1. Articles from Lauren S. Talman

    1-2 of 2
    1. Monocular and binocular low-contrast visual acuity and optical coherence tomography in pediatric multiple sclerosis

      Monocular and binocular low-contrast visual acuity and optical coherence tomography in pediatric multiple sclerosis

      Background Low-contrast letter acuity and optical coherence tomography (OCT) capture visual dysfunction and axonal loss in adult-onset multiple sclerosis (MS), and have been proposed as secondary outcome metrics for therapeutic trials. Clinical trials will soon be launched in pediatric MS, but such outcome metrics have not been well-validated in this population. Objectives To determine whether MS onset during childhood and adolescence is associated with measurable loss of visual acuity and thinning of the retinal nerve fiber layer (RNFL), whether such features are noted only in the context of clinical optic nerve inflammation (optic neuritis, ON) or are a feature of ...

      Read Full Article
    2. Retinal Ganglion Cell Layer Volumetric Assessment by Spectral-Domain Optical Coherence Tomography in Multiple Sclerosis: Application of a High-Precision Manual Estimation Technique

      Retinal Ganglion Cell Layer Volumetric Assessment by Spectral-Domain Optical Coherence Tomography in Multiple Sclerosis: Application of a High-Precision Manual Estimation Technique
      Background: Neuronal loss in the retina has been demonstrated pathologically in eyes of patients with multiple sclerosis (MS). In vivo, MS eyes have reduced total macular volumes by optical coherence tomography (OCT). Using a high-resolution spectral-domain OCT, this pilot study used a manual method to measure ganglion cell layer (GCL) volumes and to determine the relation of these volumes to visual function in MS eyes. Methods: Sixteen eyes of 8 patients with MS and 8 eyes of 5 disease-free control participants were studied using fast macular OCT scans performed with Spectralis OCT (Heidelberg Engineering). Visual function tests of low-contrast letter ...
      Read Full Article
    1-2 of 2
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Topics in the News

    1. (3 articles) Avinger
    2. (2 articles) University of Pennsylvania
    3. (2 articles) Johns Hopkins University
    4. (2 articles) UT Southwestern Medical Center
    5. (2 articles) Peter A. Calabresi
    6. (2 articles) Laura J. Balcer
    7. (2 articles) Elliot M. Frohman
    8. (2 articles) John B. Simpson
    9. (1 articles) Amy Conger
    10. (1 articles) Heidelberg Engineering
    11. (1 articles) Zeiss Stratus OCT
    12. (1 articles) Heidelberg Spectralis
    13. (1 articles) Oregon Health & Science University
    14. (1 articles) Dirk-Uwe G. Bartsch
    15. (1 articles) David Huang
    16. (1 articles) Jun Geun Shin
    17. (1 articles) Jonghyun Eom
    18. (1 articles) William R. Freeman
    19. (1 articles) Optovue
    20. (1 articles) Heidelberg Spectralis
  3. Popular Articles

  4. Picture Gallery

    Retinal Ganglion Cell Layer Volumetric Assessment by Spectral-Domain Optical Coherence Tomography in Multiple Sclerosis: Application of a High-Precision Manual Estimation Technique Monocular and binocular low-contrast visual acuity and optical coherence tomography in pediatric multiple sclerosis Outer Retinal Layers Alterations in Chronic Central Serous Chorioretinopathy: Spectral Domain-OCT and Fundus Autofluorescence Findings Recanalization of Organized Thrombi Demonstrated by Coronary CT Angiography Compared With OCT An All-Fiber-Optic Combined System of Noncontact Photoacoustic Tomography and Optical Coherence Tomography The Repeatability of Retinal Layer Thickness Measurements with Spectral-Domain Optical Coherence Tomography in Normal Eyes Assessment of Vascular Response after Stent Implantation by Intracoronary Optical Coherence Tomograph In vivo assessment of optical properties of basal cell carcinoma and differentiation of BCC subtypes by high-definition optical coherence tomography Optical Coherence Tomography Classification and Correlation With Tuberous Sclerosis Complex Comparison Between Full-Depth Imaging Spectral Domain Optical Coherence Tomography and Swept-Source Optical Coherence Tomography Optical sensing system for cochlear implant surgery Occlusion-crossing devices, atherectomy devices, and imaging