1. Articles from Holger Lubatschowski

    1-8 of 8
    1. Control of Femtosecond Thin-flap LASIK Using OCT in Human Donor Eyes

      PURPOSE Thin-flap keratomileusis is a procedure that minimizes LASIK flap thickness to preserve both the corneal epithelium and the maximum residual stroma. This study investigated the usefulness of optical coherence tomography (OCT) as a tool in guiding the femtosecond laser in the creation of a thin flap in human eyes in a non-randomized case series. METHODS In a private research laboratory, an in vitro investigation was performed on human autopsy eyes. Five human cadaver eyes, unsuitable for transplantation, underwent flap creation with a femtosecond laser. The laser procedure was controlled in real-time with an OCT system (Thorlabs HL AG) to ...
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    2. In Vivo Application and Imaging of Intralenticular Femtosecond Laser Pulses for the Restoration of Accommodation

      PURPOSE According to the Helmholtz theory of accommodation, one major cause of the development of presbyopia is the increasing sclerosis of the crystalline lens. One concept for regaining the elasticity of the sclerosing lens is intralenticular treatment by femtosecond laser pulses. METHODS The feasibility of applying and imaging in vivo microincisions by femtosecond laser pulses was evaluated in five rabbit lenses with a new high repetition rate (100 kHz) femtosecond laser unit. The treated eyes were monitored using optical coherence tomography (OCT) and Scheimpflug imaging for localizing and studying the tissue effects of the incisions. The rabbits were investigated preoperatively ...
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    3. Clinical value of optical coherence tomography in laryngology

      Background. Optical coherence tomography (OCT) is a new, noninvasive imaging technology for the evaluation of superficial lesions. The objective of this study is to evaluate microlaryngoscopy in combination with OCT compared with microlaryngoscopy alone (ie, without OCT) in supplying a specific diagnosis, predicting invasive tumor growth and epithelial dysplasia in the larynx. Methods. This was a prospective study including 217 laryngeal lesions in a total of 193 patients undergoing surgery. Intraoperative suspicion diagnosis gained by microlaryngoscopy with and without OCT was compared with conventional histopathology after excisional biopsy. Results. Microlaryngoscopy with OCT supplied a specific diagnosis in 89% of cases ...
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    4. Femtosecond laser microsurgery system controlled by optical coherence tomography

      Femtosecond laser microsurgery system controlled by optical coherence tomography
      Due to nonlinear interaction with optical transparent and scattering samples the femtosecond technology is a very useful tool for high precision micro surgery on biological tissues. At the same time femtosecond lasers are ideal light sources for imaging methods such as optical coherence tomography ( ... [Proc. SPIE Int. Soc. Opt. Eng. 6881, 688106 (2008)] published Fri Feb 15, 2008.
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    5. Significance of optical coherence tomography in the assessment of laryngeal lesions

      Optical coherence tomography (OCT) is a new promising imaging modality in laryngology as yet of undetermined value. The objective of the present study was to evaluate the ability of this noninvasive method to make a reliable prediction of diagnosis in laryngeal disease. In a prospective study, 225 b ... [Proc. SPIE Int. Soc. Opt. Eng. 6842, 68421O (2008)] published Fri Feb 8, 2008.
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    6. Optical coherence tomography monitoring of vocal fold femtosecond laser microsurgery

      Surgery of benign pathological alterations of the vocal folds results in permanent disphonia if the bounderies of the vocal fold layers are disregarded. Precise cutting with a femtosecond laser (fs-laser) combined with simultanous imaging of the layered structure enables accurate resections with respect to the layer boundaries. Earlier works demonstrated the capability of optical coherence tomography (OCT) for utilization on vocal folds. The layered structure can be imaged with a spatial resolution of 10-20µm up to a depth of 1.5mm. The performance of fs-laser cutting was analyzed on extracted porcine vocal folds with OCT monitoring. Histopathological sections of the ...
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    7. Optical coherence tomography controlled femtosecond laser microsurgery system

      Optical coherence tomography controlled femtosecond laser microsurgery system
      Due to nonlinear interaction with optical transparent samples the femtosecond technology is a very useful tool for high precision micro surgery on biological tissues. At the same time femtosecond lasers are ideal light sources for imaging methods such as optical coherence tomography (OCT) due to the broad spectrum of the laser, which is necessary for creating ultra short pulses. Using OCT structures within biological tissues can be imaged non invasive with a resolution within the low µm-range. The combined use of an ultra short pulse laser for cutting of biological tissues as well as imaging via OCT is a very ...
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    8. Laser machining of materials

      A device for machining a material with ultrashort laser pulses is described. This device comprises: (a) a device (1) for generating a sequence of first laser pulses, where the first laser pulses each have a duration of less than 300 picoseconds and the repetition rate for the first laser pulses is in the range between 100 kHz and 1 GHz, (b) a converter (2) for converting a first set of the sequence of first laser pulses into a sequence of second laser pulses for application to and for machining of the material, where the second laser pulses each have a ...
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    1-8 of 8
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  2. Topics in the News

    1. (8 articles) Laser Zentrum Hannover
    2. (8 articles) Holger Lubatschowski
    3. (3 articles) Ole Massow
    4. (3 articles) Henning Wisweh
    5. (1 articles) Hannover Medical School
    6. (1 articles) University of Bonn
    7. (1 articles) Thorlabs
    8. (1 articles) UCLA
    9. (1 articles) Massachusetts General Hospital
    10. (1 articles) Centre Hospitalier Intercommunal de Créteil
    11. (1 articles) Harvard University
    12. (1 articles) University of Maryland
    13. (1 articles) Harbin Medical University
    14. (1 articles) Imperial College London
    15. (1 articles) Aarhus University
    16. (1 articles) University of Southern California
    17. (1 articles) Eric H. Souied
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