1. Articles from Michalina Góra

    1-22 of 22
    1. Postdoctoral Research Fellowship in Biomedical Optics at CNRS/Strasbourg University

      Postdoctoral Research Fellowship in Biomedical Optics at CNRS/Strasbourg University

      Applicants are invited to apply for a postdoctoral researcher position in optical imaging systems for biomedical applications. The project involves the development of the novel catheter-based OCT imaging system to enhance the robotized interventional endoscope for diagnosing and treatment of diseases in the digestive system. The successful candidate will work with the research group supported by the ATIP-Avenir grant awarded by the French National Center for Scientific Research (CNRS) and the French National Institute of Health and Medical Research (INSERM). The group is focused on highly interdisciplinary projects that bridge photonics and robotics to improve performance of microscopic imaging modalities ...

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    2. Static and dynamic crystalline lens accommodation evaluated using quantitative 3-D OCT

      Static and dynamic crystalline lens accommodation evaluated using quantitative 3-D OCT

      Custom high-resolution high-speed anterior segment spectral domain Optical Coherence Tomography (OCT) provided with automatic quantification and distortion correction algorithms was used to characterize three-dimensionally (3-D) the human crystalline lens in vivo in four subjects, for accommodative demands between 0 to 6 D in 1 D steps. Anterior and posterior lens radii of curvature decreased with accommodative demand at rates of 0.73 and 0.20 mm/D, resulting in an increase of the estimated optical power of the eye of 0.62 D per diopter of accommodative demand. Dynamic fluctuations in crystalline lens radii of curvature, anterior chamber depth and ...

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    3. 3D imaging for faster diagnosis of esophageal disease

      3D imaging for faster diagnosis of esophageal disease

      A tethered capsule that is swallowed by the patient offers a quick and pain-free method of screening and diagnosing gastrointestinal diseases. Diagnosing gastrointestinal (GI) diseases usually involves endoscopy, combining an invasive probe and video imaging or other optical methods. While effective, this method often causes patient discomfort and typically requires anesthesia, making it costly and time-consuming. Here we describe a new option for screening using a swallowable optomechanically engineered pill that rapidly provides 3D microscopic images of the gastrointestinal tract. The process is pain-free, so there is no need for anesthesia, and enables quick diagnosis of esophageal diseases.

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    4. Interobserver Agreement for the Detection of Barrett’s Esophagus with Optical Frequency Domain Imagin

      Interobserver Agreement for the Detection of Barrett’s Esophagus with Optical Frequency Domain Imagin

      Background Optical frequency domain imaging (OFDI) is a second-generation form of optical coherence tomography (OCT) providing comprehensive cross-sectional views of the distal esophagus at a resolution of ~7 μm. Aim Using validated OCT criteria for squamous mucosa, gastric cardia mucosa, and Barrett’s esophagus (BE), the objective of this study was to determine the inter- and intra-observer agreements by a large number of OFDI readers for differentiating these tissues. Methods OFDI images were obtained from nine subjects undergoing screening and surveillance for BE. Sixty-four OFDI image regions of interest were randomly selected for review. A training set of 19 images ...

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    5. Optical frequency domain imaging system and catheters for volumetric imaging of the human esophagus

      Optical frequency domain imaging system and catheters for volumetric imaging of the human esophagus

      Barrett's esophagus (BE) is a metaplastic disorder that can undergo dysplastic progression, leading to esophageal adenocarcinoma. Upper endoscopy is the standard of care for screening for BE, but this technique has a relatively low diagnostic accuracy and high cost due to the requirement of conscious sedation. Optical frequency domain imaging (OFDI) is a high-speed imaging modality that generates cross-sectional images of tissues with a resolution of approximately 10µm that is sufficient for detecting microscopic tissue architecture. In combination with a balloon-centering catheter, this method enables BE diagnosis over the entire distal esophagus.   Full Text: PDFReferences S. H. Yun ...

