1. Articles from Daniel D. Esmaili

    1-4 of 4
    1. Spectral-Domain Optical Coherence Tomography as an Indicator of Fluorescein Angiography Leakage from Choroidal Neovascularization

      Spectral-Domain Optical Coherence Tomography as an Indicator of Fluorescein Angiography Leakage from Choroidal Neovascularization

      Purpose: To evaluate spectral-domain optical coherence tomography (SD-OCT) findings that predict angiographic leakage in choroidal neovascularization (CNV). Methods: SD-OCT and fluorescein angiography (FA) images of 93 eyes of 93 patients were retrospectively analyzed. All patients were previously treated with anti-vascular endothelial growth factor agents for CNV from age-related macular degeneration. FA images were analyzed to assess the presence of leakage. SD-OCT images were analyzed to identify the overall presence of fluid, as well as specific patterns of fluid presentation including intraretinal cystic spaces (ICS), retinal pigment epithelium detachment (PED), and neurosensory detachment (NSD). The presence of ultrastructural features such as ...

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    2. Displayed Reflectivity Of Choroidal Neovascular Membranes By Optical Coherence Tomography Correlates With Presence of Leakage By Fluorescein Angiography

      Displayed Reflectivity Of Choroidal Neovascular Membranes By Optical Coherence Tomography Correlates With Presence of Leakage By Fluorescein Angiography

      Purpose: To evaluate and correlate the displayed optical reflectivity of choroidal neovascularization (CNV) subretinal material on spectral-domain optical coherence tomography with the presence of dye leakage on fluorescein angiography (FA).Methods: Thirty-nine eyes of 39 patients with a diagnosis of predominantly classic CNV from age-related macular degeneration underwent simultaneous spectral-domain optical coherence tomography and FA imaging. Eight patients had a newly diagnosed untreated CNV. Thirty-one patients had already been treated with anti-vascular endothelial growth factor agents. In 18 of these eyes, CNV lesions showed persistent leakage on FA. In 13 eyes, CNV lesions did not show leakage by FA. Subretinal ...

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    3. Artifacts In Automatic Retinal Segmentation Using Different Optical Coherence Tomography Instruments

      Purpose: The purpose of this study was to compare and evaluate artifact errors in automatic inner and outer retinal boundary detection produced by different time-domain and spectral-domain optical coherence tomography (OCT) instruments.Methods: Normal and pathologic eyes were imaged by six different OCT devices. For each instrument, standard analysis protocols were used for macular thickness evaluation. Error frequencies, defined as the percentage of examinations affected by at least one error in retinal segmentation (EF-exam) and the percentage of total errors per total B-scans, were assessed for each instrument. In addition, inner versus outer retinal boundary delimitation and central (1,000 ...

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    4. In Vivo Three-Dimensional Imaging of Neovascular Age-Related Macular Degeneration Using Optical Frequency Domain Imaging at 1050 nm

      PURPOSE. To assess the application of optical frequency domain imaging (OFDI) at 1050 nm for the detection of choroidal neovascularization (CNV) in age-related macular degeneration (AMD) and its response to treatment. Three patients presenting with blurred vision and exudative AMD were imaged before and after anti-VEGF treatment with ranibizumab. METHODS. The patients were imaged with OFDI, a swept-source–based, high-speed optical coherence tomography (OCT) system developed at the Wellman Center for Photomedicine. A center wavelength of 1050 nm was used that has been demonstrated to provide better imaging of the deeper structures of the retina below the RPE, such as ...
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    1-4 of 4
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  2. Topics in the News

    1. (3 articles) Massachusetts Eye and Ear Infirmary
    2. (3 articles) Harvard University
    3. (3 articles) University of Milan
    4. (3 articles) Mario Cigada
    5. (3 articles) Andrea Giani
    6. (3 articles) Giovanni Staurenghi
    7. (1 articles) Massachusetts General Hospital
    8. (1 articles) Teresa C. Chen
    9. (1 articles) Johannes F. de Boer
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    11. (1 articles) Institute of Applied Physics
    12. (1 articles) Medical University of Vienna
    13. (1 articles) Kyungpook National University
    14. (1 articles) Singapore Eye Research Institute
    15. (1 articles) University of Western Australia
    16. (1 articles) Stefan G. Sacu
    17. (1 articles) Brendan F. Kennedy
    18. (1 articles) Yongyang Huang
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