1. Articles from Evald H. Christiansen

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    1. Serial Assessment of Tissue Precursors and Progression of Coronary Calcification Analyzed by Fusion of IVUS and OCT

      Serial Assessment of Tissue Precursors and Progression of Coronary Calcification Analyzed by Fusion of IVUS and OCT

      Objectives The aim of this study was to assess calcium growth with fused grayscale intravascular ultrasound (IVUS), IVUS–virtual histology, and optical coherence tomography (OCT) from baseline to 5-year follow-up in patients treated with bioresorbable vascular scaffolds. Background IVUS and OCT have individual strengths in assessing plaque composition and volume. Fusion of images obtained using these methods could potentially aid in coronary plaque assessment. Methods Anatomic landmarks and endoluminal radiopaque markers were used to fuse OCT and IVUS images and match baseline and follow-up. Results Seventy-two IVUS–virtual histology and OCT paired matched cross-sectional in- and out-scaffold segments were fused ...

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    2. Impact of Side Branch Modeling on Computation of Endothelial Shear Stress in Coronary Artery Disease Coronary Tree Reconstruction by Fusion of 3D Angiography and OCT

      Impact of Side Branch Modeling on Computation of Endothelial Shear Stress in Coronary Artery Disease Coronary Tree Reconstruction by Fusion of 3D Angiography and OCT

      Background Computational fluid dynamics allow virtual evaluation of coronary physiology and shear stress (SS). Most studies hitherto assumed the vessel as a single conduit without accounting for the flow through side branches. Objectives This study sought to develop a new approach to reconstruct coronary geometry that also computes outgoing flow through side branches in hemodynamic and biomechanical calculations, using fusion of optical coherence tomography (OCT) and 3-dimensional (3D) angiography. Methods Twenty-one patients enrolled in the DOCTOR (Does Optical Coherence Tomography Optimize Revascularization) fusion study underwent OCT and 3D-angiography of the target vessel (9 left anterior descending, 2 left circumflex, 10 ...

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    3. Left Main Coronary Artery Lesions and Optical Coherence Tomography

      Left Main Coronary Artery Lesions and Optical Coherence Tomography

      Optimal treatment of left main coronary artery (LMCA) lesions requires a highly tailored approach that incorporates patient comorbidities, clinical presentation, the extent of coronary artery disease (CAD), lesion characteristics and local expertise. 1,2 Coronary artery bypass grafting (CABG) is the treatment for LMCA lesions that has the highest evidence level in guideline recommendations. 2,3 However, the evidence for percutaneous coronary intervention (PCI) has increased in recent years and is now class IIa for ostial and trunk LMCA lesions and IIb for distal LMCA bifurcation treatment in stable patients suited for PCI. 2,3 However, these lesion-specific recommendations cannot ...

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      Mentions: Abbott
    4. First In Vivo Demonstration of Coronary Edema in Culprit Lesion of Patient With Acute Coronary Syndrome by Cardiovascular Magnetic Resonance

      First In Vivo Demonstration of Coronary Edema in Culprit Lesion of Patient With Acute Coronary Syndrome by Cardiovascular Magnetic Resonance
      Atherosclerosis is a chronic, progressive, inflammatory disease causing multiple lesions in the intima of large and medium-sized arteries. 1 A minority of atherosclerotic lesions referred to as vulnerable plaques (VPs) may suddenly precipitate thrombosis, leading to life-threatening events such as acute myocardial infarction and ischemic stroke. The most common VP is the rupture-prone type, also known as thin-cap fibroatheromas, which are characterized by a large necrotic core with a thin and inflamed fibrous cap, outward remodeling mitigating luminal obstruction, neovascularization, plaque hemorrhage, adventitial inflammation, and a “spotty” pattern of calcifications. 2 Among these features, inflammation and angiogenesis are believed to ...
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    1-6 of 6
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  2. Topics in the News

    1. (4 articles) Aarhus University
    2. (3 articles) Leiden University
    3. (2 articles) Abbott
    4. (1 articles) Academic Medical Center at the University of Amsterdam
    5. (1 articles) Capital Medical University
    6. (1 articles) Shanghai Jiao Tong University
    7. (1 articles) University of Bern
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    First In Vivo Demonstration of Coronary Edema in Culprit Lesion of Patient With Acute Coronary Syndrome by Cardiovascular Magnetic Resonance Use of three-dimensional optical coherence tomography to verify correct wire position in a jailed side branch after main vessel stent implantation First Presentation of 3-Dimensional Reconstruction and Centerline-Guided Assessment of Coronary Bifurcation by Fusion of X-Ray Angiography and Optical Coherence Tomography Left Main Coronary Artery Lesions and Optical Coherence Tomography Impact of Side Branch Modeling on Computation of Endothelial Shear Stress in Coronary Artery Disease Coronary Tree Reconstruction by Fusion of 3D Angiography and OCT Serial Assessment of Tissue Precursors and Progression of Coronary Calcification Analyzed by Fusion of IVUS and OCT Structural abnormalities associated with glaucoma using swept-source optical coherence tomography in patients with systemic sclerosis Clinical presentation does not affect acute mechanical performance of the Novolimus-eluting bioresorbable vascular scaffold as assessed by optical coherence tomography Evaluating optical coherence tomography (OCT) findings as potential biomarkers in central nervous system (CNS) lymphoma with or without ocular involvement Polarization sensitive optical coherence tomography with single input for imaging depth-resolved collagen organizations Etanercept Therapy for Nails Psoriasis Monitoring With Noninvasive Imaging The Use of Optical Coherence Tomography to Asscess Water Transport Through The Urothelium of The Porcine Bladder