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    6. Corneal topography with high-speed swept source OCT in clinical examination

      Corneal topography with high-speed swept source OCT in clinical examination
      We present the applicability of high-speed swept source (SS) optical coherence tomography (OCT) for quantitative evaluation of the corneal topography. A high-speed OCT device of 108,000 lines/s permits dense 3D imaging of the anterior segment within a time period of less than one fourth of second, minimizing the influence of motion artifacts on final images and topographic analysis. The swept laser performance was specially adapted to meet imaging depth requirements. For the first time to our knowledge the results of a quantitative corneal analysis based on SS OCT for clinical pathologies such as keratoconus, a cornea with superficial ...
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    7. Imaging of the lens capsule with an ultrahigh-resolution spectral optical coherence tomography prototype based on a femtosecond laser

      Aim To demonstrate the applicability of ultrahigh-speed, ultrahigh-resolution spectral optical coherence tomography (SOCT) to cross-sectional imaging of the capsular bag in vivo. Methods The ultrahigh-speed and ultrahigh-resolution SOCT prototype was designed and constructed at Nicolaus Copernicus University (Torun, Poland). To obtain an ultrahigh speed up to 100 000 lines/s a new spectrometer with fast CMOS line-scan camera was built. A femtosecond laser with a central wavelength of 780 nm and =160 nm enabled imaging with an axial resolution of 2.3 µm and lateral resolution of 10 µm in tissue. Lens capsules of two healthy eyes were examined with ...
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    8. Ultra high-speed swept source OCT imaging of the anterior segment of human eye at 200 kHz with adjustable imaging range

      Ultra high-speed swept source OCT imaging of the anterior segment of human eye at 200 kHz with adjustable imaging range
      We present an application of in vivo anterior segment imaging of the human eye with an ultrahigh speed swept source OCT instrument. For this purpose, a dedicated OCT system was designed and constructed. This instrument enables axial zooming by automatic reconfiguration of spectral sweep range; an enhanced imaging range mode enables imaging of the entire anterior segment while a high axial resolution mode provides detailed morphological information of the chamber angle and the cornea. The speed of 200,000 lines/s enables high sampling density in three-dimensional imaging of the entire cornea in 250 ms promising future applications of OCT ...
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    9. Four-dimensional visualization with optical coherence tomography

      Four-dimensional visualization with optical coherence tomography
      A new system for ultrahigh-speed imaging of the anterior segment of the eye retains micrometer resolution. The widespread development of improved imaging modalities dedicated to visualizing the anterior segment of the eye has regenerated interest in ophthalmic studies.1–3 Among methods such as slit-scanning topography, Scheimpflug imaging, and high-frequency ultrasonography, optical coherence tomography (OCT) has generated particular attention. OCT emerged from investigations into low-coherence interferometry and optical reflectometry.4 As an echo technique, it can be thought of as similar to ultrasound. However, as OCT is based on light, it can deliver much higher resolution, similar to low-power microscopy ...
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    10. Characterization of Glass Surface Morphology by Optical Coherence Tomography

      Characterization of Glass Surface Morphology by Optical Coherence Tomography
      Optical coherence tomography (OCT) has been applied as a tool to assist glass conservators and researchers in monitoring and predicting the evolution of glass surfaces – the crucial issue in the correct maintenance of historic glass. This technique of examination of the internal structure of objects with infrared light originates from diagnostic medicine but application to any object that weakly absorbs and/or scatters light is straightforward. Since the intensity of the examining light is very low, this remote method is also completely non-invasive. The object is usually penetrated by a narrow beam of light of broad spectrum. The distribution of ...
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    11. Optical coherence tomography holds promise for conserving art

      Optical coherence tomography holds promise for conserving art
      OCT has migrated successfully from medical imaging to materials science, where it is used online to monitor varnish removal from paintings. Noninvasive examinations of human patients and art objects share more than the important modus operandi of ‘do no harm.’ Soon after medical x-rays were discovered, they were applied to inspect the underlying layers of paintings. More recently, that extended to the newer modality of x-ray tomography. Now, optical coherence tomography (OCT), which acquires and processes optical signals to produce high-quality 3D images, has entered the picture. Medical OCT was first described in 1991,1 and reports of its use ...
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    12. Anterior segment imaging with Spectral OCT system using a high-speed CMOS camera

