1. Articles from Sanjiv S. Gambhir

    1-2 of 2
    1. Optical coherence contrast imaging using gold nanorods in living mice eyes

      Optical coherence contrast imaging using gold nanorods in living mice eyes

      Background Optical Coherence Tomography (OCT) is a powerful imaging modality to visualize tissue structures, with axial image pixel resolution as high as 1.6 um in tissue. However, OCT is intrinsically limited to providing structural information as the OCT contrast is produced by optically scattering tissues. Methods Here we demonstrate gold nanorods (GNRs) injected into the anterior chamber (AC) and cornea of mice eyes can create a significant OCT signal and hence can be used as a contrast agent for in vivo OCT imaging. Results We show that a low dose of 30 nM of GNRs (13 nm in diameter ...

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    2. Early Diagnosis of Ovarian Carcinoma: Is a Solution in Sight?

      Early Diagnosis of Ovarian Carcinoma: Is a Solution in Sight?
      Ovarian cancer is the most lethal of the gynecologic malignancies. Because ovarian cancer symptoms are subtle and nonspecific, the diagnosis is often delayed until the disease is well advanced. Overall 5-year survival is a rather dismal 50% but can be improved to greater than 90% if the disease is confined to the ovary at the time of diagnosis (generally in fewer than 25% of patients). Effective screening tools are currently not available. Owing to the rather low incidence of the disease in the general population, potential screening tests must provide very high specificity to avoid unnecessary interventions in false-positive cases ...
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    1-2 of 2
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  2. Topics in the News

    1. (2 articles) Stanford University
    2. (1 articles) National Institutes of Health
    3. (1 articles) University of Miami
    4. (1 articles) Marco B. Ruggeri
    5. (1 articles) Adam de la Zerda
    6. (1 articles) Carl Zeiss Meditec
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    Early Diagnosis of Ovarian Carcinoma: Is a Solution in Sight? Optical coherence contrast imaging using gold nanorods in living mice eyes Non Exudative AMD Imaged With SS-OCT- Extension High space-bandwidth in quantitative phase imaging using partially spatially coherent optical coherence microscopy and deep neural network Optical coherence tomography assessment of macrophages accumulation in non-ST-segment elevation acute coronary syndromes Early disability in ambulatory patients with multiple sclerosis: optical coherence tomography versus visual evoked potentials, a comparative study Dueling Deep Q-Network for Unsupervised Inter-frame Eye Movement Correction in Optical Coherence Tomography Volumes Atlas of Optical Coherence Tomography for Glaucoma (Textbook) In-vivo analysis of iron-gold composite nanoparticles as potential exogenous contrast agents for Magnetomotive Optical Coherence Tomography (MMOCT) Automatic Classification of Volumetric Optical Coherence Tomography Images via Recurrent Neural Network Noise-Powered Disentangled Representation for Unsupervised Speckle Reduction of Optical Coherence Tomography Images Circadian variations in pathogenesis of ST-segment elevation myocardial infarction: an optical coherence tomography study