1. Articles from Roberto Gallego-Pinazo

    1-12 of 12
    1. Correlation analysis of fundus autofluorescence, spectral domain optical coherence tomography, and visual function in patients with diabetic macular oedema treated with intravitreal ziv-aflibercept

      Correlation analysis of fundus autofluorescence, spectral domain optical coherence tomography, and visual function in patients with diabetic macular oedema treated with intravitreal ziv-aflibercept

      Purpose: The aim of this study was to evaluate the correlations between fundus autofluorescence and morphologic parameters as well as visual function in patients with diabetic macular oedema treated with intravitreal ziv-aflibercept. Methods: A total of 34 eyes of 20 patients with untreated diabetic macular oedema received an intravitreal injection of ziv-aflibercept at baseline, and 1 and 2 months later. The baseline, 1-month, and two-month best corrected visual acuity determination, contrast sensitivity, spectral domain optical coherence tomography, mean central macular thickness, mean macular cube volume, mean macular cube average thickness, and fundus autofluorescence (decreased, normal, or increased; and single or ...

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    2. Optical Coherence Tomography Characterization of Macular Changes Secondary to Arteriovenous Fistula

      Optical Coherence Tomography Characterization of Macular Changes Secondary to Arteriovenous Fistula

      Arteriovenous fistulas (AVFs) are abnormal shunts between the arterial and venous vascular systems. These usually produce ocular pain, increased intraocular pressure (IOP), and diplopia. Less frequently, they may cause retinal changes with visual impairment. Our purpose is to illustrate different retinal manifestations of AVF. We report the multimodal imaging study of three cases with retinal changes due to AVF, showing neurosensory retinal detachment, macular oedema, and macular ischemia. In conclusion, AVF may appear with different ophthalmic alterations. While usually increased IOP and diplopia are our main concerns, retinal study is mandatory, since a myriad of morphologic abnormalities might be present.

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    3. Prevalence of Different Optical Coherence Tomography Findings in a Spanish Cohort With High Myopia

      Prevalence of Different Optical Coherence Tomography Findings in a Spanish Cohort With High Myopia

      Purpose: To evaluate the prevalence of different optical coherence tomography (OCT) findings in European patients with high myopia. Methods: Cross-sectional study conducted in the Macula Unit of the University and Polytechnic Hospital La Fe (Valencia, Spain). A total of 134 myopic eyes of 69 patients (16 males and 53 females) were included. All patients underwent a spectral domain OCT examination at least once. The presence of tractional and atrophic myopic maculopathy and choroidal neovascularization (CNV) was evaluated through OCT scans. Results: The prevalence of tractional myopic maculopathy was found in 53.7% of the eyes. Within this group, 9.7 ...

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    4. Automated macular choroidal thickness measurement by swept-source optical coherence tomography in pseudoxanthoma elasticum

      Automated macular choroidal thickness measurement by swept-source optical coherence tomography in pseudoxanthoma elasticum

      Introduction Pseudoxanthoma elasticum (PXE) typically involves elastic fibers in blood vessels and Bruch membrane. Our purpose was to analyze retinal and choroidal macular thickness in patients with angioid streaks due PXE compared with a control group. Methods Best-corrected visual acuity (BCVA), axial length (AL), and macular swept-source optical coherence tomography were obtained. Automated segmentations of the retina and the choroid were used to obtain the corresponding thickness values. An age, gender and AL matched control group was used to compare the thickness values. Results Twelve eyes of 6 patients were included. The mean BCVA was 0.68 ± 0.29 versus ...

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    5. Macular retinal and choroidal thickness in unilateral relentless placoid chorioretinitis analyzed by swept-source optical coherence tomography

      Macular retinal and choroidal thickness in unilateral relentless placoid chorioretinitis analyzed by swept-source optical coherence tomography

      Background The purpose of this study is to evaluate the retinal and choroidal thickness of the macular region in patients with unilateral relentless placoid chorioretinitis (RPC) and macular involvement. Patients diagnosed with RPC affecting only one eye underwent a comprehensive ophthalmologic examination including best-corrected visual acuity (BCVA), axial length (AL) measurement, slit-lamp examination, and color fundus and autofluorescence photography. The macular region was scanned by swept-source optical coherence tomography in the 1,050-nm wavelength. Automated segmentations of the retina and the choroid were used to obtain the corresponding thickness values. Results A total number of three patients (two men and ...

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    6. Treatment decisions in diabetic macular edema based on optical coherence tomography retinal thickness map: LET classification

      Treatment decisions in diabetic macular edema based on optical coherence tomography retinal thickness map: LET classification

      Dear Editor, The approval of intravitreal injections of ranibizumab for the management of diabetic macular edema (DME) has induced a dramatical shift in the therapeutic approach of this entity, as the major clinical trials have proven the significant benefit of this treatment for patients with center-involving DME [ 1 – 3 ]. As a consequence, the classification of DME needs to be updated so that a useful correlation between grading and therapeutic indication could be assumed. Nowadays, the key feature of DME is the involvement or sparing of the fovea. Whenever DME involves the fovea, a clear indication for treatment with ranibizumab seems ...

