1. Articles from Rosa Dolz-Marco

    1-17 of 17
    1. Clinical utility of morphofunctional correlation of microperimetry and optical coherence tomography

      Clinical utility of morphofunctional correlation of microperimetry and optical coherence tomography

      Purpose: To demonstrate the clinical and research value of a simplified technique enabling alignment of functional microperimetry data with retinal structure imaged by eye-tracked optical coherence tomography (OCT) in eyes with macular disease. Methods: Normal and diseased eyes underwent sequential Spectralis OCT macular raster scans and Macular Integrity Assessment (MAIA) microperimetry using both standard central 10° analysis and custom scan patterns. The microperimetry data were imported into Spectralis research software which was automatically registered to the scanning laser ophthalmoscopy near-infrared reflectance image obtained during OCT acquisition. The OCT B-scans were directly correlated to the microperimetry data so that retina sensitivity ...

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    2. Directional Changes In Tissue Reflectivity May Influence Flow Detection On Optical Coherence Tomography Angiography

      Directional Changes In Tissue Reflectivity May Influence Flow Detection On Optical Coherence Tomography Angiography

      Purpose: To determine if directional or anatomical changes in tissue reflectivity of Henle fiber layer (HFL) may influence flow detection on optical coherence tomography angiography ( OCT-A ). Methods: Cross-sectional analysis of consecutive cases undergoing OCT-A . Directional changes in visualization of HFL were either produced manually by moving the beam entrance within the pupil or observed occurring naturally because of tilting of the OCT line-scan within a myopic staphyloma. Areas of enhanced HFL visualization were identified on cross-sectional and en face structural OCT scans. Visualization of OCT-A flow within the superficial and the deep capillary plexuses were compared in areas with and ...

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      Mentions: K. Bailey Freund
    3. INNER CHOROIDAL FLOW SIGNAL ATTENUATION IN PACHYCHOROID DISEASE: Optical Coherence Tomography Angiography

      INNER CHOROIDAL FLOW SIGNAL ATTENUATION IN PACHYCHOROID DISEASE: Optical Coherence Tomography Angiography

      Purpose: To study zones of reduced inner choroidal flow signal, foci of reduced inner choroidal thickness, and pathologically dilated Haller layer vessels (pachyvessels) in eyes with pachychoroid disease using optical coherence tomography (OCT) and OCT angiography. Methods: Patients with treatment-naive pachychoroid disease were recruited. All patients prospectively underwent swept-source OCT and OCT angiography. Zones of reduced choriocapillaris flow were labeled and enumerated. Areas where reduced flow signal was attributable to masking/artifacts were excluded. Regions of inner choroidal thinning were identified on structural OCT and labeled. Overlap between reduced choriocapillaris flow and structural inner choroidal attenuation was quantified using Jaccard ...

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      Mentions: K. Bailey Freund
    4. Optical coherence tomography angiography: a review of current and future clinical applications

      Optical coherence tomography angiography: a review of current and future clinical applications

      Optical coherence tomography angiography is a non-invasive imaging technique that now allows for simultaneous in vivo imaging of the morphology as well as the vasculature in the eye. In this review, we provide an update on the existing clinical applications of optical coherence tomography angiography technology from the anterior to posterior segment of the eye. We also discuss the limitations of optical coherence tomography angiography technology, as well as the caveats to the interpretation of images. As current optical coherence tomography angiography systems are optimized for the retina, most studies have focused on interpreting images from conditions such as age ...

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    5. DIRECTIONAL CHANGES IN TISSUE REFLECTIVITY MAY INFLUENCE FLOW DETECTION ON OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      DIRECTIONAL CHANGES IN TISSUE REFLECTIVITY MAY INFLUENCE FLOW DETECTION ON OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      Purpose: To determine if directional or anatomical changes in tissue reflectivity of Henle fiber layer (HFL) may influence flow detection on optical coherence tomography angiography (OCT-A). Methods: Cross-sectional analysis of consecutive cases undergoing OCT-A. Directional changes in visualization of HFL were either produced manually by moving the beam entrance within the pupil or observed occurring naturally because of tilting of the OCT line-scan within a myopic staphyloma. Areas of enhanced HFL visualization were identified on cross-sectional and en face structural OCT scans. Visualization of OCT-A flow within the superficial and the deep capillary plexuses were compared in areas with and ...

