Reproducibility of Macular Thickness Measurements Among Five Commercial OCT Instruments

      Feature Of The Week 2/19/12: UC Davis Researchers Investigate the Reproducibility of Macular Thickness Measurements Among Five Commercial OCT Instruments

      There are now over 10 ophthalmic OCT instrument makers selling into the commercial OCT ophthalmology market. Today there are both time-domain, spectral-domain, and swept-source commercial OCT systems. There have been various studies comparing different aspects of these instruments.  One such study was by researchers at the University of California Davis Eye Center compared five instruments (Stratus/Zeiss, Cirrus/Zeiss, Spectralis/Heidelberg, RTVue/Optovue, and SD-OCT/Topcon in their central macular thickness measurements.For more information see recent Article. Courtesy Sussana Park and  Eric Chin from UC Davis.

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    6. Reproducibility of Macular Thickness Measurement Among Five OCT Instruments: Effects of Image Resolution, Image Registration, and Eye Tracking

      Reproducibility of Macular Thickness Measurement Among Five OCT Instruments: Effects of Image Resolution, Image Registration, and Eye Tracking

      BACKGROUND AND OBJECTIVE: To study the effect of image resolution, eye tracking, and image registration on central macular thickness reproducibility (rCMT) among spectral-domain and time-domain optical coherence tomography (SD-OCT and TD-OCT) instruments. PATIENTS AND METHODS: Seventy-six eyes were imaged (44 normal, 32 maculopathy) either twice using four SD-OCT and one TD-OCT devices or three times using Spectralis SD-OCT (with and without eye tracking) (Heidelberg Engineering, Inc., Heidelberg, Germany). Cirrus images (Carl Zeiss Meditec, Dublin, CA) were further analyzed with three-point image registration. RESULTS: All instruments had superior rCMT in normal versus pathologic eyes (P < .001). No difference in rCMT was noted among instruments in normal eyes (P = .92), but TD-OCT was superior to SD-OCT (P = .017) in pathologic eyes. Cirrus image registration improved rCMT for normal eyes (P = .04), with borderline improvement in pathologic eyes (P = .06). Spectralis eye tracking improved rCMT in normal (P = .01) and pathologic (P = .004) eyes. CONCLUSION: Higher image resolution with SD-OCT may not improve rCMT, but image registration and eye tracking options may improve rCMT.

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    7. Comparison of Retinal Nerve Fiber Layer and Central Macular Thickness Measurements Among Five Different Optical Coherence Tomography Instruments in Patients With Multiple Sclerosis and Optic Neuritis

      Comparison of Retinal Nerve Fiber Layer and Central Macular Thickness Measurements Among Five Different Optical Coherence Tomography Instruments in Patients With Multiple Sclerosis and Optic Neuritis

      Background: To compare the mean central macular thickness (CMT) and the mean average optic nerve retinal nerve fiber layer (RNFL) thickness in the eyes of patients with a history of optic neuritis and/or multiple sclerosis (MS) using 5 commercially available optical coherence tomography (OCT) instruments. Methods: Cross-sectional study including 46 patients (92 eyes) with a history of optic neuritis and/or MS. Both eyes were imaged on the same day with 5 OCT instruments: 1 time-domain OCT (Stratus) and 4 different Fourier-domain (spectral-domain) OCT (3D OCT-1000, Cirrus, RTVue-100, and Spectralis). Results: Twenty-five patients (50 eyes) were included in the ...

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    8. Prospective Comparison of Cirrus and Stratus Optical Coherence Tomography for Quantifying Retinal Thickness

      Prospective Comparison of Cirrus and Stratus Optical Coherence Tomography for Quantifying Retinal Thickness

      Purpose: To compare Cirrus Fourier-domain optical coherence tomography (OCT) with Stratus time-domain OCT for imaging retinal diseases and quantifying retinal thickness (RT) of all nine OCT zones, central macular thickness, and average macular thickness in eyes with and without macular edema.Design: Prospective comparison between two OCT systems.Methods: RT measurements were performed in 120 eyes of 60 patients suspected of having increased retina thickness using both Stratus and Cirrus OCT on the same day. Twenty-one eyes had both 512 × 128 and 200 × 200 Cirrus cube scans done.Results: Data from 101 eyes (53 patients) were analyzed; 46 eyes (45 ...

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    1-8 of 8
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    1. (7 articles) Eric K. Chin
    2. (6 articles) UC Davis
    3. (5 articles) Susanna S. Park
    4. (3 articles) Optovue
    5. (3 articles) Topcon Medical Systems
    6. (3 articles) Carl Zeiss Meditec
    7. (3 articles) Heidelberg Engineering
    8. (2 articles) John S. Werner
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    Prospective Comparison of Cirrus and Stratus Optical Coherence Tomography for Quantifying Retinal Thickness Comparison of Retinal Nerve Fiber Layer and Central Macular Thickness Measurements Among Five Different Optical Coherence Tomography Instruments in Patients With Multiple Sclerosis and Optic Neuritis Reproducibility of Macular Thickness Measurement Among Five OCT Instruments: Effects of Image Resolution, Image Registration, and Eye Tracking Feature Of The Week 2/19/12: UC Davis Researchers Investigate the Reproducibility of Macular Thickness Measurements Among Five Commercial OCT Instruments Anterior Segment OCT and Confocal Microscopy Findings in Atypical Corneal Intraepithelial Neoplasia FIVE-YEAR FOLLOW-UP OF MACULAR MORPHOLOGIC CHANGES AFTER RHEGMATOGENOUS RETINAL DETACHMENT REPAIR: Fourier Domain OCT Findings Staging of Macular Telangiectasia: Power-Doppler Optical Coherence Tomography and Macular Pigment Optical Density West Nile Virus Chorioretinitis With Foveal Involvement Evolution of Lesions on Optical Coherence Tomography Evaluating Retinal and Choroidal Perfusion Changes After Ocular Massage of Healthy Eyes Using Optical Coherence Tomography Angiography Dermal Epidermal Junction Detection for Full-Field Optical Coherence Tomography Data of Human Skin by Deep Learning OctNET: A Lightweight CNN for Retinal Disease Classification from Optical Coherence Tomography Images The Association between Tear Film Thickness as Measured with OCT and Symptoms and Signs of Dry Eye Disease: A Pooled Analysis of 6 Clinical Trials