1. Articles from Shoji Kishi

    1-17 of 17
    1. Optical coherence tomography patterns and outcomes of contusion maculopathy caused by impact of sporting equipment

      Optical coherence tomography patterns and outcomes of contusion maculopathy caused by impact of sporting equipment

      Background To describe the patterns and outcomes of contusion maculopathy after ocular contusions resulting from accidental impact with sporting equipment. Methods We conducted a retrospective study of interventional case series. Patient Population: Twenty-one eyes of 21 patients who sustained blunt ocular trauma while playing a sport. Intervention/Observation Procedure(s): Surgery or observation by optical coherence tomography (OCT). Main Outcome Measure(s): The morphologic changes within the macula in the early stages after injury and changes in visual function in the early and recovery stages after injury. Results In the early stage, OCT visualized four injury patterns: type Ι, commotio retinae ...

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      Mentions: Gunma University
    2. Observation of neovascularization of the disc associated with proliferative diabetic retinopathy using OCT angiography

      Observation of neovascularization of the disc associated with proliferative diabetic retinopathy using OCT angiography

      Purpose To describe the relationship between the vitreous and the neovascularization of the disc (NVD) using swept source optical coherence tomography (SS-OCT) and OCT angiography (OCTA). Study design Retrospective. Methods We examined 17 eyes of 11 consecutive patients diagnosed as NVD associated with proliferative diabetic retinopathy (PDR). The location of the NVD feeder or collector vessels were examined by using RTVue XR Avanti. To determine the condition of the posterior vitreous detachment (PVD) and the proliferative tissue of the NVD, we performed 12 mm horizontal and vertical scans through the disc using SS-OCT. Results OCT images of all 17 cases ...

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    3. Impact of swept source optical coherence tomography on ophthalmology

      Impact of swept source optical coherence tomography on ophthalmology

      Swept source optical coherence tomography (SS-OCT) was introduced in clinical practice in 2012. Because of its deeper penetration and faster acquisition time, SS-OCT has the ability to visualize choroid, vitreous, and retinal structures behind dense preretinal hemorrhages. Swept source optical coherence tomography has positively influenced and hugely contributed to the research of the vitreous body. It is the first ophthalmic diagnostic technology to demonstrate the entire structure of the posterior precortical vitreous pocket (PPVP) in vivo . The roles of the PPVP in physiological posterior vitreous detachment and vitreoretinal interface disorders have now been elucidated. The presence of a connecting channel ...

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      Mentions: Gunma University
    4. En Face Imaging of Posterior Precortical Vitreous Pockets Using Swept-Source Optical Coherence Tomography

      En Face Imaging of Posterior Precortical Vitreous Pockets Using Swept-Source Optical Coherence Tomography

      PURPOSE. To obtain sequential flat (en face) images of posterior precortical vitreous pockets (PPVPs) using swept-source optical coherence tomography (SS-OCT). METHODS. We performed SS-OCT in the right eyes of 112 volunteers (mean age, 30.1 years; mean refraction, 2.5 diopters) while sitting using 12-mm horizontal, vertical scans of the 12- 3 9-mm plane 3 2.6-mm depth through the macula and optic disc. En face images of the posterior vitreous were obtained by En-View, a SS-OCT program. RESULTS. Swept-source OCT visualized the PPVPs and Cloquet’s canals in all subjects; the PPVPs appeared as boat-shaped lacunae in the horizontal ...

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      Mentions: Gunma University
    5. Posterior Vitreous Mobility Delineated by Tracking of Optical Coherence Tomography Images in Eyes with Idiopathic Macular Holes

      Posterior Vitreous Mobility Delineated by Tracking of Optical Coherence Tomography Images in Eyes with Idiopathic Macular Holes

      Purpose To demonstrate the posterior vitreous mobility following eye movements in patients forming macular holes, using an optical coherence tomography (OCT) eye tracking system. Design Prospective consecutive interventional case series. Methods Twenty four eyes of seventeen consecutive patients with idiopathic macular hole and the remaining fellow eyes were recruited. Following acquisition of baseline fundus scans, all patients were instructed to perform sets of standardized full excursion, vertical and horizontal eye movements. Immediately after each set of movements an OCT scan registered to the baseline fundus image was obtained using the eye tracking system. Three images were then overlaid using picture-editing ...

