1. Articles from Miguel A. Materin

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    1. Microvascular Features of Treated Retinoblastoma Tumors in Children Assessed Using OCTA

      Microvascular Features of Treated Retinoblastoma Tumors in Children Assessed Using OCTA

      BACKGROUND AND OBJECTIVE: To describe the microvascular features of treated, clinically regressed, or reactivated retinoblastoma lesions using an investigational portable optical coherence tomography angiography (OCTA) system. PATIENTS AND METHODS: Single-center, prospective, cross-sectional, consecutive case-series of children with previously treated retinoblastoma who underwent portable OCTA of posterior retinoblastoma lesions. RESULTS: Eight tumors from seven eyes of five children with retinoblastoma were included. Tumors with types 1 (calcified remnant, n = 3), 2 (non-calcified remnant, n = 1), and 3 (both calcified and noncalcified remnants, n = 1) regression revealed persistent intrinsic superficial vasculature on OCTA (five of five lesions; 100%). Lesions with type 4 ...

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      Mentions: Duke University
    2. Hyperreflective Vitreous Opacities on Optical Coherence Tomography in a Patient With Bilateral Retinoblastoma

      Hyperreflective Vitreous Opacities on Optical Coherence Tomography in a Patient With Bilateral Retinoblastoma

      An investigational, portable spectral-domain optical coherence tomography (SD-OCT) unit revealed small hyperreflective opacities in both eyes of a patient with bilateral retinoblastoma. There was no evidence of vitreous seeding on ophthalmoscopy of either eye. Although the opacities may initially raise concern for potential vitreous seeding, this report suggests alternate potential etiologies for such opacities, which were also seen on imaging of a cohort of normal eyes in pediatric patients.

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    3. Vascular Findings In A Small Retinoblastoma Tumor Using OCT-A

      Vascular Findings In A Small Retinoblastoma Tumor Using OCT-A

      Retinoblastoma (RB) is the most common primary intraocular malignancy of children. 1 Improvements in screening tactics and treatment methods have dramatically increased both patient and globe survival. 1,2 Imaging modalities such as fluorescein angiography (FA) have demonstrated retinal vascular abnormalities in both large and small caliber retinal vessels in eyes with retinoblastoma, 1 and optical coherence tomography (OCT) can reveal or confirm otherwise subclinical lesions. 2 OCT angiography (OCT-A) is a non-invasive imaging modality allowing for in vivo visualization of retinal and choroidal vasculature.

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      Mentions: Duke University
    4. Optical Coherence Tomography Of Optic Disk Melanocytoma In 15 Cases.

      Optic disk melanocytoma showed a nodular configuration with sloping margins by optical coherence tomography. In all 15 cases, the tumor displayed a thin hyperreflective anterior surface and dense shadowing, giving the appearance of an optically empty mass.Page: 441DOI: 10.1097/IAE.0b013e31815e9853Authors: SHIELDS, CAROL L. MD; PEREZ, BENJAMIN MD; BENAVIDES, RAQUEL MD; MATERIN, MIGUEL A. MD; SHIELDS, JERRY A. MD
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    5. Early Macular Morphological Changes Following Plaque Radiotherapy For Uveal Melanoma.

      Optical coherence tomography (OCT) evidence of radiation-induced macular edema can be found as early as 4 months following plaque radiotherapy of uveal melanoma. OCT changes are apparent before clinical signs of classical radiation maculopathy and before substantial visual deterioration occurs. The development of macular edema is significantly associated with larger initial tumor size.Page: 263DOI: 10.1097/IAE.0b013e31814b1b75Authors: HORGAN, NOEL MD; SHIELDS, CAROL L. MD; MASHAYEKHI, ARMAN MD; TEIXEIRA, LUIZ F. MD; MATERIN, MIGUEL A. MD; SHIELDS, JERRY A. MD
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    6. Autofluorescence Of Orange Pigment Overlying Small Choroidal Melanoma.

      Orange pigment overlying small choroidal melanoma shows bright hyperautofluorescence, contrasting with isoautofluorescence of the underlying tumor.Page: 1107DOI: 10.1097/IAE.0b013e31814934efAuthors: SHIELDS, CAROL L. MD; BIANCIOTTO, CARLOS MD; PIRONDINI, CESARE MD; MATERIN, MIGUEL A. MD; HARMON, SARAH A. BS; SHIELDS, JERRY A. MD
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    1-7 of 7
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    1. (4 articles) Duke University
    2. (3 articles) Thomas Jefferson University
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    Imaging infant retinal vasculature with optical coherence tomography angiography Vascular Findings In A Small Retinoblastoma Tumor Using OCT-A Hyperreflective Vitreous Opacities on Optical Coherence Tomography in a Patient With Bilateral Retinoblastoma Microvascular Features of Treated Retinoblastoma Tumors in Children Assessed Using OCTA The Structural and Comparative Analysis of Intravitreal Dexamethasone Implant (Ozurdex) and Anti-VEGF Injection in Branched Retinal Vein Occlusion Patients by Optical Coherence Tomography Angiography Images Quantitation Vascular Responses to First-Generation Sirolimus-Eluting Stents and Bare-Metal Stents Beyond 10 Years Ocular Parameters Evaluation in Relation to the Refractive Error using Optical Coherence Topography Micro Optical Coherence Tomography for Coronary Imaging Macular Vessel Density in Diabetic Retinopathy Patients: How Can We Accurately Measure and What Can It Tell Us? Systems and methods for long working distance optical coherence tomography (OCT) Evaluation of the retinal nerve fiber layer with optic coherence tomography in patients with alcohol use disorder Predictive OCTA Biomarkers After Endoscopic Endonasal Pituitary Surgery