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      Mentions: K. Bailey Freund
    6. Prevalence of Different Optical Coherence Tomography Findings in a Spanish Cohort With High Myopia

      Prevalence of Different Optical Coherence Tomography Findings in a Spanish Cohort With High Myopia

      Purpose: To evaluate the prevalence of different optical coherence tomography (OCT) findings in European patients with high myopia. Methods: Cross-sectional study conducted in the Macula Unit of the University and Polytechnic Hospital La Fe (Valencia, Spain). A total of 134 myopic eyes of 69 patients (16 males and 53 females) were included. All patients underwent a spectral domain OCT examination at least once. The presence of tractional and atrophic myopic maculopathy and choroidal neovascularization (CNV) was evaluated through OCT scans. Results: The prevalence of tractional myopic maculopathy was found in 53.7% of the eyes. Within this group, 9.7 ...

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    7. OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY SHOWS INNER CHOROIDAL ISCHEMIA IN ACUTE POSTERIOR MULTIFOCAL PLACOID PIGMENT EPITHELIOPATHY

      OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY SHOWS INNER CHOROIDAL ISCHEMIA IN ACUTE POSTERIOR MULTIFOCAL PLACOID PIGMENT EPITHELIOPATHY

      Purpose: To describe multimodal imaging findings of an evolving case of acute posterior multifocal placoid pigment epitheliopathy occurring in a young healthy male. Methods: Case report of a patient with acute posterior multifocal placoid pigment epitheliopathy including comprehensive systemic and ocular examinations. Ultra-widefield autofluorescence, fluorescein angiography, indocyanine green angiography, and serial optical coherence tomography angiography were performed. Results: A 34-year-old male presented with acute vision loss in his left eye for 2 weeks. His best-corrected visual acuity was 20/20 in his right eye and 20/200 in his left eye. Dilated funduscopic examination revealed multiple creamy white deep retinal ...

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      Mentions: K. Bailey Freund
    8. Fractal Dimensional Analysis of Optical Coherence Tomography Angiography in Eyes With Diabetic Retinopathy

      Fractal Dimensional Analysis of Optical Coherence Tomography Angiography in Eyes With Diabetic Retinopathy

      Purpose : We used fractal dimensional analysis to analyze retinal vascular disease burden in eyes with diabetic retinopathy using spectral-domain optical coherence tomography angiography (OCTA). Methods : A retrospective study was performed of 13 eyes with diabetic retinopathy without diabetic macular edema and 56 control eyes. Optical coherence tomography angiography images were acquired using the RTVue XR Avanti. Automated segmentation was obtained through the superficial and deep capillary plexuses for each eye. Grayscale OCTA images were standardized and binarized using ImageJ. Fractal box-counting analyses were performed using Fractalyse. Fractal dimensions (FD) as well as software-generated vascular density analyses of the superficial and ...

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    9. Optical Coherence Tomography Angiography in Fovea Plana

      Optical Coherence Tomography Angiography in Fovea Plana

      Fovea plana is characterized by the anatomical absence of the foveal pit in eyes with normal visual function. The authors have analyzed three cases of idiopathic fovea plana with optical coherence tomography angiography (OCTA). As previously reported, the authors found the absence of a foveal avascular zone in all cases with OCTA; however, a preserved fusion of both the superficial and the deep capillary plexuses was found around the foveal center. This novel observation cannot be detected with conventional dye-based angiography, in which the deep capillary plexus is not visualized.

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    10. Automated macular choroidal thickness measurement by swept-source optical coherence tomography in pseudoxanthoma elasticum

      Automated macular choroidal thickness measurement by swept-source optical coherence tomography in pseudoxanthoma elasticum

      Introduction Pseudoxanthoma elasticum (PXE) typically involves elastic fibers in blood vessels and Bruch membrane. Our purpose was to analyze retinal and choroidal macular thickness in patients with angioid streaks due PXE compared with a control group. Methods Best-corrected visual acuity (BCVA), axial length (AL), and macular swept-source optical coherence tomography were obtained. Automated segmentations of the retina and the choroid were used to obtain the corresponding thickness values. An age, gender and AL matched control group was used to compare the thickness values. Results Twelve eyes of 6 patients were included. The mean BCVA was 0.68 ± 0.29 versus ...