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    6. Posterior Precortical Vitreous Pockets and Connecting Channels in Children on Swept-Source Optical Coherence Tomography

      Posterior Precortical Vitreous Pockets and Connecting Channels in Children on Swept-Source Optical Coherence Tomography

      PURPOSE. To observe the posterior vitreous in children using swept-source optical coherence tomography (SS-OCT). METHODS. The normal right eyes of 73 children (ages, 3-11) years were studied using SS-OCT with 12-mm horizontal and vertical scans in the posterior fundus. RESULTS. Posterior precortical vitreous pockets (PPVPs), narrow liquefied spaces along the vitreoretinal interface in the macula (mean, 165.4±35.2 µm (depth) x 3,327±615.7 µm (width), were observed at age 3 in horizontal scans. The PPVPs enlarged to 382.9±51.8 x 4,486.5±342.3 from ages 4 to 6 (P<0.01) and ...

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      Mentions: Gunma University
    7. Vitreous Changes in High Myopia Observed by Swept-Source Optical Coherence Tomography

      Vitreous Changes in High Myopia Observed by Swept-Source Optical Coherence Tomography

      PURPOSE. To observe vitreous changes in high myopia using swept-source optical coherence tomography (SS-OCT). METHODS. We performed slit-lamp biomicroscopy and SS-OCT in the highly myopic right eyes of 151 patients (mean age, 52.7 years; mean refraction, -11.4 diopters [D]) and the right eyes with no myopia of 363 healthy control volunteers (mean age, 52.8 years; mean refraction, -1.4 D). To estimate the sizes of the posterior precortical vitreous pockets (PPVPs), we measured the height between the fovea and the anterior border of the PPVPs. RESULTS. Patients with partial posterior vitreous detachments (PVDs) around the macula and ...

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      Mentions: Gunma University
    8. Circle and Grid-wise Analyses of Peripapillary Nerve Fiber Layers by Spectral Domain Optical Coherence Tomography in Early Stage Glaucoma

      Circle and Grid-wise Analyses of Peripapillary Nerve Fiber Layers by Spectral Domain Optical Coherence Tomography in Early Stage Glaucoma

      PURPOSE. To study diagnostic performances of circle and grid-wise analyses of peripapillary retinal nerve fiber layer thickness (RNFLT) using spectral domain optical coherence tomography (SD-OCT) in early stage glaucoma. METHODS. Eighty-nine open-angle glaucoma (OAG) eyes (mean deviation, -2.5 ± 1.8 dB) and 89 age-matched normal eyes were studied. Peripapillary RNFLT was analyzed using SD-OCT raster scan in a 6.0 × 6.0 mm area. Averaged RNFLT was calculated over 0.1 × 0.1, 0.21 × 0.21, or 0.42 × 0.42 mm grids in the peripapillary area (grid method), or arcuate sector areas between 2.8 and 4 ...

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    9. Observation of Posterior Precortical Vitreous Pocket Using Swept Source Optical Coherence Tomography

      Observation of Posterior Precortical Vitreous Pocket Using Swept Source Optical Coherence Tomography

      Purpose: To observe posterior precortical vitreous pockets (PPVPs) using swept-source optical coherence tomography (SS-OCT). Methods: We performed SS-OCT in both eyes of 58 volunteers (36 men, 22 women) using 12-mm horizontal vertical scans through the macula and optic disc. To minimize age-related changes (liquefaction or posterior vitreous detachment), all subjects were a mean of 26.2 years (range, 22-40 years). The refractive errors ranged from -9.5 diopters (D) to +3.0 D. To estimate the PPVP size, we measured the height between the fovea and the anterior border of the PPVP and the maximal width in the 12-mm horizontal ...

