1. Articles from Hans-Martin Helb

    1-4 of 4
    1. High-resolution optical coherence tomography of subpigment epithelial structures in patients with pigment epithelium detachment secondary to age-related macular degeneration

      High-resolution optical coherence tomography of subpigment epithelial structures in patients with pigment epithelium detachment secondary to age-related macular degeneration

      Background The pathophysiology of pigment epithelial detachment (PED) secondary to age-related macular degeneration (AMD) is as yet incompletely understood and treatment remains challenging. Spectral domain optical coherence tomography (SD-OCT) allows for improved morphological characterisation of the space underneath the retinal pigment epithelium (RPE). Objective To investigate eyes with PED for structures underneath the detached RPE cell layer. Methods In a retrospective observational case study, SD-OCT scans of AMD-related PEDs were assessed for the presence of distinctive morphological features in the space between the detached RPE and inner Bruch's membrane. Results Structures present in the space between the detached RPE ...

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    2. Clinical evaluation of simultaneous confocal scanning laser ophthalmoscopy imaging combined with high-resolution, spectral-domain optical coherence tomography

      Purpose: To evaluate the clinical relevance of a new diagnostic modality, simultaneous confocal scanning laser ophthalmoscopy (cSLO) and high-speed, high-resolution, spectral-domain optical coherence tomography (OCT), for the visualization of macular pathologies. Methods: OCT images and simultaneous recording of fluorescein angiography, indocyanine green (ICG) angiography, infrared, and blue reflectance ('red-free') or fundus autofluorecence (FAF) images were obtained with a novel imaging device (Spectralis HRA + OCT; Heidelberg Engineering, Heidelberg, Germany). An optically pumped solid-state laser generated the excitation wavelength (488 nm) required for blue reflectance, FAF and fluorescein angiography images. For ICG angiography and infrared imaging, diode laser sources at 790 and ...
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    3. Correlation of Lines of Increased Autofluorescence in Macular Dystrophy and Pigmented Paravenous Retinochoroidal Atrophy by Optical Coherence Tomography

      Discrete lines of increased fundus autofluorescence (FAF) have recently been described in various retinal dystrophies.1-2 It has been shown that these lines demarcate areas with impaired retinal sensitivity from those without and may constrict or expand in different retinal dystrophies over time.1-2 Morphological changes corresponding to lines of increased FAF have not been described yet. Likewise, the mechanism underlying the abnormal accumulation of lipofuscin and increased FAF is unknown. In retinitis pigmentosa, abnormally increased FAF commonly forms a parafoveal ring or annulus. Recent optical coherence tomography (OCT) findings suggest that the band that represents the interface of the ...
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    4. Multimodal Fundus Imaging in Foveal Hypoplasia: Combined Scanning Laser Ophthalmoscope Imaging and Spectral-Domain Optical Coherence Tomography

      Foveal hypoplasia is a rare disease that mostly occurs in association with other systemic or ocular diseases, such as albinism or aniridia. Diagnosis can be challenging, especially if foveal hypoplasia is an isolated finding. In recent years, optical coherence tomography (OCT) has been described as a useful tool to confirm the suspected diagnosis.1-3 However, the common asso ciation of nystagmus with foveal hypoplasia may generate artifacts in OCT scans and may lead to off-center scans and therefore unreliable results.1 We examined 2 patients with foveal hypoplasia by using a simultaneous imaging device that combines a confocal scanning laser ...
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    1-4 of 4
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  2. Topics in the News

    1. (4 articles) University of Bonn
    2. (4 articles) Frank G. Holz
    3. (4 articles) Peter Charbel Issa
    4. (3 articles) Hendrik P. N. Scholl
    5. (3 articles) Heidelberg Engineering
    6. (2 articles) Steffen Schmitz-Valckenberg
    7. (1 articles) Tufts University
    8. (1 articles) UCLA
    9. (1 articles) Massachusetts General Hospital
    10. (1 articles) Capital Medical University
    11. (1 articles) University of Auckland
    12. (1 articles) Frederique Vanholsbeeck
    13. (1 articles) Francesco Bandello
    14. (1 articles) Yoshiyasu Minami
    15. (1 articles) Hang Lee
    16. (1 articles) Carl Zeiss Meditec
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    High-resolution optical coherence tomography of subpigment epithelial structures in patients with pigment epithelium detachment secondary to age-related macular degeneration Predictors for Rapid Progression of Coronary Calcification: An Optical Coherence Tomography Study Macular neovascularization in AMD, CSC and best vitelliform macular dystrophy: quantitative OCTA detects distinct clinical entities Effects of the Gaze Fixation Position on AS-OCT Measurements of the Limbus and Extraocular Muscle Insertion Site Distance Anterior Segment Optical Coherence Tomography in Locating the Insertion of Horizontal Extraocular Muscles After Strabismus Surgery Optical coherence tomography-guided management of underexpanded stent in calcified coronary lesion OCT-angiography for diagnosis and response to treatment of subretinal neovascularization secondary to idiopathic macular telangiectasia type 2 Macular edema after rhegmatogenous retinal detachment repair: risk factors, OCT analysis, and treatment responses Towards real time assessment of intramuscular fat content in meat using optical fiber-based optical coherence tomography Plaque characteristics in patients with ST-segment elevation myocardial infarction and early spontaneous reperfusion Feasibility study to improve deep learning in OCT diagnosis of rare retinal diseases with few-shot classification Functional characteristics of glaucoma related arcuate defects seen on OCT en face visualisation of the retinal nerve fibre layer