      Anterior segment imaging with Spectral OCT system using a high-speed CMOS camera
      We describe a new ultrahigh speed Spectral OCT instrument making use of a CMOS camera and demonstrate high quality in vivo imaging of the anterior segment of the human eye. The high flexibility of the designed imaging system allows a wide range of imaging protocols. Two- and three-dimensional high ... [Opt. Express 17, 4842-4858 (2009)]
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    13. Comparison of reflectivity maps and outer retinal topography in retinal disease by 3-D Fourier domain optical coherence tomography

      Comparison of reflectivity maps and outer retinal topography in retinal disease by 3-D Fourier domain optical coherence tomography
      We demonstrate and compare two image processing methods for visualization and analysis of three-dimensional optical coherence tomography (OCT) data acquired in eyes with different retinal pathologies. A method of retinal layer segmentation based on a multiple intensity thresholding algorithm was ... [Opt. Express 17, 4189-4207 (2009)]
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    14. Segmentation of flowing particles using joint spectral and time domain optical coherence tomography

      We propose a modified method of acquisition and analysis of Spectral Optical Coherence Tomography (SOCT) data to provide information about flow velocities in three dimensions. Joint Spectral and Time domain Optical Coherence Tomography (joint STdOCT) enables flow velocity assessment and segmentation ... [Proc. SPIE 7168, 71680C (2009)] published Thu Feb 19, 2009.
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    15. Swept source OCT imaging of human anterior segment at 200 kHz

      Karol Karnowski, Michalina Gora, Bartlomiej Kaluzny et al. We present applicability of the high speed swept-source optical coherence tomography for in vivo imaging of the anterior segment of the human eye. Three dimensional imaging of the cornea with reduced motion artifacts is possible by using swept source with Fourier domain mode locking operating at 200 ... [Proc. SPIE 7163, 716308 (2009)] published Wed Feb 18, 2009.
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    16. Optical Coherence Tomography for Non-Destructive Investigations of Structure of Objects of Art

      Optical Coherence Tomography for Non-Destructive Investigations of Structure of Objects of Art
      In this contribution the Optical Coherence Tomography (OCT), as a novel tool for non-invasive structural imaging of selected objects of cultural heritage, will be reviewed. This technique relies on multispectral interference o f infrared light and therefore is well suited for investigation of transparent and semi-transparent structures. The technique originates from medical imaging and has been present in conservation science since 2004. Until now it has been successfully utilized in imaging of varnishes, glazes and underdrawings of paintings, glazes on porcelain and faience, structure of archaic jades, stained and archeological glass, parchment and recently for revealing the surface details of ...
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    17. Optical coherence tomography in art diagnostics and restoration

      An overview of the technique of optical coherence tomography (OCT) is presented, and a spectral OCT instrument especially designed for art diagnostics is described. The applicability of OCT to the stratigraphy of oil paintings is discussed with emphasis on examination of the artist’s signature. For the first time, OCT tomograms of stained glass are presented and discussed. The utilisation of Spectral OCT in real-time monitoring of varnish ablation is discussed with examples of ablation, melting and evaporation, and exfoliation of the varnish layer provided, for the first time.
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    18. Optical coherence tomography for varnish ablation monitoring

      Optical Coherence Tomography (OCT) is a new, fast-growing technique for non-contact and non-destructive imaging of semi-transparent objects. It has been recently used for diverse applications in art conservation subject - among others it is very well suited for varnish layer imaging and thus for monitoring of varnish removing process, including the laser ablation. In this study we show how to use the OCT technique to obtain the information required for the optimisation of the laser emission parameters like fluency and working regime, with respect to efficiency and safety of the ablation process. We also demonstrate application of the Spectral Optical Coherence ...
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    19. Optical Coherence Tomography for Artwork Diagnostics

      Optical Coherence Tomography for Artwork Diagnostics
      An overview of the optical coherence tomography (OCT) technique is given. Time domain, spectral and sweep source modalities are briefly described, and important physical parameters of the OCT instrument are discussed. Examples of the application of OCT to diagnosis of various art objects such as oil paintings on canvas (imaging of glaze and varnish layers), porcelain, faience, and parchment are presented. Applications to surface profilometry of painting on canvas are also discussed
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    20. Optical Coherence Tomography for Tracking Canvas Deformation