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    11. Posterior Scleral Bowing With Choroidal Nevus on Enhanced-Depth Imaging Optical Coherence Tomography

      Posterior Scleral Bowing With Choroidal Nevus on Enhanced-Depth Imaging Optical Coherence Tomography

      Importance Recognition of posterior scleral bowing with choroidal nevus is essential to avoid an underestimation of tumor thickness. Objective To describe a particular observation of posterior scleral bowing associated with choroidal nevus on enhanced-depth imaging (EDI) optical coherence tomography (OCT). Design, Setting, and Participants Retrospective observational case series at a referral center involving 17 eyes of 17 patients. Patients were seen from June 2013 to July 2014, with all data collected and analyzed from June 2014 to July 2014. Interventions Retrospective medical record review and multimodal imaging including fundus photography, autofluorescence, infrared reflectance, ultrasonography, and EDI-OCT. Main Outcomes and Measures ...

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    12. Macular retinal and choroidal thickness in unilateral relentless placoid chorioretinitis analyzed by swept-source optical coherence tomography

      Macular retinal and choroidal thickness in unilateral relentless placoid chorioretinitis analyzed by swept-source optical coherence tomography

      Background The purpose of this study is to evaluate the retinal and choroidal thickness of the macular region in patients with unilateral relentless placoid chorioretinitis (RPC) and macular involvement. Patients diagnosed with RPC affecting only one eye underwent a comprehensive ophthalmologic examination including best-corrected visual acuity (BCVA), axial length (AL) measurement, slit-lamp examination, and color fundus and autofluorescence photography. The macular region was scanned by swept-source optical coherence tomography in the 1,050-nm wavelength. Automated segmentations of the retina and the choroid were used to obtain the corresponding thickness values. Results A total number of three patients (two men and ...

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    13. Treatment decisions in diabetic macular edema based on optical coherence tomography retinal thickness map: LET classification

      Treatment decisions in diabetic macular edema based on optical coherence tomography retinal thickness map: LET classification

      Dear Editor, The approval of intravitreal injections of ranibizumab for the management of diabetic macular edema (DME) has induced a dramatical shift in the therapeutic approach of this entity, as the major clinical trials have proven the significant benefit of this treatment for patients with center-involving DME [ 1 – 3 ]. As a consequence, the classification of DME needs to be updated so that a useful correlation between grading and therapeutic indication could be assumed. Nowadays, the key feature of DME is the involvement or sparing of the fovea. Whenever DME involves the fovea, a clear indication for treatment with ranibizumab seems ...

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    14. Macular laser photocoagulation guided by spectral-domain optical coherence tomography versus fluorescein angiography for diabetic macular edema

      Macular laser photocoagulation guided by spectral-domain optical coherence tomography versus fluorescein angiography for diabetic macular edema

      Background: The aim of this study was to compare the efficacy of spectral-domain optical coherence tomography (SD-OCT) and fluorescein angiography (FA) in the guidance of macular laser photocoagulation for diabetic macular edema.Methods: This was a prospective interventional clinical comparative pilot study. Forty eyes from 24 consecutive patients with diabetic macular edema were allocated to receive laser photocoagulation guided by SD-OCT or FA. Best-corrected visual acuity (BCVA), central macular thickness, and retinal volume were assessed at baseline and two months after treatment.Results: Subjects treated using FA-guided laser improved BCVA from the logarithm of the minimum angle of resolution (logMAR ...

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    1-17 of 17
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    1. (7 articles) Roberto Gallego-Pinazo
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    Macular laser photocoagulation guided by spectral-domain optical coherence tomography versus fluorescein angiography for diabetic macular edema Need to consensus for novel findings by optical coherence tomography in patients with age-related macular degeneration Treatment decisions in diabetic macular edema based on optical coherence tomography retinal thickness map: LET classification Focal Inferotemporal Scleral Bulge With Choroidal Thinning: A New Observation on High-Penetration Optical Coherence Tomography Macular retinal and choroidal thickness in unilateral relentless placoid chorioretinitis analyzed by swept-source optical coherence tomography Posterior Scleral Bowing With Choroidal Nevus on Enhanced-Depth Imaging Optical Coherence Tomography Automated macular choroidal thickness measurement by swept-source optical coherence tomography in pseudoxanthoma elasticum Optical Coherence Tomography Angiography in Fovea Plana Fractal Dimensional Analysis of Optical Coherence Tomography Angiography in Eyes With Diabetic Retinopathy Prevalence of Different Optical Coherence Tomography Findings in a Spanish Cohort With High Myopia Both speckle reduction and contrast enhancement for optical coherence tomography via sequential optimization in the logarithmic domain based on a refined Retinex model OCT parameters of the optic nerve head and the retina as surrogate markers of brain volume in a normal population, a pilot study