1. Articles from Hans-Martin Helb

    1-4 of 4
    1. High-resolution optical coherence tomography of subpigment epithelial structures in patients with pigment epithelium detachment secondary to age-related macular degeneration

      High-resolution optical coherence tomography of subpigment epithelial structures in patients with pigment epithelium detachment secondary to age-related macular degeneration

      Background The pathophysiology of pigment epithelial detachment (PED) secondary to age-related macular degeneration (AMD) is as yet incompletely understood and treatment remains challenging. Spectral domain optical coherence tomography (SD-OCT) allows for improved morphological characterisation of the space underneath the retinal pigment epithelium (RPE). Objective To investigate eyes with PED for structures underneath the detached RPE cell layer. Methods In a retrospective observational case study, SD-OCT scans of AMD-related PEDs were assessed for the presence of distinctive morphological features in the space between the detached RPE and inner Bruch's membrane. Results Structures present in the space between the detached RPE ...

      Read Full Article
    2. Clinical evaluation of simultaneous confocal scanning laser ophthalmoscopy imaging combined with high-resolution, spectral-domain optical coherence tomography

      Purpose: To evaluate the clinical relevance of a new diagnostic modality, simultaneous confocal scanning laser ophthalmoscopy (cSLO) and high-speed, high-resolution, spectral-domain optical coherence tomography (OCT), for the visualization of macular pathologies. Methods: OCT images and simultaneous recording of fluorescein angiography, indocyanine green (ICG) angiography, infrared, and blue reflectance ('red-free') or fundus autofluorecence (FAF) images were obtained with a novel imaging device (Spectralis HRA + OCT; Heidelberg Engineering, Heidelberg, Germany). An optically pumped solid-state laser generated the excitation wavelength (488 nm) required for blue reflectance, FAF and fluorescein angiography images. For ICG angiography and infrared imaging, diode laser sources at 790 and ...
      Read Full Article
    3. Correlation of Lines of Increased Autofluorescence in Macular Dystrophy and Pigmented Paravenous Retinochoroidal Atrophy by Optical Coherence Tomography

      Discrete lines of increased fundus autofluorescence (FAF) have recently been described in various retinal dystrophies.1-2 It has been shown that these lines demarcate areas with impaired retinal sensitivity from those without and may constrict or expand in different retinal dystrophies over time.1-2 Morphological changes corresponding to lines of increased FAF have not been described yet. Likewise, the mechanism underlying the abnormal accumulation of lipofuscin and increased FAF is unknown. In retinitis pigmentosa, abnormally increased FAF commonly forms a parafoveal ring or annulus. Recent optical coherence tomography (OCT) findings suggest that the band that represents the interface of the ...
      Read Full Article
    4. Multimodal Fundus Imaging in Foveal Hypoplasia: Combined Scanning Laser Ophthalmoscope Imaging and Spectral-Domain Optical Coherence Tomography

      Foveal hypoplasia is a rare disease that mostly occurs in association with other systemic or ocular diseases, such as albinism or aniridia. Diagnosis can be challenging, especially if foveal hypoplasia is an isolated finding. In recent years, optical coherence tomography (OCT) has been described as a useful tool to confirm the suspected diagnosis.1-3 However, the common asso ciation of nystagmus with foveal hypoplasia may generate artifacts in OCT scans and may lead to off-center scans and therefore unreliable results.1 We examined 2 patients with foveal hypoplasia by using a simultaneous imaging device that combines a confocal scanning laser ...
      Read Full Article
    1-4 of 4
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Topics in the News

    1. (4 articles) University of Bonn
    2. (3 articles) Heidelberg Engineering
    3. (1 articles) Soochow University
    4. (1 articles) Topcon Medical Systems
    5. (1 articles) CSO
    6. (1 articles) Movu
  3. Popular Articles

  4. Picture Gallery

    High-resolution optical coherence tomography of subpigment epithelial structures in patients with pigment epithelium detachment secondary to age-related macular degeneration Deep learning models comparison for tissue classification using optical coherence tomography images: toward smart laser osteotomy Optical coherence tomography angiography features of macular neovascularization in wet age-related macular degeneration: A cross-sectional study Automatic focus method using interference fringes magnitudes in retinal optical coherence tomography Improved U-Net for Plaque Segmentation of Intracoronary Optical Coherence Tomography Images The Precision of a New Anterior Segment Optical Coherence Tomographer and Its Comparison With a Swept-Source OCT-Based Optical Biometer in Patients With Cataract A preliminary study of shaker-based optical coherence elastography for assessment of gingival elasticity MultiSDGAN: translation of OCT images to superresolved segmentation labels using multi-discriminators in multi-stages Association between apolipoprotein B/A1 ratio and coronary plaque vulnerability in patients with atherosclerotic cardiovascular disease: an intravascular optical coherence tomography study Prospective evaluation of optical coherence tomography for disease detection in the Casey mobile eye clinic Optical coherence tomography monitoring and diagnosing retinal changes in multiple sclerosis Deep learning-based signal-independent assessment of macular avascular area on 6×6 mm optical coherence tomography angiogram in diabetic retinopathy: a comparison to instrument-embedded software