      Optical Coherence Tomography for Tracking Canvas Deformation
      Preliminary results of the application of optical coherence tomography (OCT), in particular in its spectral mode (SOCT), to tracking of deformations in paintings on canvas caused by periodical humidity changes are presented. The setup is able to monitor the position of a chosen point at the surface of a painting with micrometre precision, simultaneously in three dimensions, every 100 seconds. This allows recording of deformations associated with crack formation. For the particular painting model examined, it was shown that the surface moves in-plane towards the corner, and bulges outwards (Z-direction) in response to a rise in humidity. Subsequent to the ...
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    21. Optical Coherence Tomography for Examination of Parchment Degradation

      Optical Coherence Tomography for Examination of Parchment Degradation
      A novel application of Optical Coherence Tomography utilizing infrared light of 830 nm central wavelength for non invasive examination of the structure of parchment, some covered with iron gall ink, is presented. It is shown that both the parchment and the ink applied are sufficiently transparent to light of this wavelength. In the study, Spectral OCT (SOCT) as well as Polarisation Sensitive OCT (PS-OCT) techniques were used to obtain cross-sectional images of samples of parchment based on scattering properties. The second technique was additionally employed to recover the birefringence properties and the optical axis orientations of the sample. It was ...
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    22. Varnish Ablation Control by Optical Coherence Tomography

      Varnish Ablation Control by Optical Coherence Tomography
      Preliminary results of the application of optical coherence tomography (OCT), in particular in its spectral mode (SOCT) to the control of a varnish ablation process, are presented. Examination of the ablation craters made with an Er:YAG laser allows optimization of the laser emission parameters controlling fluence with respect to efficiency and safety of the ablation process. Results of measurements of ablation crater depth as a function of the number of pulses for a given fluence are presented for selected resins. This validates the applicability of SOCT to calibration of ablation conditions for the particular laser-varnish-paint layer combinations, and of ...
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    1-22 of 22
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  2. Topics in the News

    1. (21 articles) Michalina J. Góra
    2. (17 articles) Nicolaus Copernicus University
    3. (10 articles) Maciej Wojtkowski
    4. (9 articles) Piotr Targowski
    5. (8 articles) Andrzej A. Kowalczyk
    6. (7 articles) Maciej Szkulmowski
    7. (4 articles) Massachusetts General Hospital
    8. (4 articles) Bartlomiej J. Kaluzny
    9. (4 articles) Karol Karnowski
    10. (4 articles) Ireneusz Grulkowski
    11. (1 articles) Institute of Applied Physics
    12. (1 articles) Medical University of Vienna
    13. (1 articles) Kyungpook National University
    14. (1 articles) Singapore Eye Research Institute
    15. (1 articles) University of Western Australia
    16. (1 articles) Stefan G. Sacu
    17. (1 articles) Brendan F. Kennedy
    18. (1 articles) Yongyang Huang
    19. (1 articles) Jeehyun Kim
    20. (1 articles) Ursula Schmidt-Erfurth
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    Optical Coherence Tomography for Non-Destructive Investigations of Structure of Objects of Art Optical Coherence Tomography for Tracking Canvas Deformation Optical Coherence Tomography for Examination of Parchment Degradation Comparison of reflectivity maps and outer retinal topography in retinal disease by 3-D Fourier domain optical coherence tomography Anterior segment imaging with Spectral OCT system using a high-speed CMOS camera Ultra high-speed swept source OCT imaging of the anterior segment of human eye at 200 kHz with adjustable imaging range Corneal topography with high-speed swept source OCT in clinical examination Postdoctoral Research Fellowship in Biomedical Optics at CNRS/Strasbourg University Full-range space-division multiplexing optical coherence tomography angiography Measuring 3D Optic Nerve Head Deformations using Digital Volume Correlation of in vivo Optical Coherence Tomography Data (Thesis) Optical coherence tomography for characterization of nanocomposite materials (Thesis) In Vivo Corneal Microstructural Changes in Herpetic Stromal Keratitis: A Spectral-Domain Optical Coherence Tomography Analysis