1. Articles from Tairo Kurita

    1-6 of 6
    1. Impact on Optical Coherence Tomographic Coronary Findings of Fluvastatin Alone versus Fluvastatin+ Ezetimibe

      Impact on Optical Coherence Tomographic Coronary Findings of Fluvastatin Alone versus Fluvastatin+ Ezetimibe

      Although lipid lowering therapy by statin and ezetimibe has been reported to provide greater reduction in low-density lipoprotein cholesterol (LDL-C) levels than statin monotherapy, the effect of supplemental therapy on plaque stabilization is yet to be fully elucidated. Cap thickness of fibroatheroma evaluated by Optical coherence tomography (OCT) is a major determinant of vulnerable plaque. The primary objective of this study is to evaluate the effect of ezetimibe in addition to fluvastatin on progression of coronary atherosclerotic plaque evaluated by OCT. Sixty-three angina pectoris patients with intermediate, non-culprit, lipid-rich plaque lesions evaluated by OCT were enrolled. The patients were divided ...

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    2. Impact of Cholesterol Metabolism on Coronary Plaque Vulnerability of Target Vessels : A Combined Analysis of Virtual Histology Intravascular Ultrasound and Optical Coherence Tomography

      Impact of Cholesterol Metabolism on Coronary Plaque Vulnerability of Target Vessels : A Combined Analysis of Virtual Histology Intravascular Ultrasound and Optical Coherence Tomography

      Objectives The aim of this study was to evaluate the relationship between cholesterol metabolism and coronary plaque vulnerability. Background Cholesterol homeostasis, defined as the balance between absorption and synthesis, influences the progression of coronary atherosclerosis. Methods Consecutive stable angina pectoris patients (N = 80) not receiving any lipid-lowering therapy were divided into 2 groups based on the presence of in vivo thin cap fibroatheroma (TCFA) in de novo target vessels assessed by the combined use of virtual histology intravascular ultrasound and optical coherence tomography. Results Patients with in vivo TCFA (n = 42) showed a higher campesterol-to-lathosterol ratio (3.36 [interquartile range ...

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    3. Morphological differences of tissue characteristics between early, late, and very late restenosis lesions after first generation drug-eluting stent implantation: an optical coherence tomography study

      Morphological differences of tissue characteristics between early, late, and very late restenosis lesions after first generation drug-eluting stent implantation: an optical coherence tomography study

      Aims Restenosis of drug-eluting stents (DESs) might be different from that of bare metal stent restenosis in diverse ways including mechanisms and time course; however, these have not been fully examined. To gain insight into the mechanisms and time course of DES restenosis, we evaluated the characteristics of restenotic lesions of first generation DES using optical coherence tomography (OCT). Methods and results We compared the morphological characteristics of early in-stent restenosis (<1 year: E-ISR, n = 43), late ISR (1–3 years: L-ISR, n = 22), and very late ISR (>3 years: VL-ISR, n = 21). OCT qualitative restenotic tissue analysis included the ...

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    4. Response to Letter Regarding Article, "Impact of Frequency-Domain Optical Coherence Tomography Guidance for Optimal Coronary Stent Implantation in Comparison With Intravascular Ultrasound Guidance"

      Response to Letter Regarding Article, "Impact of Frequency-Domain Optical Coherence Tomography Guidance for Optimal Coronary Stent Implantation in Comparison With Intravascular Ultrasound Guidance"

      We appreciate the valuable comments by Garcia-Garcia et al regarding our article.1 We agree with the comments on our limitations about study design especially with regard to criteria of the procedure. First, the efficacy of distal protection devices in native coronary arteries is still controversial, and criteria regarding usage of this device are not defined yet. However, we believe this device could be helpful for prevention of distal embolus in certain cases as we have sometimes experienced, and optical frequency-domain imaging (OFDI) is helpful to predict such cases. Making use of the criteria of this study, distal protection was ...

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    5. Impact of Frequency-Domain Optical Coherence Tomography Guidance for Optimal Coronary Stent Implantation in Comparison With Intravascular Ultrasound Guidance

      Impact of Frequency-Domain Optical Coherence Tomography Guidance for Optimal Coronary Stent Implantation in Comparison With Intravascular Ultrasound Guidance

      Background—Frequency-domain optical coherence tomography (FD-OCT) is a novel, high resolution intravascular imaging modality. Intravascular ultrasound (IVUS) is a widely used conventional imaging modality for achieving optimal stent deployment. The aim of this study was to evaluate the impact of FD-OCT guidance for coronary stent implantation compared with IVUS guidance. Methods and Results—A total of 70 patients with de novo coronary artery lesions and either unstable or stable angina pectoris were enrolled in this randomized study (optical coherence tomography [OCT] group: n=35, IVUS group: n=35). In the OCT group, stent implantation was performed under FD-OCT guidance alone ...

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    6. Difference of Tissue Characteristics Between Early and Very Late Restenosis Lesions After Bare-Metal Stent Implantation: An Optical Coherence Tomography Study

      Difference of Tissue Characteristics Between Early and Very Late Restenosis Lesions After Bare-Metal Stent Implantation: An Optical Coherence Tomography Study
      Background—Although in-stent restenosis (ISR) after bare-metal stent (BMS) implantation peaks in the early phase, very late (VL) ISR occasionally is observed beyond a few years after BMS implantation. To date, this mechanism has not been fully clarified. Methods and Results—We compared the morphological characteristics of VL-ISR (>5 years, without restenosis within the first year) (n=43) to those of early (E) ISR (within the first year) (n=39) using optical coherence tomography (OCT). Qualitative restenotic tissue analysis included assessment of tissue structure (homogeneous or heterogeneous), presence of microvessels, disrupted intima with cavity, and intraluminal material and was performed ...
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    1-6 of 6
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    Difference of Tissue Characteristics Between Early and Very Late Restenosis Lesions After Bare-Metal Stent Implantation: An Optical Coherence Tomography Study Impact of Frequency-Domain Optical Coherence Tomography Guidance for Optimal Coronary Stent Implantation in Comparison With Intravascular Ultrasound Guidance Response to Letter Regarding Article, "Impact of Frequency-Domain Optical Coherence Tomography Guidance for Optimal Coronary Stent Implantation in Comparison With Intravascular Ultrasound Guidance" Morphological differences of tissue characteristics between early, late, and very late restenosis lesions after first generation drug-eluting stent implantation: an optical coherence tomography study Impact of Cholesterol Metabolism on Coronary Plaque Vulnerability of Target Vessels : A Combined Analysis of Virtual Histology Intravascular Ultrasound and Optical Coherence Tomography Impact on Optical Coherence Tomographic Coronary Findings of Fluvastatin Alone versus Fluvastatin+ Ezetimibe Software Postdoctoral Position in Optical imaging at Casey Eye Institute, Oregon Health & Science University Automated classification of optical coherence tomography images for the diagnosis of oral malignancy in the hamster cheek pouch Corneal Topographic Analysis of Patients With Mooren Ulcer Using 3-Dimensional Anterior Segment Optical Coherence Tomography A survey of current and anticipated use of standard and specialist equipment by UK optometrists Optical coherence Doppler tomography for quantitative cerebral blood flow imaging This is Your Brain's Blood Vessels on Cocaine