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      Mentions: Gunma University
    10. Reproducibility of Thickness Measurements of Macular Inner Retinal Layers Using SD-OCT with or without Correction of Ocular Rotation

      Reproducibility of Thickness Measurements of Macular Inner Retinal Layers Using SD-OCT with or without Correction of Ocular Rotation

      Purpose. To evaluate the inter-visit reproducibility of spectral-domain optical coherence tomography (SD-OCT) measurement of the macular retinal nerve fiber layer thickness (mRNFLT), combined ganglion cell layer and inner plexiform layer (GCL+IPL) thickness, and ganglion cell complex (GCC) thicknesses (sum of mRNFLT and GCL+IPL thicknesses) compared with that of circumpapillary RNFLT (cpRNFLT) and the effect of ocular rotation on reproducibility. Methods. SD-OCT imaging was performed twice on different days in one eye of 58 normal subjects and 73 glaucoma patients. The reproducibility was evaluated for the entire 4.8 mm x 4.8 mm macular area and sub-areas (upper ...

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    11. Effects of Age, Sex, and Axial Length on the Three-Dimensional Profile of Normal Macular Layer Structures

      Effects of Age, Sex, and Axial Length on the Three-Dimensional Profile of Normal Macular Layer Structures
      Purpose. To identify sex-related differences and age-related changes in individual retinal layer thicknesses in a population of healthy eyes across the lifespan, using spectral domain optical coherence tomography (SD-OCT). Methods. In seven institutes in Japan, mean thicknesses of the retinal nerve fiber layer (RNFL), ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer (INL), outer plexiform layer (OPL), outer nuclear layer (ONL), photoreceptor inner segment (IS), and photoreceptor outer segment (OS) were measured using SD-OCT with a new automated segmentation protocol in 256 healthy subjects. Results. Interoperator coefficients of variability for measurements of each layer ranged from 0 ...
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    12. Improved Visualization of Henle Fiber Layer By Changing the Measurement Beam Angle on Optical Coherence Tomography

      Improved Visualization of Henle Fiber Layer By Changing the Measurement Beam Angle on Optical Coherence Tomography
      Purpose: The outer plexiform layer (OPL) includes the photoreceptor synapse layer and Henle fiber layer (HFL) in the macular area. We attempted to improve optical coherence tomography imaging of the HFL by changing the angle of the measurement beam. Methods: Thirteen normal eyes underwent spectral domain optical coherence tomography. To focus the angle of the measurement beam perpendicular to the obliquely oriented HFL, the beam in the optical coherence tomography system was aimed at the periphery of the pupil. Results: The cross-sectional image of the macular area was inclined right or left if the beam entered from the periphery of ...
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    13. Peripapillary Retinal Nerve Fiber Layer Thickness Determined by Spectral-Domain Optical Coherence Tomography in Ophthalmologically Normal Eyes

      Peripapillary Retinal Nerve Fiber Layer Thickness Determined by Spectral-Domain Optical Coherence Tomography in Ophthalmologically Normal Eyes
      Objectives  To evaluate the peripapillary distribution of retinal nerve fiber layer thickness (RNFLT) in normal eyes using spectral-domain optical coherence tomography and to study potentially related factors. Methods  In 7 institutes in Japan, RNFLT in 7 concentric peripapillary circles with diameters ranging from 2.2 to 4.0 mm were measured using spectral-domain optical coherence tomography in 251 ophthalmologically normal subjects. Multiple regression analysis for the association of RNFLT with sex, age, axial length, and disc area was performed. Results  Retinal nerve fiber layer thickness decreased linearly from 125 to 89 µm as the measurement diameter increased (P < .001, mixed linear model). Retinal nerve fiber layer thickness correlated with age in all diameters (partial correlation coefficient [PCC] = –0.40 to –0.32; P < .001) and negatively correlated with disc area in the 2 innermost circles but positively correlated in the 3 outermost circles (PCC = –0.30 to –0.22 and 0.17 to 0.20; P ≤ .005). Sex and axial length did not correlate with RNFLT (P > .08). The ...
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    14. Three-dimensional Profile of Macular Retinal Thickness in Normal Japanese Eyes