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    7. Spectral-Domain Optical Coherence Tomography and Fundus Autofluorescence Findings in A Case of Laser Pointer-Induced Maculopathy

      Spectral-Domain Optical Coherence Tomography and Fundus Autofluorescence Findings in A Case of Laser Pointer-Induced Maculopathy

      Purpose: To describe the spectral-domain optical coherence tomography and fundus autofluorescence findings in a case of laser pointer-induced maculopathy. Methods: Observational case report of a patient with bilateral decreased visual acuity after exposure to a handheld green laser pointer. Results: A 15-year-old boy presented with decreased vision after exposure to a green laser pointer. Fundoscopy revealed gray and yellowish round spots in the foveal area of both eyes. Fundus autofluorescence imaging revealed subtle changes of the normal background macular autofluorescence of the right eye, with hyperautofluorescence dots in the fovea of the left eye. Spectral-domain optical coherence tomography showed a ...

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    8. Recognition of Henle's Fiber Layer on OCT Images

      Recognition of Henle's Fiber Layer on OCT Images

      Monés et al made an important observation about how important is to recognize the normal anatomy of the Henle's fiber layer in the optical coherence tomography images (OCT). Spectral-domain (SD) OCT offers the possibility of evaluating retinal architecture at near-histologic levels of resolution. However, clinicians should be aware that optical variations induced by examination conditions might alter the reflectivity of the retinal layers. This consideration is particularly true when imaging the outer plexiform layer (OPL) within the central macula.

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    9. Optical Coherence Tomographic Imaging of Sub-Retinal Pigment Epithelium Lipid

      Optical Coherence Tomographic Imaging of Sub-Retinal Pigment Epithelium Lipid

      Objective To describe an optical coherence tomographic finding of layered hyperreflective bands beneath the retinal pigment epithelium (RPE), the so-called onion sign believed to represent lipid within a vascularized pigment epithelial detachment. Methods This retrospective observational case series involved reviewing clinical histories of patients with the onion sign. Imaging studies analyzed included spectral-domain optical coherence tomography, color and red-free photographs, near infrared reflectance, fundus autofluorescence, and blue-light fundus autofluorescence. Results A total of 22 eyes of 20 patients with sub-RPE hyperreflective bands were identified. There were 15 women and 5 men with a mean patient age of 76 years (range ...

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    10. Macular laser photocoagulation guided by spectral-domain optical coherence tomography versus fluorescein angiography for diabetic macular edema

      Macular laser photocoagulation guided by spectral-domain optical coherence tomography versus fluorescein angiography for diabetic macular edema

      Background: The aim of this study was to compare the efficacy of spectral-domain optical coherence tomography (SD-OCT) and fluorescein angiography (FA) in the guidance of macular laser photocoagulation for diabetic macular edema.Methods: This was a prospective interventional clinical comparative pilot study. Forty eyes from 24 consecutive patients with diabetic macular edema were allocated to receive laser photocoagulation guided by SD-OCT or FA. Best-corrected visual acuity (BCVA), central macular thickness, and retinal volume were assessed at baseline and two months after treatment.Results: Subjects treated using FA-guided laser improved BCVA from the logarithm of the minimum angle of resolution (logMAR ...

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    1-12 of 12
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  2. Topics in the News

    1. (10 articles) Roberto Gallego-Pinazo
    2. (4 articles) University of Valencia
    3. (3 articles) LuEsther T. Mertz Retinal Research Center
    4. (3 articles) K. Bailey Freund
    5. (1 articles) Thomas Jefferson University
    6. (1 articles) Carol L. Shields
    7. (1 articles) Michel Pâques
    8. (1 articles) Jerome Sherman
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    Macular laser photocoagulation guided by spectral-domain optical coherence tomography versus fluorescein angiography for diabetic macular edema Optical Coherence Tomographic Imaging of Sub-Retinal Pigment Epithelium Lipid Need to consensus for novel findings by optical coherence tomography in patients with age-related macular degeneration Recognition of Henle's Fiber Layer on OCT Images Spectral-Domain Optical Coherence Tomography and Fundus Autofluorescence Findings in A Case of Laser Pointer-Induced Maculopathy Treatment decisions in diabetic macular edema based on optical coherence tomography retinal thickness map: LET classification Focal Inferotemporal Scleral Bulge With Choroidal Thinning: A New Observation on High-Penetration Optical Coherence Tomography Macular retinal and choroidal thickness in unilateral relentless placoid chorioretinitis analyzed by swept-source optical coherence tomography Automated macular choroidal thickness measurement by swept-source optical coherence tomography in pseudoxanthoma elasticum Prevalence of Different Optical Coherence Tomography Findings in a Spanish Cohort With High Myopia Both speckle reduction and contrast enhancement for optical coherence tomography via sequential optimization in the logarithmic domain based on a refined Retinex model OCT parameters of the optic nerve head and the retina as surrogate markers of brain volume in a normal population, a pilot study