      Purpose: To demonstrate the 3-dimensional macular thickness distribution in normal subjects by spectral domain optical coherence tomography (SD-OCT) and evaluate its association with sex, age, and axial length. Methods: Mean regional retinal thickness measurements on the Early Treatment Diabetic Retinopathy Study (ETDRS) layout were obtained by 3-dimensional raster scanning (6 X 6 mm) using SD-OCT in 248 normal eyes of 248 Japanese subjects. Results: Mean foveal thickness was 222 ± 19 µm; it was significantly greater in men (226 ± 19 µm) than in women (218 ± 18 µm; P = 0.002) and did not correlate with age in either sex. Mean sectorial ...
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    15. Restored Photoreceptor Outer Segment Damage in Multiple Evanescent White Dot Syndrome

      Purpose: To report retinal tomography and function in the course of multiple evanescent white dot syndrome (MEWDS). Design: Prospective case series.Participants: Seven patients with unilateral MEWDS. Methods: We performed optical coherence tomography (OCT), multifocal electroretinography (mfERG), full-field electroretinography (ffERG), fluorescein and indocyanine green angiography, and visual field examinations in 7 patients with active to resolved MEWDS. Main Outcome Measures: OCT imaging of the posterior fundus with a 6×6-mm square, best-corrected visual acuity (BCVA), fundus characteristics, visual field measurements, mfERG, and ffERG responses.Results: All patients reported unilateral blurred vision and spotty visual field defects. The fundi had yellow ...
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      Mentions: Gunma University
    16. Outer Nuclear Layer Thickness at the Fovea Determines Visual Outcomes in Resolved Central Serous Chorioretinopathy

      Purpose: To determine a correlation between foveal morphologic changes and visual outcomes in patients with resolved central serous chorioretinopathy (CSC).Design: Observational case series.Methods: We measured the outer nuclear layer (ONL) thickness at the central fovea and evaluated the integrity of the photoreceptor inner and outer segment junction (IS/OS) using spectral-domain optical coherence tomography in 67 eyes (65 patients) with resolved CSC. The patients were divided into 2 groups: group A included 24 eyes (23 patients) with best-corrected visual acuity (BCVA) of less than 1.0, and group B included 43 eyes (42 patients) with BCVA of 1 ...
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    17. Foveal Thickness Can Predict Visual Outcome in Patients with Persistent Central Serous Chorioretinopathy

      Aims: To evaluate relationships between visual prognosis and foveal thickness measured by optical coherence tomography in patients with unilateral persistent central serous chorioretinopathy. Methods: Fifteen eyes of fifteen patients with symptoms for more than 6 months were evaluated on visual acuity and foveal thickness before and after foveal reattachment. Results: Mean age was 49.7 years (range 34-69), symptoms prolonged for 21.8 months (7-36), logarithm of the minimum angle of resolution (LogMAR) was 0.27 (decimal visual acuity 0.53). After foveal reattachment, LogMAR was 0.16 (0.69). Final foveal thickness (mean 109 µm) was thinner than that ...
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      Mentions: Gunma University
    1-17 of 17
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    Peripapillary Retinal Nerve Fiber Layer Thickness Determined by Spectral-Domain Optical Coherence Tomography in Ophthalmologically Normal Eyes Improved Visualization of Henle Fiber Layer By Changing the Measurement Beam Angle on Optical Coherence Tomography Effects of Age, Sex, and Axial Length on the Three-Dimensional Profile of Normal Macular Layer Structures Reproducibility of Thickness Measurements of Macular Inner Retinal Layers Using SD-OCT with or without Correction of Ocular Rotation Observation of Posterior Precortical Vitreous Pocket Using Swept Source Optical Coherence Tomography En Face Imaging of Posterior Precortical Vitreous Pockets Using Swept-Source Optical Coherence Tomography Correlation between optical coherence tomography, multifocal electroretinogram findings and visual acuity in diabetic macular edema Ciliary body length revisited by anterior segment optical coherence tomography: implications for safe access to the pars plana for intravitreal injections Evaluation of retinal vascular structure after epiretinal membrane surgery by optical coherence tomography angiography Bivalirudin vs. Heparin on Radial Artery Thrombosis during Transradial Coronary Intervention: An Optical Coherence Tomography Study Superficial Calcification With Rotund Shape Is Associated With Carotid Plaque Rupture: An Optical Coherence Tomography Study Longitudinal retinal layer changes in preclinical Alzheimer’s disease